Clinical trial Recruiting at 31 sites Observational Ages 18 and up

Registry for treatment options of localized kidney tumors

Official title: International REgistry of COnservative or Radical Treatment of Localized Kidney Tumors (i-RECORd)

Run by Azienda Ospedaliero-Universitaria Careggi · NCT05363657 · Data updated 2026-11-12

This study is collecting information from hospitals around the world to see which treatment options work best for people with localized kidney tumors.

More Kidney Cancer trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment10000 (estimated)
SponsorAzienda Ospedaliero-Universitaria Careggi
Academic / other
Locations37 sites (Los Angeles, California and 36 other locations)
StatusRecruiting
StartedJanuary 10, 2022
Main results expectedDecember 31, 2023
Study endsDecember 31, 2028
Registry record updatedMay 6, 2022
Trial IDNCT05363657 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults aged 18 and older with a radiological diagnosis of a renal tumor that is suitable for active treatment or active surveillance.

Probably not a fit

Patients with urothelial renal carcinoma or those who refuse to participate in clinical research may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational registry collects data on the management of kidney cancer from 50 high-volume tertiary referral centers worldwide over a two-year period, with a five-year follow-up. It aims to evaluate various treatment approaches, including partial nephrectomy, radical nephrectomy, ablation techniques, and active surveillance, to determine the best personalized strategies for patients with localized renal tumors. The study will utilize a web-based platform for data collection, ensuring comprehensive and standardized information gathering from participating centers.

Why it matters

Potential benefit: If successful, this registry could help identify the most effective treatment strategies for localized kidney tumors, leading to improved patient outcomes.

How similar studies have gone: Other studies have shown success with similar observational approaches in cancer management, indicating potential for valuable insights from this registry.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Radiological diagnosis of renal tumor susceptible to active treatment or AS/WW.
* Age ≥18 years
* Informed consent signed

Exclusion Criteria:

* Patient refuse to participate in clinical research.
* Urothelial renal carcinoma.

Where it's running

  • Institute of Urology, University of Southern California.
    Los Angeles, California, United States
    Recruiting
  • University of California San Diego, Moores Cancer Center
    San Diego, California, United States
    Recruiting
  • VCU Health System
    Richmond, Virginia, United States
    Recruiting
  • Medical University of Vienna, Vienna General Hospital
    Vienna, Austria
    Recruiting
  • University of Bruxelles
    Brussels, Belgium
    Recruiting
  • Onze Lieve Vrouw Hospital
    Leuven, Belgium
    Recruiting
Show 31 more locations
  • Santa Casa da Misericórdia de Fortaleza
    Fortaleza, Brazil
    Recruiting
  • University of Patras
    Pátrai, Greece
    Recruiting
  • Urology, Andrology & Kidney Transplantation Unit, University of Bari
    Bari, Italy
    Recruiting
  • Policlinico S. Orsola Malpighi
    Bologna, Italy
    Recruiting
  • Department of Urology, University of Florence, Unit of Oncologic Minimally-Invasive Urology and Andrology, Careggi Hospital
    Florence, Italy
    Recruiting
  • Policlinico Riuniti, Università di Foggia.
    Foggia, Italy
    Recruiting
  • Division of Urology, University of Genoa,Policlinico San Martino Hospital
    Genova, Italy
    Recruiting
  • Azienda Ospedaliera Policlinico "G. Martino", Università di Messina.
    Messina, Italy
    Recruiting
  • San Raffaele Scientific Institute, Milan, Italy; Division of Experimental Oncology/Unit of Urology, URI, IRCCS San Raffaele Hospital
    Milan, Italy
    Recruiting
  • Policlinico Istituto Europeo di Oncologia (IEO)
    Milan, Italy
    Recruiting
  • Istituto Nazionale dei Tumori Fondazione Senatore "G. Pascale"
    Naples, Italy
    Recruiting
  • Institute Oncology Veneto (IOV)
    Padova, Italy
    Recruiting
  • Humanitas Hospital
    Rozzano, Italy
    Recruiting
  • Università degli Studi di Torino, Ospedale S. Luigi Gonzaga.
    Torino, Italy
    Recruiting
  • Università degli studi di Torino, Ospedale Molinette
    Torino, Italy
    Recruiting
  • AOUI Verona
    Verona, Italy
    Recruiting
  • Amsterdam University Medical Centers
    Amsterdam, Netherlands
    Recruiting
  • European Health Center
    Otwock, Poland
    Recruiting
  • Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie
    Warsaw, Poland
    Recruiting
  • N.N. Blokhin National Medical Research Center of Oncology
    Moscow, Russia
    Recruiting
  • NG Teng Fong General Hospital
    Singapore, Singapore
    Recruiting
  • Fundaciò Puigvert
    Barcelona, Spain
    Recruiting
  • Hospital Universitario Ramón y Cajal, University of Alcalá
    Madrid, Spain
    Recruiting
  • Bristol Urological Institute
    Bristol, United Kingdom
    Recruiting
  • Guy's Hospital
    London, United Kingdom
    Recruiting
  • Stanford University
    Stanford, California, United States
    Not yet recruiting
  • Loyola University Medical Center, Edward Hines VA Hospital
    Chicago, Illinois, United States
    Not yet recruiting
  • University of Pennsylvania
    Philadelphia, Pennsylvania, United States
    Not yet recruiting
  • Swedish Hospital
    Seattle, Washington, United States
    Not yet recruiting
  • University Hospitals Leuven
    Leuven, Belgium
    Not yet recruiting
  • Jikei University School of Medicine
    Tokyo, Japan
    Not yet recruiting

Study contacts

  • Principal investigator: Andrea Minervini, Prof. — Dipartimento di Medicina Clinica e Sperimentale Via o Piazza Largo Brambilla 3 - 50134 Firenze (Italy)
  • Study coordinator: Marco Carini, Prof.
  • Email: carini@unifi.it
  • Phone: 055 794 6351

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.