Condition

Kidney Cancer clinical trials and research

• 58Clinical trials
• 34NIH research projects
• 1New in 30 days
• 25Countries

Newest Kidney Cancer clinical trials

All recruiting trials (58)

• Your Kidney Cancer Immunotherapy: How You Get It and If Labs Can Be At Home

  This study tests whether people with kidney cancer prefer intravenous or subcutaneous immunotherapy and whether at‑home lab draws plus telehealth visits before treatment are practical.

  Recruiting at 7 sites Phase 4 Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 6 other locations · NCT07872553

• Perioperative UDCA to Protect Kidney Function in Partial Nephrectomy

  This study tests whether giving ursodeoxycholic acid around surgery can help protect kidney function in adults having partial nephrectomy for kidney tumors.

  Recruiting Phase 2 Jinling Hospital, China · Nanjing, Jiangsu · NCT07672860

• Side Effects and Resource Navigation Program for Cancer Patients

  This program tests whether a navigation service helps adults with kidney, bladder, breast, or lung cancer manage immunotherapy better than usual care.

  Recruiting at 7 sites Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 7 other locations · NCT07646847

• EBNK-001 allogeneic NK cell therapy with low-dose IL-15, with or without pembrolizumab, for advanced solid tumors

  This treatment tests an off-the-shelf NK cell product (EBNK-001) given with low-dose IL-15, either alone or with pembrolizumab, in adults with advanced or metastatic solid tumors who have exhausted standard options.

  Recruiting Phase 1/2 Essen Biotech · Beijing, Beijing Municipality · NCT07410676

• HC-7366 plus nivolumab with or without ipilimumab for advanced clear-cell kidney cancer (SHARK)

  This trial tests whether adding HC-7366 to nivolumab, with or without ipilimumab, can help control advanced clear-cell kidney cancer.

  Recruiting at 2 sites Phase 1 M.D. Anderson Cancer Center · Dallas, Texas and 1 other locations · NCT07401875

• Neoadjuvant HIF-2α inhibitor with or without PD-1 antibody for resectable clear cell kidney cancer

  This trial tests whether casdatifan alone or combined with zimberelimab can shrink tumors in people with resectable clear cell kidney cancer before surgery.

  Recruiting at 2 sites Phase 2 Dana-Farber Cancer Institute · Boston, Massachusetts and 2 other locations · NCT07397611

• Predicting Immunotherapy Response from Live Tumor Biopsies

  This project will try to see if analyzing live tumor biopsy samples kept in their 3D environment can predict whether people with advanced solid tumors will respond to immunotherapy.

  Recruiting at 7 sites Elephas · Fort Smith, Arkansas and 7 other locations · NCT07327489

• Combining sasanlimab, palbociclib, and axitinib for metastatic kidney cancer

  This test tries a combination of sasanlimab, palbociclib, and axitinib in people with advanced or metastatic clear cell or translocation renal cell carcinoma to see if it works and is safe.

  Recruiting at 2 sites Phase 2 Dana-Farber Cancer Institute · Boston, Massachusetts and 1 other locations · NCT07123090

• Virtual exercise program to preserve function and prevent disability during chemotherapy

  This trial tests whether supervised resistance sessions by video plus short home aerobic workouts help adults 18–64 maintain strength and stay active while receiving curative-intent chemotherapy.

  Recruiting at 29 sites Alliance for Clinical Trials in Oncology · Dublin, California and 29 other locations · NCT07059884

• 18F-G1 PET/CT to see early immunotherapy response in solid tumors and blood cancers

  We are testing if the 18F-G1 PET/CT scan can help tell early on whether people with solid tumors or blood cancers will respond to immunotherapy.

  Recruiting Peking University First Hospital · Beijing · NCT07039474

• Visual decision tools to support urologists treating prostate and kidney cancer

  This project will test whether giving urologists visual decision-support tools changes how they talk with patients newly diagnosed with localized prostate or kidney cancer.

  Recruiting UNC Lineberger Comprehensive Cancer Center · Chapel Hill, North Carolina and 1 other locations · NCT06965192

• Nivolumab plus cabozantinib for older adults with kidney cancer

  This trial tests the combination of nivolumab and cabozantinib in people aged 70 and older with metastatic clear-cell kidney cancer to see how it is used and tolerated in routine care.

  Recruiting Phase 4 Gustave Roussy, Cancer Campus, Grand Paris · Angers and 6 other locations · NCT06934057

• Evaluation of a new robotic surgical system for major gastrointestinal and urologic surgeries

  This study is testing a new robotic surgery system to see if it can safely and effectively help patients with major gastrointestinal and urologic conditions like colorectal and prostate cancer.

  Recruiting Chinese University of Hong Kong · Hong Kong · NCT06926374

• Treating the main kidney tumor in metastatic kidney cancer during immunotherapy

  This trial will see if adding surgery or radiotherapy to the main kidney tumor helps people with metastatic clear‑cell kidney cancer who are already benefiting from anti‑PD1–based therapy live longer.

  Recruiting Phase 4 Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Roma · NCT06903312

• Delayed kidney removal after a strong response to immunotherapy for metastatic kidney cancer

  This trial will test whether removing the remaining kidney after a very good response to immunotherapy lets people with metastatic kidney cancer stop systemic treatment and keep the cancer under control.

  Recruiting Institut Paoli-Calmettes · Marseille, Institut Paoli-calmettes · NCT06882486

• Using Ivocizumab to treat various advanced rare tumors

  This study is testing if a new treatment called Ivocizumab can help people with different types of advanced rare tumors feel better and live longer.

  Recruiting Phase 2 Fudan University · Shanghai, Shanghai Municipality · NCT06683846

• Evaluating a new CAR T-cell therapy for solid tumors expressing EGFR

  This study is testing a new CAR T-cell therapy to see if it can safely help adults with certain solid tumors, like colorectal and lung cancer, that have specific markers.

  Recruiting at 10 sites Phase 1/2 A2 Biotherapeutics Inc. · Gilbert, Arizona and 9 other locations · NCT06682793

• Using brodalumab to treat immune-related side effects from cancer therapy

  This study is testing if brodalumab can help cancer patients who are having immune-related side effects from their immunotherapy treatment feel better.

  Recruiting Phase 1 Columbia University · New York, New York · NCT06673329

• Using Riluzole to Help Breast Cancer Survivors with Cognitive Issues

  This study is testing if the medication riluzole can help breast cancer survivors who are having trouble with thinking and memory feel better.

  Recruiting Phase 2 University of California, Irvine · Orange, California · NCT06580002

• Using a digital tool to improve kidney surgery planning

  This study is testing a new digital tool to see if it helps doctors plan kidney surgery better for patients with localized kidney cancer compared to just using regular CT scans.

  Recruiting at 5 sites University Hospital, Ghent · Aalst and 4 other locations · NCT06536439

• Assessing post-operative complications after laparoscopic nephrectomy for kidney cancer

  This study looks at the complications that might happen within a month after patients have outpatient laparoscopic surgery to remove a kidney due to cancer.

  Recruiting GCS Ramsay Santé pour l'Enseignement et la Recherche · Lyon · NCT06532422

• 3D-printed kidney models with realistic tissue stiffness

  We will test whether MRI and ultrasound measurements can predict the stiffness of healthy and cancerous kidney tissue in adults scheduled for nephrectomy.

  Recruiting University Hospital, Bordeaux · Bordeaux · NCT06525831

• Treatment of advanced solid tumors with VET3-TGI immunotherapy

  This study is testing a new cancer treatment called VET3-TGI to see if it can safely target and kill cancer cells in patients with advanced solid tumors, either by injecting it directly into the tumors or giving it through an IV.

  Recruiting at 7 sites Phase 1 KaliVir Immunotherapeutics · Los Angeles, California and 6 other locations · NCT06444815

• Oral Alintegimod with Ipilimumab followed by Nivolumab for advanced cancer

  This study is testing if a new oral medication called Alintegimod, combined with two other cancer treatments, can help people with advanced solid tumors feel better and live longer.

  Recruiting at 4 sites Phase 1/2 7 Hills Pharma, LLC · Aurora, Colorado and 4 other locations · NCT06362369

• Comparing treatments for small kidney tumors

  This study is testing whether a new way to destroy small kidney tumors works better and is safer than traditional surgery for people with localized kidney cancer.

  Recruiting Karolinska University Hospital · Stockholm · NCT06278506

• Precision treatment for kidney cancer based on proteomic analysis

  This study is testing personalized treatment options for kidney cancer patients by grouping them based on their tumor's characteristics to see which combination of drugs works best for them.

  Recruiting Phase 2 Fudan University · Shanghai · NCT06211790

• Using fecal microbiota transplantation to treat diarrhea and colitis from cancer immunotherapy

  This study tests if a stool transplant can help people with melanoma or kidney cancer who are having severe diarrhea and colitis from their immunotherapy treatment.

  Recruiting University of Aarhus · Aarhus N · NCT06206707

• High- vs Low-Intensity Patient Navigation to Increase Patient Participation in Cancer Clinical Programs

  This project tests whether a high-intensity patient navigation program helps adults with prostate or kidney cancer enroll in clinical trials more than a lower-intensity navigation approach.

  Recruiting Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Baltimore, Maryland and 1 other locations · NCT06138067

• MRI-guided radiotherapy for cancer treatment

  This study is testing a new way of giving radiation therapy for cancer that uses MRI technology to better target tumors and improve treatment for patients with different types of cancer.

  Recruiting Hospices Civils de Lyon · Lyon · NCT06041555

• Using advanced MRI techniques to differentiate between benign and malignant kidney masses

  This study is testing advanced MRI techniques to see if they can help doctors tell the difference between harmless and harmful kidney masses, so patients can avoid unnecessary surgeries.

  Recruiting University of Cambridge · Cambridge, Cambridgeshire · NCT06016075

• Combining Pembrolizumab and Axitinib for Kidney Cancer with Tumor Thrombus

  This study is testing whether combining two medications, Pembrolizumab and Axitinib, can help shrink kidney cancer tumors that have spread to a major vein before surgery.

  Recruiting at 3 sites Phase 2 University of Colorado, Denver · Aurora, Colorado and 2 other locations · NCT05969496

• Monitoring kidney cancer using blood tests for DNA changes

  This study is testing if blood tests that look for DNA changes can help track kidney cancer in patients before and after surgery.

  Recruiting Jinling Hospital, China · Nanjing, Jiangsu · NCT05917106

• Using preoperative laxatives to improve recovery after robotic urologic surgery

  This study is testing if taking a laxative before robotic surgery for prostate or kidney cancer can help patients recover better and feel less discomfort afterward.

  Recruiting Phase 4 University of Iowa · Iowa City, Iowa · NCT05805436

• Impact of Exercise and Statins on Cancer Treatment

  This study is testing if doing supervised exercise while taking cancer drugs helps people with metastatic breast, kidney, ovarian, and prostate cancer feel better and respond better to their treatment compared to exercising on their own, and if adding a cholesterol-lowering medication can make it even more effective.

  Recruiting Phase 3 Tampere University Hospital · Tampere, Länsi-Suomi · NCT05796973

• Evaluating surgery's role in metastatic kidney cancer treatment with immunotherapy

  This study is testing if surgery combined with new immune treatments can help people with advanced kidney cancer live longer and feel better.

  Recruiting Yonsei University · Seoul and 2 other locations · NCT05753839

• Testing a microdevice for drug delivery in kidney cancer

  This study is testing a tiny device that delivers small amounts of cancer drugs directly to kidney tumors to see if it helps people with advanced kidney cancer.

  Recruiting Phase 1 Brigham and Women's Hospital · Boston, Massachusetts · NCT05700461

• Biobank for patients with aggressive tumors

  This study is collecting blood and tumor samples from patients with aggressive cancers to see if they can find clues to create better, personalized treatments.

  Recruiting N.N. Petrov National Medical Research Center of Oncology · Saint Petersburg · NCT05539677

• A network for collaborative cancer research in Ontario

  This study is testing a new way to improve cancer treatment by using genetics and technology to help personalize care for people with different types of cancer.

  Recruiting at 2 sites University Health Network, Toronto · Kingston, Ontario and 2 other locations · NCT05403177

• Registry for treatment options of localized kidney tumors

  This study is collecting information from hospitals around the world to see which treatment options work best for people with localized kidney tumors.

  Recruiting at 31 sites Azienda Ospedaliero-Universitaria Careggi · Los Angeles, California and 36 other locations · NCT05363657

• Testing if lab drug screening can predict cancer treatment responses

  This study is testing if a new way of checking how tumors respond to different cancer treatments can help doctors choose the best options for patients with solid tumors like bladder or kidney cancer.

  Recruiting Sheffield Teaching Hospitals NHS Foundation Trust · Sheffield, South Yorkshire · NCT05231655

• Developing a markerless tracking method for real-time tumor motion measurement during radiation therapy

  This study is testing a new way to track tumor movement during radiation therapy without using markers, to see if it can help doctors target the treatment more accurately for cancer patients.

  Recruiting University of Sydney · Saint Leonards, New South Wales and 3 other locations · NCT05184790

• Monitoring drug levels to improve outcomes in metastatic kidney cancer patients

  This study is testing how monitoring drug levels and certain genetic factors can help improve treatment outcomes for people with metastatic kidney cancer.

  Recruiting University of Aarhus · Aarhus, Danmark · NCT04659343

• Understanding how kidney tumors use nutrients for growth

  This study tests how kidney tumors use certain nutrients to grow by giving participants a special nutrient infusion during surgery and checking their blood and tissue samples.

  Recruiting University of Texas Southwestern Medical Center · Dallas, Texas · NCT04623502

• Microwave ablation for treating small kidney and liver tumors

  This study is testing whether microwave ablation can safely and effectively treat small kidney and liver tumors in patients while they continue their regular care.

  Recruiting IRCCS San Raffaele · Milan · NCT03981497

• Deferred surgery for kidney cancer with metastases

  This study is testing whether waiting to do kidney surgery after starting treatment for kidney cancer with metastases can help patients live longer compared to having surgery right away.

  Recruiting at 11 sites University of Aarhus · Aarhus, Central Region of Denmark and 10 other locations · NCT03977571

• Detecting kidney cancer using advanced machine learning techniques

  This study is testing if advanced computer programs can help doctors more accurately spot kidney cancer in CT scans.

  Recruiting Zealand University Hospital · Roskilde · NCT03857373

• Using 3D ultrasound for liver and kidney tumor procedures

  This study tests if using 3D ultrasound during liver and kidney tumor procedures can help doctors see better and improve the results for patients.

  Recruiting Western University, Canada · London, Ontario · NCT03844399

• Monitoring small kidney tumors without immediate treatment

  This study is testing whether closely monitoring small kidney tumors in people over 50 can be a safe alternative to immediate surgery.

  Recruiting IRCCS San Raffaele · Milan · NCT03804320

• Olaparib treatment for patients with metastatic kidney cancer and specific gene mutations

  This study is testing if the oral medication olaparib can help people with advanced kidney cancer who have certain gene mutations and have already tried other treatments.

  Recruiting Phase 2 Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Baltimore, Maryland · NCT03786796

• Developing a liquid biopsy protocol for cancer research at Princess Margaret

  This study is trying to create a simple way to collect blood samples from cancer patients to see if analyzing certain molecules in their blood can help doctors understand their cancer better and track how it changes over time.

  Recruiting University Health Network, Toronto · Toronto, Ontario · NCT03702309

• Evaluating genetic markers in kidney cancer

  This study is testing if certain genetic markers can help us understand kidney cancer better by looking at samples from patients diagnosed with the disease.

  Recruiting Zealand University Hospital · Roskilde · NCT03414827

• French research network for kidney cancer

  This study is trying to gather detailed information and samples from kidney cancer patients in France to see which surgeries and treatments work best for managing the disease.

  Recruiting at 52 sites University Hospital, Bordeaux · Brussels and 67 other locations · NCT03293563

• A resource for collecting cancer data and biospecimens

  This study is creating a resource to collect health information and samples from cancer patients and healthy individuals to help improve cancer prevention and treatment strategies.

  Recruiting at 42 sites University of Nebraska · Greenwood Village, Colorado and 41 other locations · NCT02012699

• Personalized (autologous) and donor (allogeneic) whole-cell vaccine for metastatic tumors

  This will try a vaccine made from a patient's own or donor tumor cells to stimulate the immune system in adults with metastatic cancers and possibly slow disease.

  Recruiting Phase 1/2 Hadassah Medical Organization · Jerusalem · NCT00722228

• Investigating the genetic causes of hereditary kidney cancer

  This study is trying to find out the genetic causes of hereditary kidney cancer to help people with this condition and their families understand their risks and health better.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT00050752

• Genetic analysis of Birt Hogg-Dube syndrome and its link to kidney cancer

  This study is trying to find out the genetic reasons behind Birt Hogg-Dube syndrome and how it relates to kidney cancer in people who have this rare condition and their families.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT00033137

• Collection of blood and tissue samples from patients with suspected or confirmed cancer

  This study is collecting blood and tissue samples from patients with suspected or confirmed cancer to help researchers learn more about how these cancers develop and find new treatment options.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT00026884

• Investigating inherited kidney and urologic cancers

  This study is trying to learn more about inherited kidney and urologic cancers by looking at families with these conditions to see how they develop and what genetic factors are involved.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT00001238

NIH-funded research (34)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Maximizing anti-tumor immune responses in kidney cancer

  A cutting-edge program at UT Southwestern aims to speed up better immunotherapy options for kidney cancer by studying how to activate both innate and adaptive immune responses.

  NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11561063

• Kidney Cancer Career Enhancement Program (CEP) at DF/HCC

  A career-boosting program supports junior investigators studying kidney cancer to help them advance in basic, translational, and clinical work.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11421802

• Kidney Cancer Development Program at DF/HCC

  A funded program at Dana-Farber/Brigham and Women’s Kidney Cancer Center supports new ideas from researchers to improve understanding and treatment of kidney cancer.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11421801

• Personalized antigens for kidney cancer therapy

  This grant explores identifying and targeting tumor-specific antigens in kidney cancer to develop more effective, personalized immunotherapies.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11421800

• Optimizing Anti-PD1 Therapy for High-Risk and Metastatic Kidney Cancer

  A large cancer research grant is testing how best to use anti-PD-1 therapy to help people with high-risk and metastatic kidney cancer live longer and with fewer side effects.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11421799

• Targeting the HIF2 Pathway in Kidney Cancer

  A cancer treatment program aims to see if a drug called belzutifan can help people with a specific kind of kidney cancer whose growth is driven by the HIF2 pathway.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11421798

• Kidney Cancer Tissue Bank and Data Repository Core

  A kidney cancer tissue, blood and clinical data repository core aims to collect, store, and organize samples and linked clinical information to support research and improve care for kidney cancer patients.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11421797

• Kidney cancer biostatistics and bioinformatics support core

  A dedicated biostatistics and bioinformatics core provides expert design, data management, and analysis support for kidney cancer research projects at a leading cancer center.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11421796

• Kidney Cancer SPORE Administrative Core coordinating patient-focused research

  A broad kidney cancer research program at a major Boston center is coordinating science, funding, and patient-facing activities to speed advances and share findings.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11421795

• Kidney Cancer SPORE at Dana-Farber/Harvard Cancer Center

  A large kidney cancer research program is renewing its funding to translate basic discoveries into new patient treatments.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11421794

• UT Southwestern Kidney Cancer SPORE: new approaches to fight renal cancer

  A major kidney cancer program at UT Southwestern is funding bold research to improve treatment for metastatic kidney cancer using targeted drugs, immunotherapy, and new metabolism-based approaches.

  NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11400745

• PFAS exposure and kidney cancer risk in US adults

  This project studies whether exposure to PFAS chemicals is linked to higher risk of kidney cancer in men and women in the United States.

  NIH research Brown University · Providence, United States · NIH-11385958

• Targeting a kidney cancer signaling axis to slow tumor growth

  A new study at UT Southwestern aims to find a more precise way to slow or stop growth of clear cell kidney cancer by focusing on a key cancer signaling pathway.

  NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11381980

• L-2HG and RNA Methylation: A New Path to Kidney Cancer Treatments

  Researchers are studying how a cancer-causing molecule called L-2HG changes RNA in kidney cancer cells and whether this can lead to new treatments for people with advanced renal cell carcinoma.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11369103

• Exosome markers to tell if kidney cancer immunotherapy is working

  We will look for proteins and RNA in blood and urine exosomes to see if they can show early whether immunotherapy helps people with metastatic kidney cancer.

  NIH research Stanford University · Stanford, United States · NIH-11308288

• How kidney cancer hides from the immune system

  Researchers are looking for genetic changes in kidney tumors that let the cancer hide from immune cells in people with clear cell kidney cancer.

  NIH research Emory University · Atlanta, United States · NIH-11299576

• How inherited and tumor DNA changes drive clear cell kidney cancer

  This project looks at how inherited DNA changes and tumor DNA changes work together in people with clear cell kidney cancer to help link genetics and tumor features to treatment decisions.

  NIH research Dana-Farber Cancer Inst · Boston, United States · NIH-11238528

• How VHL gene changes drive clear cell kidney cancer and new ways to target them

  This project is developing new drug approaches that exploit weaknesses in tumors caused by VHL or IDH mutations to help people with clear cell kidney cancer and other cancers with these mutations.

  NIH research Dana-Farber Cancer Inst · Boston, United States · NIH-11173812

• DCLK2–TBK1 signaling as a target in clear cell kidney cancer

  This project aims to find ways to block the DCLK2–TBK1 pathway to slow growth of clear cell kidney cancer, especially tumors that have lost the VHL gene.

  NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11166330

• Boosting immune attack against kidney cancer by activating both innate and adaptive immunity

  This project tries to improve cure rates for people with metastatic kidney cancer who only partially respond to initial immunotherapy by adding focused radiation and a new immune-stimulating drug to standard treatment.

  NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11145087

• UT Southwestern Kidney Cancer Program

  New treatments and scans for people with advanced kidney cancer, including drugs that target HIF2α (even resistant tumors) and therapies that block the cancer's nutrient use.

  NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11145062

• Understanding Kidney Cancer Growth Driven by L-2HG

  This work explores how a molecule called L-2HG helps kidney cancer grow, aiming to find new ways to help patients with advanced disease.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11141123

• Blocking kidney cancer's altered sugar use (the Warburg effect)

  Researchers are testing whether stopping how kidney tumors use sugar for energy can slow or kill renal cell carcinoma.

  NIH research Syracuse VA Medical Center · Syracuse, United States · NIH-11123091

• Identifying early responses to kidney cancer treatment using exosomes

  This study is looking at tiny particles called exosomes in blood and urine to see if they can help doctors tell how well patients with advanced kidney cancer are responding to a combination treatment, so patients can get the right care faster and avoid treatments that aren't working.

  NIH research Stanford University · Stanford, United States · NIH-11114815

• PFAS (forever chemicals) and kidney cancer risk in US adults

  Researchers will compare PFAS chemical levels in people with and without kidney cancer to learn if higher exposure links to cancer risk in US men and women.

  NIH research Brown University · Providence, United States · NIH-11099878

• Investigating how RNA methylation affects kidney cancer progression

  This study is looking at how changes in the SETD2 gene affect kidney cancer, specifically clear cell renal cell carcinoma, to find new ways to treat it better and help patients with personalized therapies.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11061848

• Understanding how kidney cancer cells evade the immune system

  This study is looking at how kidney cancer cells hide from the immune system, especially the important T-cells that help fight cancer, to find ways to make immunotherapy treatments work better for people with clear cell renal cell carcinoma.

  NIH research Emory University · Atlanta, United States · NIH-11061349

• Investigating how metastatic bone disease affects muscle loss in kidney cancer

  This study is looking at how kidney cancer that spreads to the bones can cause severe weight and muscle loss, and it aims to find ways to improve treatment for patients dealing with these tough symptoms.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11055003

• Understanding the genetic changes that lead to kidney cancer.

  This study is looking at how certain genetic changes, both from family and those that happen over time, can influence the growth of clear cell kidney cancer, with the hope of finding better ways to treat patients based on their unique genetic makeup.

  NIH research Dana-Farber Cancer Inst · Boston, United States · NIH-11004978

• Exploring how diet and exercise affect survival in kidney cancer patients

  This study is looking at how healthy eating and staying active can help people with kidney cancer live longer and feel better, so they can make smart choices about their lifestyle during treatment.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-10950992

• Targeting a specific signaling pathway to treat kidney cancer

  This study is looking at a new way to treat clear cell kidney cancer by focusing on a protein called TBK1, which could help create treatments that target cancer cells more effectively while keeping your immune system safe.

  NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-10909301

• Improving kidney cancer treatment using a new vascular therapy

  This study is looking at a new treatment for kidney cancer that targets the unusual blood vessels in tumors to help shrink them, and it aims to see how well this treatment works when used with other existing therapies, giving patients a potential new option to improve their care.

  NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-10871855

• New treatment approach for kidney cancer using a dual inhibitor

  This study is testing a new treatment for clear cell kidney cancer that aims to stop the cancer from growing by using a special drug that targets certain proteins, and it's designed for patients who haven't had success with standard therapies.

  NIH research Kuda Therapeutics, INC. · Salt Lake City, UNITED STATES · NIH-10708992

• Investigating how kidney cancer cells use energy

  This study is looking at how kidney cancer, especially in military personnel and their families, uses different ways to get energy and grow, with the goal of finding better treatments for those affected.

  NIH research Syracuse VA Medical Center · Syracuse, United States · NIH-10701222

Related topics

Quick answers

How many Kidney Cancer clinical trials are recruiting right now?

58, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 25 countries. The most sites are in United States (25 trials), China (7 trials), France (6 trials), Denmark (5 trials), Italy (4 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 8, Phase 1: 4, Phase 4: 4, Phase 1/2: 4. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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