Understanding how PCOS affects adolescents in the U.S.
Official title: The presentation and medical course of PCOS in adolescents across the United States
Funded at University of Colorado Denver · NIH-10854803 · Data updated 2026-11-12
This study is looking at how Polycystic Ovary Syndrome (PCOS) affects young people aged 12 to 20 in the U.S., focusing on their symptoms and related health issues, to find better treatment options just for them.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | June 5, 2023 |
| Project end | May 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $174,334 |
| NIH project number | 5R21HD109488-02 |
| Project ID | NIH-10854803 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adolescents aged 12 to 20 who have been diagnosed with PCOS or exhibit symptoms of the condition.
✕Less likely to help
Patients outside the adolescent age range or those without a diagnosis of PCOS may not benefit from this research.
What this research studies
This research investigates the presentation and medical course of Polycystic Ovary Syndrome (PCOS) in adolescents aged 12 to 20 across the United States. It aims to explore the various symptoms and co-morbidities associated with PCOS, such as obesity, diabetes, and mental health disorders. By analyzing the differences in how PCOS manifests in young individuals compared to adults, the study seeks to identify effective treatment options tailored for this age group. The research will involve collecting data from participants to better understand the condition's impact on their health and well-being.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and management plans for adolescents with PCOS.
How similar studies have gone: While there have been small studies on PCOS in adults, this research focuses specifically on adolescents, making it a novel approach.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Cree, Melanie G — University of Colorado Denver
- Study coordinator: Cree, Melanie G
Related research
Other NIH-funded projects on the same topics.
-
Genetically Validated PCOS Subtypes for Better Diagnosis and Risk Stratification
Aimed at women with polycystic ovary syndrome (PCOS), this project uses genetic data and patient characteristics to define distinct PCOS subtypes and improve how we diagnose and estimate risk.
-
Understanding how PCOS develops during adolescence
This grant looks at how polycystic ovary syndrome begins in teenagers and what early signs help doctors diagnose it accurately.
-
Genetically guided PCOS subtypes to improve diagnosis and risk stratification
Aims to use genetic patterns to identify PCOS subtypes so doctors can diagnose it more precisely and tailor risk predictions for each patient.
-
Using inositol to improve reproductive and metabolic health in women with PCOS
This study is looking at how taking inositol might help women with polycystic ovary syndrome (PCOS) by checking its effects on hormone levels and overall health over three months.
-
Understanding how dopamine affects reproductive hormone release in women with PCOS
This study is looking at how certain brain cells that control hormone release can help women with reproductive issues like PCOS and hypothalamic amenorrhea, and it’s testing if a compound that affects these cells can help balance hormone levels.
-
Investigating how genetic variations in gonadotropin pathways affect PCOS
This study is looking at how our genes might play a role in Polycystic Ovary Syndrome (PCOS) to help find better treatments for women dealing with this condition.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.