Evaluating genetic markers in kidney cancer
Official title: Genetic Evaluation of Renal Cell Carcinoma; Predicting Biomarkers for Renal Cell Carcinoma
Run by Zealand University Hospital · NCT03414827 · Data updated 2026-11-12
This study is testing if certain genetic markers can help us understand kidney cancer better by looking at samples from patients diagnosed with the disease.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 120 (estimated) |
| Sponsor | Zealand University Hospital Academic / other |
| Locations | 1 site (Roskilde) |
| Status | Recruiting |
| Started | February 1, 2019 |
| Main results expected | December 1, 2025 |
| Study ends | December 1, 2027 |
| Registry record updated | January 30, 2024 |
| Trial ID | NCT03414827 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed with renal cell carcinoma.
✕Probably not a fit
Patients without signs of malignancy or those who are incapacitated may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to recruit participants diagnosed with renal cell carcinoma to evaluate genetic biomarkers associated with the disease. Initially, 10 patients will be recruited from the urological department at Zealand University Hospital, followed by the analysis of biological materials from an additional 100 patients sourced from the national Biobank. The final phase will involve a gene test on 10 selected patients to further investigate the genetic aspects of kidney cancer.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and potential new biomarkers for kidney cancer, enhancing diagnosis and treatment strategies.
How similar studies have gone: While similar studies have explored genetic evaluations in cancer, this specific approach is novel and aims to identify biomarkers for kidney cancer.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who have been diagnosed with kidney cancer. Exclusion Criteria: * Patients without signs of malignancy at final histology report. * Incapacitated patients.
Where it's running
-
Zealand University Hospital
Roskilde, Denmark Recruiting
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Your Kidney Cancer Immunotherapy: How You Get It and If Labs Can Be At Home
This study tests whether people with kidney cancer prefer intravenous or subcutaneous immunotherapy and whether at‑home lab draws plus telehealth visits before treatment are practical.
-
Perioperative UDCA to Protect Kidney Function in Partial Nephrectomy
This study tests whether giving ursodeoxycholic acid around surgery can help protect kidney function in adults having partial nephrectomy for kidney tumors.
-
Side Effects and Resource Navigation Program for Cancer Patients
This program tests whether a navigation service helps adults with kidney, bladder, breast, or lung cancer manage immunotherapy better than usual care.
-
EBNK-001 allogeneic NK cell therapy with low-dose IL-15, with or without pembrolizumab, for advanced solid tumors
This treatment tests an off-the-shelf NK cell product (EBNK-001) given with low-dose IL-15, either alone or with pembrolizumab, in adults with advanced or metastatic solid tumors who have exhausted standard options.
-
HC-7366 plus nivolumab with or without ipilimumab for advanced clear-cell kidney cancer (SHARK)
This trial tests whether adding HC-7366 to nivolumab, with or without ipilimumab, can help control advanced clear-cell kidney cancer.
-
Neoadjuvant HIF-2α inhibitor with or without PD-1 antibody for resectable clear cell kidney cancer
This trial tests whether casdatifan alone or combined with zimberelimab can shrink tumors in people with resectable clear cell kidney cancer before surgery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.