Understanding how PCOS develops during adolescence
Official title: Emergence of polycystic ovary syndrome (PCOS) during adolescence
Funded at Cornell University · NIH-11378637 · Data updated 2026-11-12
This grant looks at how polycystic ovary syndrome begins in teenagers and what early signs help doctors diagnose it accurately.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cornell University NIH-funded |
| Lab location | 1 site (Ithaca, United States) |
| Project start | August 1, 2025 |
| Project end | April 30, 2030 |
| Funding year | 2026 |
| Award (this year) | $638,119 |
| NIH project number | 5R01HD117972-02 |
| Project ID | NIH-11378637 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are adolescents (12-20 years old) and young adults (21+ years) who may have or be at risk for PCOS.
✕Less likely to help
Teens without PCOS symptoms or risk factors may not directly benefit from this study.
What this research studies
Polycystic ovary syndrome (PCOS) can start in adolescence, but diagnosing it early is challenging because adolescence has overlapping features with normal puberty. The researchers at Cornell University will study ovarian markers and hormone signals in teens and young adults to see how PCOS progresses over time. They aim to create a clearer picture of the natural history of PCOS during adolescence and how it relates to reproductive and metabolic health. This work could lead to better diagnosis and management strategies for affected teens and young women.
Why it matters
Potential benefit: If successful, this research could lead to earlier, more accurate diagnosis and better management of PCOS in teenagers and young adults.
How similar studies have gone: Preliminary data suggest ovarian morphology and hormones can reflect PCOS severity similarly in adolescents as in adults, supporting the approach.
Where this research is happening
-
Cornell University
Ithaca, United States Active
Researchers
- Principal investigator: Lujan, Marla E — Cornell University
- Study coordinator: Lujan, Marla E
Related research
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Using inositol to improve reproductive and metabolic health in women with PCOS
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A research project at Baylor College of Medicine is studying a genetic variant in SMAD5 that may cause a form of PCOS/PMOS and could lead to new ways to diagnose or treat infertility.
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Genetic clues to PCOS: how genes shape a common women's health condition
A doctor-scientist team at Boston Children’s Hospital is studying how genetic factors contribute to polycystic ovary syndrome (PCOS) across women, men, and children to understand the root causes.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.