Comparing treatments for small kidney tumors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to compare the effectiveness and safety of ablative treatments versus surgical resection for small kidney tumors. It will evaluate complications, tumor recurrence, kidney function, quality of life, and health economic factors in patients with localized kidney cancer. Participants will be randomly assigned to receive either treatment, and their outcomes will be monitored to determine which approach is more beneficial. The study addresses a gap in existing research by directly comparing these two treatment modalities.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 - 99 years
* Patient suitable based on clinical status for both ablative treatment and surgery
* Primary kidney tumor
* Tumor size ≤ 3 cm
* Clinical stage of the tumor T1a (no macroscopic vascular or extrarenal invasion)
* Tumor location suitable for both ablative treatment and resection
* Absence of radiological signs of metastasis
* Biopsy with malignant pathological analysis (PAD)
* ISUP grade I-III"

Exclusion Criteria:

* Radiological signs of metastasis
* Synchronous kidney tumors
* ISUP grade IV or sarcomatoid growth in the biopsy
* Other metastasized cancer in the last 5 years
* Patient unable to make an informed decision to participate in the study

Where it's running

• Karolinska University Hospital
  Stockholm, Sweden Recruiting

Study contacts

• Principal investigator: Anders Kjellman, MD, PhD — Karolinska University Hospital
• Study coordinator: Anders Kjellman, MD, PhD
• Email: anders.kjellman@regionstockholm.se
• Phone: +46736995258

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.