Using stem cells from umbilical cords to treat Polycystic Ovary Syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial investigates the safety and efficacy of intravenous delivery of cultured allogeneic adult umbilical cord derived mesenchymal stem cells for treating Polycystic Ovary Syndrome (PCOS). The study is based on previous findings that suggest stem cell treatment may resolve PCOS symptoms. Participants will receive approximately 2 million stem cells per kg of body weight, and their hormone levels and ultrasound results will be monitored at 3, 6, and 12 months post-treatment. The goal is to determine if this innovative approach can effectively reduce or eliminate the condition.

Why it matters

Who can join: the full rules

Inclusion Criteria:

• Ultrasound documented poly cystic ovary syndrome

Exclusion Criteria:

* Active infection
* Active cancer
* Chronic multisystem organ failure
* Pregnancy
* Clinically significant abnormalities on pre-treatment laboratory evaluation
* Medical condition that would (based on the opinion of the investigator) compromise patient's safety
* Continued drug abuse
* Previous organ transplant
* Hypersensitivity to sulfur
* Inability to supply proper informed consent

Where it's running

• Prodromos Stem Cell Institute
  Naples, Florida, United States Recruiting
• Prodromos Stem Cell Institute
  Athens, Greece Recruiting

Study contacts

• Study coordinator: Chadwick Prodromos, MD
• Email: care@thepsci.com
• Phone: 847-699-6810

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Using LC-MS/MS to profile androgens for PCOS diagnosis

  This study tests whether LC-MS/MS measurement of androgen profiles can help diagnose PCOS in women compared with healthy controls.

  Recruiting Women's Hospital School Of Medicine Zhejiang University · Hangzhou, Zhejiang · NCT07916909

• Brown adipose tissue responses in PCOS with infrared thermography and inositol

  This study tests whether brown fat activity, measured by infrared skin temperature and UCP-1 levels, differs among women with PCOS (normal weight or overweight/obese) and healthy controls, and whether 12 weeks of inositol changes those responses in overweight/obese PCOS participants.

  Recruiting at 2 sites Istanbul Health and Technology University · Istanbul and 1 other locations · NCT07896642

• PMOS and Sleep Apnea: A Pilot Look at Mitochondrial Function

  In women with PMOS, this pilot study tests whether sleep apnea treatment with CPAP improves mitochondrial function in leg muscle tissue.

  Recruiting University of Chicago · Chicago, Illinois · NCT07871149

• Precision acupuncture and lifestyle for PCOS

  This trial tests whether a precision acupuncture approach combined with a personalized lifestyle plan helps improve insulin resistance in people with PCOS compared with conventional acupuncture and standard lifestyle changes.

  Recruiting Peking University Third Hospital · Beijing, Beijing Municipality and 1 other locations · NCT07809503

• Orlistat for metabolic and hormonal features in women with PCOS

  This trial tests whether adding orlistat to lifestyle advice helps improve metabolic and hormonal aspects in women with PCOS compared to lifestyle advice alone.

  Recruiting Khyber Medical University Peshawar · Abbottābād, Khyber Pakhtunkhwa · NCT07747909

• PCOS and Brain Health

  This study tests how PCOS may affect brain blood flow, brain structure, and thinking skills in reproductive-age people with and without PCOS.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07727512

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.