Using inositol to improve reproductive and metabolic health in women with PCOS
Inositol Supplementation to Treat Reproductive and Metabolic Dysfunction in Polycystic Ovary Syndrome: A Double Blind RCT (INSUPP-PCOS)
This study is looking at how taking inositol might help women with Polycystic Ovary Syndrome (PCOS) by checking if it can improve hormone levels and insulin response over three months.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State Univ Hershey Med Ctr NIH-funded |
| Lab location | 1 site (Hershey, United States) |
| Project ID | NIH-10475570 on NIH RePORTER |
What this research studies
This research investigates the effects of inositol supplementation on women with Polycystic Ovary Syndrome (PCOS), a condition that causes reproductive and metabolic issues. The study will involve a double-blind, randomized controlled trial where participants will receive different doses of inositol or a placebo over three months. The primary goal is to assess changes in hormone levels and metabolic markers, such as insulin and glucose response. By restoring hormonal balance and improving insulin signaling, the research aims to provide insights into effective treatments for PCOS.
Who could benefit from this research
Good fit: Ideal candidates for this research are women diagnosed with Polycystic Ovary Syndrome who experience symptoms related to reproductive and metabolic dysfunction.
Not a fit: Patients who do not have Polycystic Ovary Syndrome or those with other underlying health conditions unrelated to PCOS may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved reproductive and metabolic health for women suffering from PCOS.
How similar studies have performed: Previous research has shown promising results with inositol supplementation in improving symptoms of PCOS, suggesting that this approach may be effective.
Where this research is happening
Hershey, United States
- Pennsylvania State Univ Hershey Med Ctr — Hershey, United States (Active)
Researchers
- Principal investigator: Legro, Richard S. — Pennsylvania State Univ Hershey Med Ctr
- Study coordinator: Legro, Richard S.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.