Study on the health effects of children born to mothers with PCOS
Health of Offspring Born to Mothers With Polycystic Ovary Syndrome in Guangzhou Cohort Study
This study looks at how being born to mothers with Polycystic Ovary Syndrome (PCOS) affects children's health both now and in the future.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2000 (estimated) |
| Ages | N/A to 18 Years |
| Sex | All |
| Sponsor | Guangzhou Women and Children's Medical Center Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT03742011 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the short- and long-term health effects on offspring born to mothers diagnosed with Polycystic Ovary Syndrome (PCOS) in Guangzhou, China. It collects data on maternal PCOS subtypes, nursing practices, diet, education, and health outcomes of the children as they grow. Biological samples, including blood and tissue, are also gathered to analyze the impact of prenatal exposure to hyperandrogenism and its potential link to glucolipid metabolism disorders in the offspring.
Who should consider this trial
Good fit: Ideal candidates for this study are offspring born to women diagnosed with PCOS who are permanent residents or families intending to remain in Guangzhou for at least three years.
Not a fit: Patients who do not have a mother diagnosed with PCOS may not receive any benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into the health risks faced by children born to mothers with PCOS, potentially leading to better management and preventive strategies.
How similar studies have performed: While studies on PCOS and its effects on offspring are ongoing, this specific cohort approach focusing on the long-term health outcomes in a Chinese population is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Offspring born to women diagnosed with PCOS * Offspring born to women with \<20 weeks of gestation, intended to eventually deliver in Guangzhou Women and Children's Medical Center * Permanent residents or families intended to remain in Guangzhou for ≥3 years Exclusion Criteria: * None
Where this trial is running
Guangzhou, Guangdong
- Guangzhou Women and Children's Medical Center, China — Guangzhou, Guangdong, China (Recruiting)
Study contacts
- Principal investigator: Xiu Qiu, PhD — Guangzhou Women and Children's Medical Center, China
- Study coordinator: Xiu Qiu, PhD
- Email: qxiu0161@163.com
- Phone: 0086 20 38367160
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.