Investigating how kidney cancer cells use energy
Targeting the Warburg Effect in Kidney Cancer
This study is looking at how kidney cancer, especially in military personnel and their families, uses different ways to get energy and grow, with the goal of finding better treatments for those affected.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Syracuse VA Medical Center NIH-funded |
| Lab location | 1 site (Syracuse, United States) |
| Project ID | NIH-10701222 on NIH RePORTER |
What this research studies
This research focuses on understanding the Warburg Effect in kidney cancer, particularly clear cell renal cell carcinoma (ccRCC), which is known for its resistance to traditional treatments. The study aims to explore the unique metabolic pathways that cancer cells utilize to thrive, especially in military personnel and their families who may be at higher risk due to environmental exposures. By analyzing the biological mechanisms behind this cancer, the research seeks to identify new therapeutic strategies that could improve treatment outcomes for patients. The approach includes biochemical assays and cellular studies to uncover how these cancer cells manage energy production.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with clear cell renal cell carcinoma, particularly those with a history of military service or exposure to known risk factors.
Not a fit: Patients with other types of kidney cancer or those who do not have clear cell renal cell carcinoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for kidney cancer, improving survival rates and quality of life for patients.
How similar studies have performed: Previous research has shown promise in targeting metabolic pathways in cancer treatment, suggesting that this approach could yield significant advancements.
Where this research is happening
Syracuse, United States
- Syracuse VA Medical Center — Syracuse, United States (Active)
Researchers
- Principal investigator: Mollapour, Mehdi — Syracuse VA Medical Center
- Study coordinator: Mollapour, Mehdi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.