Condition

PCOS clinical trials and research

• 14Clinical trials
• 11NIH research projects
• 1New in 30 days
• 6Countries

Newest PCOS clinical trials

All recruiting trials (14)

• PMOS and Sleep Apnea: A Pilot Look at Mitochondrial Function

  In women with PMOS, this pilot study tests whether sleep apnea treatment with CPAP improves mitochondrial function in leg muscle tissue.

  Recruiting University of Chicago · Chicago, Illinois · NCT07871149

• PCOS and Brain Health

  This study tests how PCOS may affect brain blood flow, brain structure, and thinking skills in reproductive-age people with and without PCOS.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07727512

• Adding cabergoline to letrozole for ovulation in PCOS

  This study will see if adding cabergoline to letrozole helps women with PCOS ovulate more often.

  Recruiting Bangladesh Medical University · Dhaka, Shahbag · NCT07255911

• Investigating cardiovascular markers in women with PCOS during glucose testing

  This study is testing how glucose testing affects heart health markers in women with PCOS and whether different treatments can improve those markers over six months.

  Recruiting Attikon Hospital · Chaïdári · NCT06889454

• PIMS versus PGT-A for embryo selection in women with PCOS

  This test will see if selecting embryos with Pre-implantation Methylation Screening (PIMS) instead of PGT-A plus standard morphology leads to higher cumulative live birth rates and lower early pregnancy loss for women with PCOS undergoing IVF/ICSI.

  Recruiting First Affiliated Hospital, Sun Yat-Sen University · Zhongshan, Guangdong · NCT06887881

• Comparing adipokine levels in women with and without PCOS

  This study is trying to see how levels of certain fat-related proteins differ in women with polycystic ovary syndrome (PCOS), both with and without insulin resistance, compared to women without PCOS.

  Recruiting Jagiellonian University · Krakow · NCT06793072

• Using liraglutide to improve fertility in obese women with PCOS

  This study is testing if giving liraglutide, along with metformin, can help obese women with PCOS improve their chances of having a baby through IVF by losing weight and getting healthier.

  Recruiting Phase 4 Peking University Third Hospital · Beijing, Beijing Municipality and 2 other locations · NCT06742710

• In vitro maturation of human eggs for fertility treatment

  This study is testing a new way to help women with fertility issues by maturing their eggs in the lab with fewer hormones to see if it makes treatment easier and safer.

  Recruiting Colorado Center for Reproductive Medicine · Lone Tree, Colorado · NCT06633120

• Fish oil plus metformin for heart health in women with PCOS

  This trial will test whether taking dietary fish oil with metformin improves heart-related measures, blood fats, and insulin–glucose control in overweight women with PCOS, including some with type 2 diabetes.

  Recruiting at 3 sites Phase 1 University of Alberta · Edmonton, Alberta and 2 other locations · NCT06424860

• Using ketone supplements to improve heart health in women with PCOS

  This study tests if taking ketone supplements can help improve heart health in women aged 18 to 40 who have polycystic ovary syndrome (PCOS).

  Recruiting McGill University · Montreal, Quebec · NCT06155708

• Using stem cells from umbilical cords to treat Polycystic Ovary Syndrome

  This study is testing whether stem cells from umbilical cords can help women with Polycystic Ovary Syndrome feel better and improve their symptoms.

  Recruiting at 2 sites Phase 1 The Foundation for Orthopaedics and Regenerative Medicine · Naples, Florida and 1 other locations · NCT06143527

• Investigating how androgens affect liver health in young women

  This study is trying to see how hormones called androgens affect liver health in young women, especially those with polycystic ovary syndrome, by comparing liver disease progression between women with and without this condition.

  Recruiting University of California, San Francisco · San Francisco, California and 1 other locations · NCT06124261

• Bicalutamide treatment for young women with liver disease and PCOS

  This study is testing if a medication called bicalutamide can help young women with liver disease and PCOS feel better and improve their liver health.

  Recruiting Phase 1 University of California, San Francisco · San Francisco, California · NCT05979389

• Study on the health effects of children born to mothers with PCOS

  This study looks at how being born to mothers with Polycystic Ovary Syndrome (PCOS) affects children's health both now and in the future.

  Recruiting Guangzhou Women and Children's Medical Center · Guangzhou, Guangdong · NCT03742011

NIH-funded research (11)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Genetically Validated PCOS Subtypes for Better Diagnosis and Risk Stratification

  Aimed at women with polycystic ovary syndrome (PCOS), this project uses genetic data and patient characteristics to define distinct PCOS subtypes and improve how we diagnose and estimate risk.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11623556

• Understanding how PCOS develops during adolescence

  This grant looks at how polycystic ovary syndrome begins in teenagers and what early signs help doctors diagnose it accurately.

  NIH research Cornell University · Ithaca, United States · NIH-11378637

• Genetically guided PCOS subtypes to improve diagnosis and risk stratification

  Aims to use genetic patterns to identify PCOS subtypes so doctors can diagnose it more precisely and tailor risk predictions for each patient.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11298558

• Using inositol to improve reproductive and metabolic health in women with PCOS

  This study is looking at how taking inositol might help women with polycystic ovary syndrome (PCOS) by checking its effects on hormone levels and overall health over three months.

  NIH research Pennsylvania State Univ Hershey Med Ctr · Hershey, United States · NIH-11167238

• Understanding how dopamine affects reproductive hormone release in women with PCOS

  This study is looking at how certain brain cells that control hormone release can help women with reproductive issues like PCOS and hypothalamic amenorrhea, and it’s testing if a compound that affects these cells can help balance hormone levels.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11160997

• Investigating how genetic variations in gonadotropin pathways affect PCOS

  This study is looking at how our genes might play a role in Polycystic Ovary Syndrome (PCOS) to help find better treatments for women dealing with this condition.

  NIH research Northwestern University at Chicago · Chicago, United States · NIH-11069504

• Examining how physical activity affects the risk of PCOS in young girls

  This study is looking at how physical activity can help girls aged 8 to 10 who are at risk for Polycystic Ovary Syndrome (PCOS) by tracking their insulin and hormone levels while they try out a special exercise program to see if it can improve their health.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-10988317

• Understanding how PCOS affects adolescents in the U.S.

  This study is looking at how Polycystic Ovary Syndrome (PCOS) affects young people aged 12 to 20 in the U.S., focusing on their symptoms and related health issues, to find better treatment options just for them.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-10854803

• Understanding the genetic differences in PCOS among diverse populations

  This study is looking at the genes that might play a role in polycystic ovary syndrome (PCOS) to help understand the different types of PCOS women can have, which could lead to better diagnoses and personalized treatments just for them.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-10838466

• Investigating variations in the AMH signaling pathway related to PCOS

  This study is looking at how certain genes related to a hormone called anti-Müllerian hormone might affect women with Polycystic Ovary Syndrome (PCOS), with the goal of helping to improve understanding and treatment of this condition.

  NIH research Northwestern University at Chicago · Chicago, United States · NIH-10818355

• Using inositol to improve reproductive and metabolic health in women with PCOS

  This study is looking at how taking inositol might help women with Polycystic Ovary Syndrome (PCOS) by checking if it can improve hormone levels and insulin response over three months.

  NIH research Pennsylvania State Univ Hershey Med Ctr · Hershey, United States · NIH-10475570

Related topics

Quick answers

How many PCOS clinical trials are recruiting right now?

14, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (6 trials), China (3 trials), Greece (2 trials), Canada (2 trials), Poland (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 3, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →