Monitoring blood glucose in pregnant women receiving betamethasone for fetal lung development

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the changes in maternal blood glucose levels in non-diabetic pregnant women receiving betamethasone for fetal lung maturation during threatened preterm birth. Participants will be monitored using continuous glucose monitoring (CGM) to assess glycemic responses over a period of six days. Blood samples will also be collected to measure various metabolic markers, providing a comprehensive understanding of how betamethasone affects glucose homeostasis in this population. The study seeks to fill the knowledge gap regarding the effects of corticosteroids on non-diabetic pregnant women, which has been less explored compared to diabetic counterparts.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Pregnant in gestational week 24+0 - 34+0 admitted with symptoms of threatened preterm birth:

  * Premature contractions and shortening of the cervix, or
  * Preterm premature rupture of membranes.
* Treatment with betamethasone for fetal lung maturation is planned, or started (maximum 4 hours before inclusion)
* Age over 18 years
* Read and understand Danish

Exclusion Criteria:

* Multiple pregnancy
* Diabetes
* Pre-existing maternal use of medications that affect glucose metabolism

Where it's running

• Aarhus University Hospital
  Aarhus, Central Region Denmark, Denmark Recruiting

Study contacts

• Study coordinator: Victoria Bøttker
• Email: victoria.boettker@gmail.com
• Phone: +45 21253835

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.