Comparing adipokine levels in women with and without PCOS
Official title: Assessment of Adipokine Concentrations and Their Association With the Metabolic Profile of Women With PCOS
Run by Jagiellonian University · NCT06793072 · Data updated 2026-11-12
This study is trying to see how levels of certain fat-related proteins differ in women with polycystic ovary syndrome (PCOS), both with and without insulin resistance, compared to women without PCOS.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 45 Years |
| Sex | Women only |
| Enrollment | 300 (estimated) |
| Sponsor | Jagiellonian University Academic / other |
| Locations | 1 site (Krakow) |
| Status | Recruiting |
| Started | January 20, 2025 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | March 18, 2026 |
| Trial ID | NCT06793072 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are women aged 18-45 who have been diagnosed with polycystic ovary syndrome or are healthy controls without PCOS.
✕Probably not a fit
Patients who have had at least one ovary removed, or those with treated diabetes, metabolic diseases, autoimmune diseases, or autoinflammatory diseases may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to measure and compare the concentrations of adipokines, specifically leptin, resistin, and omentin-1, in three groups of women: those with polycystic ovary syndrome (PCOS) without insulin resistance, those with PCOS with insulin resistance, and women without PCOS. The study seeks to elucidate the role of these adipokines in the etiology of PCOS and their association with insulin resistance, which is linked to various health complications. Blood samples will be analyzed using immunoenzymatic methods (ELISA) and a biochemical analyzer to determine the concentrations of the selected adipokines.
Why it matters
Potential benefit: If successful, this study could lead to better understanding and identification of biomarkers for insulin resistance in women with PCOS, potentially improving management and treatment strategies.
How similar studies have gone: While the role of adipokines in PCOS has been explored, this study's specific focus on comparing these markers across different PCOS phenotypes is a novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18-45 Exclusion Criteria: * previous removal of at least one ovary * treated diabetes of any type * diagnosed and treated metabolic diseases * diagnosed and treated autoimmune diseases * diagnosed and treated autoinflammatory diseases(Edited)Restore original
Where it's running
-
Jagiellonian Univeristy
Krakow, Poland Recruiting
Study contacts
- Study coordinator: Iwona Gawron, Ph.D., M.D.
- Email: iwona.gawron@uj.edu.pl
- Phone: +48 124248570
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.