Condition

Hidradenitis Suppurativa clinical trials and research

• 31Clinical trials
• 27NIH research projects
• 32Countries

Newest Hidradenitis Suppurativa clinical trials

All recruiting trials (31)

• BTK inhibitor remibrutinib in hidradenitis suppurativa shows how it works in adults

  This phase 1 trial tests whether remibrutinib can safely affect HS in adults with moderate to severe disease.

  Recruiting at 2 sites Phase 1 Novartis · San Diego, California and 1 other locations · NCT07855276

• Olatorepatide vs placebo for adults with moderate-to-severe hidradenitis suppurativa who are overweight

  This study tests whether olatorepatide can help people with hidradenitis suppurativa who are overweight or obese.

  Recruiting Phase 2 Regeneron Pharmaceuticals · The Bronx, New York · NCT07830329

• Remibrutinib extension study for adults with moderate to severe hidradenitis suppurativa

  This extension study tests whether continuing remibrutinib is safe and helps skin symptoms in adults who completed prior HS trials.

  Recruiting at 61 sites Phase 3 Novartis · Birmingham, Alabama and 60 other locations · NCT07665437

• LAD328 in adults with hidradenitis suppurativa

  This study tests whether LAD328 works better than placebo for adults with moderate-to-severe hidradenitis suppurativa.

  Recruiting Phase 2 Almirall, S.A. · Warsaw, Masovian Voivodeship · NCT07547813

• Long-term real-world tracking of secukinumab treatment for moderate to severe hidradenitis suppurativa in Italy

  This project will see how secukinumab works and is used in adults with moderate to severe hidradenitis suppurativa in Italy.

  Recruiting at 16 sites Novartis · Ancona, AN and 15 other locations · NCT07543419

• Secukinumab outcomes in Canadians with hidradenitis suppurativa

  It will see how well secukinumab works and how safe it is for adults in Canada with moderate-to-severe hidradenitis suppurativa who were newly prescribed it in routine care.

  Recruiting at 15 sites Novartis · Calgary, Alberta and 14 other locations · NCT07282015

• Post-marketing surveillance of Cosentyx (secukinumab) for hidradenitis suppurativa, pediatric plaque psoriasis, and juvenile idiopathic arthritis in Korea

  This study will see how Cosentyx (secukinumab) works and is tolerated in people in Korea with moderate-to-severe hidradenitis suppurativa, pediatric plaque psoriasis, or juvenile idiopathic arthritis who are being treated in routine care.

  Recruiting Novartis · Seoul, Seoul · NCT07243782

• SAR445399 treatment for adults with moderate to severe hidradenitis suppurativa

  This will test two doses of SAR445399 versus placebo in adults with moderate to severe hidradenitis suppurativa to see if it reduces abscesses and inflammatory nodules and is safe.

  Recruiting at 85 sites Phase 2 Sanofi · Scottsdale, Arizona and 85 other locations · NCT07225569

• Brivekimig for moderate to severe hidradenitis suppurativa

  This trial will test whether brivekimig can reduce symptoms in people with moderate to severe hidradenitis suppurativa.

  Recruiting at 77 sites Phase 2 Sanofi · Phoenix, Arizona and 84 other locations · NCT07170917

• LAD191 for adults with moderate-to-severe hidradenitis suppurativa

  This trial will try different doses of LAD191 to see if it reduces lesions and symptoms in adults with moderate-to-severe hidradenitis suppurativa compared with placebo and adalimumab.

  Recruiting Phase 2 Almirall, S.A. · Manises · NCT07151937

• Global assessment of disease burden in adolescents and adults with alopecia areata, vitiligo, or hidradenitis suppurativa

  This project will see if collecting real-world information from adolescents and adults with moderate or severe alopecia areata, non-segmental vitiligo, or hidradenitis suppurativa can describe their disease burden worldwide.

  Recruiting at 116 sites AbbVie · Ciudad Autonoma de Buenos Aire, Buenos Aires and 115 other locations · NCT07136467

• Maximal-use ruxolitinib cream for adults and teens with hidradenitis suppurativa

  This trial will test whether applying ruxolitinib cream over large skin areas is safe and tolerable in adults and adolescents with hidradenitis suppurativa.

  Recruiting at 16 sites Phase 1 Incyte Corporation · Phoenix, Arizona and 20 other locations · NCT07049575

• Evaluating HB0043 for treating Hidradenitis Suppurativa

  This study is testing a new treatment called HB0043 to see if it helps adults with moderate to severe Hidradenitis Suppurativa feel better and stay safe during the process.

  Recruiting Phase 1/2 Shanghai Huaota Biopharmaceutical Co., Ltd. · Jinan, Shandong · NCT06895499

• Assessing Bimekizumab Levels in Breast Milk of Nursing Mothers

  This study tests how much of the medication bimekizumab is found in the breast milk of mothers who have been using it for at least 12 weeks after giving birth to see if it's safe for their babies.

  Recruiting at 14 sites Phase 1 UCB Pharma · Santa Monica, California and 13 other locations · NCT06888193

• Comparing secukinumab and tofacitinib for treating hidradenitis suppurativa in Chinese patients

  This study is testing whether secukinumab or tofacitinib works better for treating moderate to severe hidradenitis suppurativa in Chinese adults.

  Recruiting Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou, Zhejiang · NCT06707246

• Biomarkers that predict how skin-disease treatments will work

  Researchers are testing blood and skin markers to see if they can forecast which patients with inflammatory skin diseases will respond to systemic treatments over a year.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT06599411

• Assessing molecular changes in adults with moderate to severe skin conditions receiving Lutikizumab

  This study is testing a new drug called Lutikizumab to see if it can help adults with moderate to severe skin conditions like hidradenitis suppurativa and atopic dermatitis feel better.

  Recruiting at 2 sites Phase 2 AbbVie · Sacramento, California and 1 other locations · NCT06524635

• Bacteriophage therapy for hard-to-treat infections

  This study is testing if a new treatment using bacteriophages can help people with tough infections that don’t respond to regular medicines.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven · NCT06368388

• Evaluating Siplizumab for Hidradenitis Suppurativa Treatment

  This study is testing whether a new medication called siplizumab can help people with moderate to severe Hidradenitis Suppurativa who haven't found relief with other treatments.

  Recruiting Early Phase 1 University of Alabama at Birmingham · Birmingham, Alabama · NCT06326476

• Capsule microbiota transplant therapy for hidradenitis suppurativa

  This study is testing whether taking a special gut treatment can help adults with hidradenitis suppurativa feel better by improving their skin condition.

  Recruiting Early Phase 1 University of Minnesota · Minneapolis, Minnesota · NCT06058520

• Collecting samples from people with skin conditions and healthy volunteers

  This study is collecting samples from people with different skin conditions and healthy volunteers to see how their biology differs and learn more about these conditions.

  Recruiting Innovaderm Research Inc. · Montreal, Quebec · NCT05994976

• Understanding the factors influencing chronic inflammatory skin diseases

  This study is trying to understand what causes different types of chronic skin conditions, like eczema and psoriasis, to behave differently in patients over time.

  Recruiting University Hospital Schleswig-Holstein · Kiel · NCT05928169

• Adapted antibiotic treatment for Hurley stage 2 hidradenitis suppurativa

  This trial tests whether a tailored sequence of antibiotics works better than 12 weeks of lymecycline for adults under 60 with active Hurley stage 2 hidradenitis suppurativa.

  Recruiting Phase 3 Institut Pasteur · Marseille and 3 other locations · NCT05821478

• Investigating the role of hair follicle stem cells in Hidradenitis Suppurativa

  This study is trying to understand how hair follicle stem cells might be involved in Hidradenitis Suppurativa to help find better treatments for people with this condition.

  Recruiting Assistance Publique - Hôpitaux de Paris · Créteil, Val-de-marne · NCT05531747

• Examining inflammatory genes in patients with hidradenitis suppurativa

  This study is trying to see if certain inflammatory genes are different in people with hidradenitis suppurativa compared to healthy individuals, and it also looks at how childhood trauma might affect this skin condition.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT05507125

• Using botulinum toxin to treat Hidradenitis Suppurativa

  This study is testing if botulinum toxin can help reduce inflammation and improve symptoms in people with Hidradenitis Suppurativa.

  Recruiting University of Massachusetts, Worcester · Worcester, Massachusetts · NCT05403710

• Registry for soft tissue reconstruction using Myriad™ devices

  This study is testing how safe and effective Myriad Matrix™ and Morcells™ devices are for people undergoing soft tissue reconstruction surgeries for different conditions.

  Recruiting at 6 sites Aroa Biosurgery Limited · Phoenix, Arizona and 14 other locations · NCT05243966

• Using battlefield acupuncture to relieve pain in hidradenitis suppurativa

  This study is testing if battlefield acupuncture can help reduce pain for people with hidradenitis suppurativa.

  Recruiting Wayne State University · Dearborn, Michigan · NCT04218422

• Registry and biospecimen collection for hidradenitis suppurativa

  This study is collecting information from people with hidradenitis suppurativa to better understand the condition and find new treatment options.

  Recruiting University of California, San Francisco · San Francisco, California · NCT04115566

• Understanding the characteristics of Hidradenitis Suppurativa

  This study is trying to better understand the symptoms and biological features of Hidradenitis Suppurativa to help find better ways to treat people with this skin condition.

  Recruiting University of California, San Francisco · San Francisco, California · NCT03967600

• Creating a biorepository for studying inflammatory skin disorders

  This study is trying to collect and analyze samples from people with and without inflammatory skin disorders to better understand these conditions and help find new treatments.

  Recruiting Ohio State University · Columbus, Ohio · NCT03146676

NIH-funded research (27)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Anti-CD38 immunotherapy for severe hidradenitis suppurativa

  A new treatment using anti-CD38 therapy is being tested for people with severe hidradenitis suppurativa who have not responded to prior therapies.

  NIH research Henry Ford Health + Michigan State University Health Sciences · East Lansing, United States · NIH-11526578

• Botulinum toxin blocks nerve signals to immune cells to treat hidradenitis suppurativa

  This NIH grant tests a new approach to hidradenitis suppurativa by using botulinum toxin to interrupt nerve signals that may drive skin inflammation in patients.

  NIH research Univ of Massachusetts Med Sch Worcester · Worcester, United States · NIH-11448989

• Precision therapies for hidradenitis suppurativa using AI

  A doctor-researcher team at UC San Francisco is using advanced computer methods to find personalized drug options to treat hidradenitis suppurativa.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11436909

• Injectable Hydrogel for HS: a localized therapy to ease painful skin disease

  A new baricitinib hydrogel is being developed to deliver pain relief and reduce inflammation directly in hidradenitis suppurativa (HS) lesions, potentially lowering systemic side effects.

  NIH research Incuta Therapeutics LLC · Philadelphia, United States · NIH-11407993

• Whole-genome sequencing to understand hidradenitis suppurativa in diverse groups

  Researchers will study the genetic factors that contribute to hidradenitis suppurativa, especially in African American, Hispanic/Latino, and White patients, to better understand why some people are more affected.

  NIH research Henry Ford Health + Michigan State University Health Sciences · East Lansing, United States · NIH-11404883

• Understanding the Genes Behind Hidradenitis Suppurativa in teens and young adults

  A study to find genetic factors that contribute to hidradenitis suppurativa (HS), a painful skin condition that often starts in adolescence and affects many Black individuals.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11401412

• Cortisol Synthesis and HS Tunnel Disease in 3D Skin Models

  Aims to understand how cortisol production and signaling affect the painful tunnels in hidradenitis suppurativa using 3D skin models and patient tissue.

  NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11382177

• Modeling HS: how genes linked to hidradenitis suppurativa drive disease

  A small NIH grant is exploring how genetic factors linked to hidradenitis suppurativa may cause skin inflammation and lesions in adults, with potential to guide better treatments.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11372358

• Photoacoustic and ultrasound imaging to better measure hidradenitis suppurativa

  This project tries a new imaging method that combines photoacoustic and ultrasound scans to better see and measure disease in people with hidradenitis suppurativa.

  NIH research University of Illinois at Chicago · Chicago, UNITED STATES · NIH-11266156

• Immune signals in African American women with hidradenitis suppurativa

  This project looks at genetic and immune differences linked to hidradenitis suppurativa in African American women to help explain why the disease is more severe in some groups.

  NIH research Henry Ford Health + Michigan State University Health Sciences · East Lansing, United States · NIH-11261988

• Genetics of hidradenitis suppurativa in diverse populations

  Researchers will use whole-genome sequencing to find genetic differences that might explain why hidradenitis suppurativa affects some people, especially African American and Hispanic/Latino patients, more severely.

  NIH research Henry Ford Health + Michigan State University Health Sciences · East Lansing, United States · NIH-11195106

• Cortisol and tunnel formation in hidradenitis suppurativa

  This project looks at whether low local cortisol activity in skin contributes to the formation and inflammation of tunnels in people with hidradenitis suppurativa.

  NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11181318

• Finding the genes behind hidradenitis suppurativa

  This project will look for genetic changes linked to hidradenitis suppurativa by studying DNA and skin samples from people with the condition.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11175361

• Understanding genetic roots of hidradenitis suppurativa in African Americans

  A research team at NYU aims to find genetic factors that contribute to hidradenitis suppurativa, focusing on African American people who are disproportionately affected, to help guide future treatments.

  NIH research New York University School of Medicine · New York, United States · NIH-11171792

• Understanding the role of gamma secretase in a skin condition called hidradenitis suppurativa.

  This study is looking into hidradenitis suppurativa, a painful skin condition, to understand how a protein called gamma secretase might be affecting it, especially in people who don't have known genetic issues, with the hope of finding better treatments for those who struggle with this condition.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11161854

• Understanding the genetic causes of hidradenitis suppurativa in African Americans

  This study is looking at the genes that might cause hidradenitis suppurativa, a painful skin condition, especially in African Americans who are affected more than others, to help find better treatments and care for everyone dealing with this issue.

  NIH research New York University School of Medicine · New York, United States · NIH-11159205

• Genetics of hidradenitis suppurativa across diverse racial groups

  This project looks for genetic differences linked to hidradenitis suppurativa in people from European, African American, and Asian backgrounds to help point to new treatment targets.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11158940

• Identifying different types of hidradenitis suppurativa

  This study is looking at hidradenitis suppurativa (HS) to find different types of the condition, which will help doctors give better diagnoses and treatments, and it's for anyone living with HS who wants to help improve care for themselves and others.

  NIH research New York University School of Medicine · New York, United States · NIH-11146921

• Understanding Immune Cells in Hidradenitis Suppurativa Skin

  This project aims to understand how immune cells in the skin of people with hidradenitis suppurativa contribute to the condition, especially looking at how a common virus might be involved.

  NIH research Emory University · Atlanta, United States · NIH-11140543

• Reducing inflammation in a painful skin condition called hidradenitis suppurativa

  This study is looking at how certain nerve cells in the skin can cause inflammation in hidradenitis suppurativa (HS), and it aims to find new treatments that can help reduce this inflammation and pain, with the possibility of involving patients in trials to test these new options.

  NIH research Univ of Massachusetts Med Sch Worcester · Worcester, United States · NIH-11078296

• Improving imaging techniques for diagnosing and evaluating hidradenitis suppurativa

  This study is looking to improve how we diagnose and plan treatment for hidradenitis suppurativa (HS) by using new imaging techniques that can spot important signs of the condition that regular methods might miss, helping patients find better treatments faster.

  NIH research University of Illinois at Chicago · Chicago, UNITED STATES · NIH-11056755

• Analyzing the genetic factors of hidradenitis suppurativa

  This study is looking at how genetics might play a role in hidradenitis suppurativa, a painful skin condition, by comparing samples from African American, Hispanic/Latino, and White patients to understand why the disease affects different groups in different ways, and your participation could help us learn more about i

  NIH research Henry Ford Health + Michigan State University Health Sciences · East Lansing, United States · NIH-10981631

• Understanding the genetic causes of hidradenitis suppurativa

  This study is looking at how genes might play a role in hidradenitis suppurativa (HS), a skin condition that can really affect young people's lives, and it involves gathering blood samples from around 2,000 patients to find new genetic clues that could lead to better treatments.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-10981410

• Investigating how cortisol affects the formation of tunnels in Hidradenitis suppurativa

  This study is looking at how a hormone called cortisol affects the painful skin tunnels that people with Hidradenitis suppurativa (HS) experience, using a special 3D model to help find better treatments for this condition.

  NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-10980978

• Understanding factors affecting racial and socioeconomic disparities in hidradenitis suppurativa

  This study is looking into hidradenitis suppurativa, a painful skin condition that affects many people, especially in different racial and ethnic groups, to understand what makes it more common and how to improve treatment options for everyone dealing with it.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-10927395

• Understanding the genetic factors of hidradenitis suppurativa across different races

  This study is looking into hidradenitis suppurativa, a painful skin condition that affects people of different backgrounds, to better understand its causes and find new ways to treat it by comparing the genetics of those with the condition to healthy individuals.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-10889138

• Understanding pain in hidradenitis suppurativa and improving treatment options

  This study is looking at how pain affects people with hidradenitis suppurativa and aims to find better ways to help manage that pain and improve their daily lives, with input from both patients and doctors.

  NIH research Emory University · Atlanta, United States · NIH-10876491

Related topics

Quick answers

How many Hidradenitis Suppurativa clinical trials are recruiting right now?

31, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 32 countries. The most sites are in United States (17 trials), Canada (7 trials), France (7 trials), Germany (6 trials), Spain (6 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 6, Phase 1: 3, Phase 3: 2, Early Phase 1: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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