Clinical trial Recruiting at 1 site Observational Ages Any age to 18

Study on the health effects of children born to mothers with PCOS

Official title: Health of Offspring Born to Mothers With Polycystic Ovary Syndrome in Guangzhou Cohort Study

Run by Guangzhou Women and Children's Medical Center · NCT03742011 · Data updated 2026-11-12

This study looks at how being born to mothers with Polycystic Ovary Syndrome (PCOS) affects children's health both now and in the future.

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Quick facts

Study typeObservational
AgesAny age to 18 Years
SexAll
Enrollment2000 (estimated)
SponsorGuangzhou Women and Children's Medical Center
Academic / other
Locations1 site (Guangzhou, Guangdong)
StatusRecruiting
StartedFebruary 1, 2012
Main results expectedDecember 31, 2025
Study endsDecember 31, 2038
Registry record updatedFebruary 26, 2024
Trial IDNCT03742011 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are offspring born to women diagnosed with PCOS who are permanent residents or families intending to remain in Guangzhou for at least three years.

Probably not a fit

Patients who do not have a mother diagnosed with PCOS may not receive any benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the short- and long-term health effects on offspring born to mothers diagnosed with Polycystic Ovary Syndrome (PCOS) in Guangzhou, China. It collects data on maternal PCOS subtypes, nursing practices, diet, education, and health outcomes of the children as they grow. Biological samples, including blood and tissue, are also gathered to analyze the impact of prenatal exposure to hyperandrogenism and its potential link to glucolipid metabolism disorders in the offspring.

Why it matters

Potential benefit: If successful, this study could provide insights into the health risks faced by children born to mothers with PCOS, potentially leading to better management and preventive strategies.

How similar studies have gone: While studies on PCOS and its effects on offspring are ongoing, this specific cohort approach focusing on the long-term health outcomes in a Chinese population is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Offspring born to women diagnosed with PCOS
* Offspring born to women with \<20 weeks of gestation, intended to eventually deliver in Guangzhou Women and Children's Medical Center
* Permanent residents or families intended to remain in Guangzhou for ≥3 years

Exclusion Criteria:

* None

Where it's running

  • Guangzhou Women and Children's Medical Center, China
    Guangzhou, Guangdong, China
    Recruiting

Study contacts

  • Principal investigator: Xiu Qiu, PhD — Guangzhou Women and Children's Medical Center, China
  • Study coordinator: Xiu Qiu, PhD
  • Email: qxiu0161@163.com
  • Phone: 0086 20 38367160

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.