Examining how physical activity affects the risk of PCOS in young girls

Investigating the impact of physical activity in modulating PCOS risk among peripubertal females

NIH-funded research Massachusetts General Hospital · NIH-10988317

This study is looking at how physical activity can help girls aged 8 to 10 who are at risk for Polycystic Ovary Syndrome (PCOS) by tracking their insulin and hormone levels while they try out a special exercise program to see if it can improve their health.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10988317 on NIH RePORTER

What this research studies

This research investigates the role of physical activity in reducing the risk of Polycystic Ovary Syndrome (PCOS) among girls aged 8 to 10 who are at risk. It aims to track changes in insulin levels and androgen concentrations as these girls grow, while also testing a tailored physical activity program designed to improve their health outcomes. By using a combination of monitoring techniques and intervention strategies, the study seeks to determine the effectiveness and acceptance of these activities in preventing PCOS. The ultimate goal is to provide evidence-based recommendations for physical activity that can help mitigate the risk of developing PCOS.

Who could benefit from this research

Good fit: Ideal candidates for this research are peripubertal girls aged 8 to 10 who are at risk for developing PCOS.

Not a fit: Patients outside the age range of 8 to 10 years or those not at risk for PCOS may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to effective strategies for preventing PCOS in young girls, improving their long-term health and quality of life.

How similar studies have performed: Previous research has shown promising results in using physical activity as a preventive measure for various health conditions, suggesting potential success for this approach in PCOS prevention.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.