Detecting kidney cancer using advanced machine learning techniques
Official title: Renal Cancer Detection Using Convolutional Neural Networks
Run by Zealand University Hospital · NCT03857373 · Data updated 2026-11-12
This study is testing if advanced computer programs can help doctors more accurately spot kidney cancer in CT scans.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | Zealand University Hospital Academic / other |
| Locations | 1 site (Roskilde) |
| Status | Recruiting |
| Started | February 1, 2019 |
| Main results expected | January 1, 2025 |
| Study ends | January 1, 2027 |
| Registry record updated | January 30, 2024 |
| Trial ID | NCT03857373 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients diagnosed with renal cell carcinoma (RCC) who have undergone surgical treatment.
✕Probably not a fit
Patients with RCC who have not undergone surgery may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project focuses on utilizing deep learning architectures, specifically convolutional neural networks (CNN), to enhance the accuracy of computer-aided diagnosis (CAD) systems for renal cancer detection. The study aims to classify renal tumors from CT urography scans into various categories, including cancerous and non-cancerous types, while minimizing false positives. By automating the detection process, the study seeks to significantly reduce the time required for radiologists to create large-scale labeled datasets, ultimately improving diagnostic efficiency and accuracy.
Why it matters
Potential benefit: If successful, this approach could lead to faster and more accurate diagnoses of kidney cancer, improving patient outcomes.
How similar studies have gone: Other studies utilizing machine learning for cancer detection have shown promising results, indicating potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patient with RCC, who underwent surgery Exclusion Criteria: * Patients with RCC, who did not underwent surgery
Where it's running
-
Zealand University Hospital
Roskilde, Denmark Recruiting
Study contacts
- Study coordinator: Nessn Azawi, Phd
- Email: nesa@regionsjaelland.dk
- Phone: 004526393034
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Your Kidney Cancer Immunotherapy: How You Get It and If Labs Can Be At Home
This study tests whether people with kidney cancer prefer intravenous or subcutaneous immunotherapy and whether at‑home lab draws plus telehealth visits before treatment are practical.
-
Perioperative UDCA to Protect Kidney Function in Partial Nephrectomy
This study tests whether giving ursodeoxycholic acid around surgery can help protect kidney function in adults having partial nephrectomy for kidney tumors.
-
Side Effects and Resource Navigation Program for Cancer Patients
This program tests whether a navigation service helps adults with kidney, bladder, breast, or lung cancer manage immunotherapy better than usual care.
-
EBNK-001 allogeneic NK cell therapy with low-dose IL-15, with or without pembrolizumab, for advanced solid tumors
This treatment tests an off-the-shelf NK cell product (EBNK-001) given with low-dose IL-15, either alone or with pembrolizumab, in adults with advanced or metastatic solid tumors who have exhausted standard options.
-
HC-7366 plus nivolumab with or without ipilimumab for advanced clear-cell kidney cancer (SHARK)
This trial tests whether adding HC-7366 to nivolumab, with or without ipilimumab, can help control advanced clear-cell kidney cancer.
-
Neoadjuvant HIF-2α inhibitor with or without PD-1 antibody for resectable clear cell kidney cancer
This trial tests whether casdatifan alone or combined with zimberelimab can shrink tumors in people with resectable clear cell kidney cancer before surgery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.