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Registry for treatment options of localized kidney tumors

International REgistry of COnservative or Radical Treatment of Localized Kidney Tumors (i-RECORd)

Azienda Ospedaliero-Universitaria Careggi · NCT05363657

This study is collecting information from hospitals around the world to see which treatment options work best for people with localized kidney tumors.

Quick facts

Study typeObservational
Enrollment10000 (estimated)
Ages18 Years and up
SexAll
SponsorAzienda Ospedaliero-Universitaria Careggi (other)
Locations37 sites (Los Angeles, California and 36 other locations)
Trial IDNCT05363657 on ClinicalTrials.gov

What this trial studies

This observational registry collects data on the management of kidney cancer from 50 high-volume tertiary referral centers worldwide over a two-year period, with a five-year follow-up. It aims to evaluate various treatment approaches, including partial nephrectomy, radical nephrectomy, ablation techniques, and active surveillance, to determine the best personalized strategies for patients with localized renal tumors. The study will utilize a web-based platform for data collection, ensuring comprehensive and standardized information gathering from participating centers.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older with a radiological diagnosis of a renal tumor that is suitable for active treatment or active surveillance.

Not a fit: Patients with urothelial renal carcinoma or those who refuse to participate in clinical research may not benefit from this study.

Why it matters

Potential benefit: If successful, this registry could help identify the most effective treatment strategies for localized kidney tumors, leading to improved patient outcomes.

How similar studies have performed: Other studies have shown success with similar observational approaches in cancer management, indicating potential for valuable insights from this registry.

Eligibility criteria

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Radiological diagnosis of renal tumor susceptible to active treatment or AS/WW.
* Age ≥18 years
* Informed consent signed

Exclusion Criteria:

* Patient refuse to participate in clinical research.
* Urothelial renal carcinoma.

Where this trial is running

Los Angeles, California and 36 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Kidney Cancer, Kidney cancer, Partial Nephrectomy, Radical Nephrectomy, Ablation Techniques, Active Surveillance, Recurrence Free Survival, Watchful Waiting

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.