Reducing inflammation in a painful skin condition called hidradenitis suppurativa
Targeting cutaneous nociceptors to reduce Type-17 inflammation in hidradenitis suppurativa
This study is looking at how certain nerve cells in the skin can cause inflammation in hidradenitis suppurativa (HS), and it aims to find new treatments that can help reduce this inflammation and pain, with the possibility of involving patients in trials to test these new options.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Massachusetts Med Sch Worcester NIH-funded |
| Lab location | 1 site (Worcester, United States) |
| Project ID | NIH-11078296 on NIH RePORTER |
What this research studies
This research focuses on understanding and targeting specific nerve cells in the skin that contribute to inflammation in hidradenitis suppurativa (HS), a chronic skin condition. The approach involves using advanced techniques to analyze immune cells in affected skin and testing treatments that block pain signals to reduce inflammation. By studying how certain neuropeptides influence immune responses, the research aims to develop new therapeutic strategies for managing HS. Patients may be involved in clinical trials to evaluate the effectiveness of these innovative treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with hidradenitis suppurativa who experience chronic inflammation and pain.
Not a fit: Patients with other skin conditions or those not diagnosed with hidradenitis suppurativa may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly reduce pain and inflammation for patients with hidradenitis suppurativa.
How similar studies have performed: Previous research has shown promise in targeting neuropeptides for treating inflammatory conditions, suggesting potential success for this novel approach.
Where this research is happening
Worcester, United States
- Univ of Massachusetts Med Sch Worcester — Worcester, United States (Active)
Researchers
- Principal investigator: Whitley, Sarah Kern — Univ of Massachusetts Med Sch Worcester
- Study coordinator: Whitley, Sarah Kern
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.