Using inositol to improve reproductive and metabolic health in women with PCOS
Inositol Supplementation to Treat Reproductive and Metabolic Dysfunction in Polycystic Ovary Syndrome: A Double Blind RCT (INSUPP-PCOS)
This study is looking at how taking inositol might help women with polycystic ovary syndrome (PCOS) by checking its effects on hormone levels and overall health over three months.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State Univ Hershey Med Ctr NIH-funded |
| Lab location | 1 site (Hershey, United States) |
| Project ID | NIH-11167238 on NIH RePORTER |
What this research studies
This research investigates the effects of inositol supplementation on women diagnosed with polycystic ovary syndrome (PCOS), a condition that can cause reproductive and metabolic issues. The study involves a double-blind, randomized clinical trial where participants will receive either inositol or a placebo over a three-month period. The goal is to assess how different doses of inositol can impact hormone levels and metabolic health in women with PCOS. Participants will be monitored for changes in serum testosterone levels and other health markers.
Who could benefit from this research
Good fit: Ideal candidates for this research are women diagnosed with polycystic ovary syndrome who are experiencing reproductive and metabolic dysfunction.
Not a fit: Patients who do not have polycystic ovary syndrome or those who are not experiencing reproductive or metabolic issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new dietary supplement option for women with PCOS to help manage their symptoms and improve their reproductive and metabolic health.
How similar studies have performed: Previous research has shown promising results with inositol supplementation in managing symptoms of PCOS, making this study a continuation of exploring its efficacy.
Where this research is happening
Hershey, United States
- Pennsylvania State Univ Hershey Med Ctr — Hershey, United States (Active)
Researchers
- Principal investigator: Legro, Richard S. — Pennsylvania State Univ Hershey Med Ctr
- Study coordinator: Legro, Richard S.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.