Using ketone supplements to improve heart health in women with PCOS

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of exogenous ketone monoester supplementation on cardiovascular health in females diagnosed with polycystic ovary syndrome (PCOS). PCOS is a common condition that can lead to serious cardiovascular issues due to insulin resistance and elevated blood pressure. The trial aims to determine whether ketone supplementation can improve markers of cardiovascular health in this population. Participants will be females aged 18 to 40 with a confirmed diagnosis of PCOS, and they will receive either ketone supplements or water as a control.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All female participants will report female sex assigned at birth
* All participants will be aged 18 to 40
* PCOS diagnosis

Exclusion Criteria:

* Current smokers or a prolonged history of smoking
* Presence or history of overt cardiometabolic disease (e.g., stage 2 hypertension, diabetes, heart disease), neurologic disease, or endocrinopathy (with the exception of PCOS)
* Current pregnancy or currently breastfeeding
* Current use of medications which may affect our outcomes of interest (e.g., anti-hypertensives, anti-androgens, metformin)

Where it's running

• Cardiovascular Health and Autonomic Research Laboratory
  Montreal, Quebec, Canada Recruiting

Study contacts

• Principal investigator: Charlotte Usselman, Ph.D — McGill University
• Study coordinator: Charlotte Usselman, Ph.D
• Email: charlotte.usselman@mcgill.ca
• Phone: 5143962140

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.