Condition

Axial Spondyloarthritis clinical trials and research

• 17Clinical trials
• 4NIH research projects
• 16Countries

Newest Axial Spondyloarthritis clinical trials

All recruiting trials (17)

• Surface topography and spine damage in radiographic axial spondyloarthritis

  This study tests whether a radiation-free 3D surface topography method can reflect spine damage and sagittal balance in adults with radiographic axial spondyloarthritis.

  Recruiting Ankara Etlik City Hospital · Ankara, Yenimahalle · NCT07855393

• RENEW: a digital program to help people with axial spondyloarthritis manage energy and symptoms

  A web-based, peer-led program called RENEW is tested to see if people with axial spondyloarthritis can easily use it, like it, and benefit from it in managing fatigue and symptoms.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07836374

• ExerciseRx app for people with axial spondyloarthritis

  A mobile app called ExerciseRx is tested to see if it helps people with axial spondyloarthritis exercise more regularly and feel better than usual care.

  Recruiting at 2 sites University of Washington · Seattle, Washington and 1 other locations · NCT07642622

• Carotid ultrasound to guide prevention of heart disease in inflammatory rheumatic diseases

  In people with inflammatory rheumatic diseases like RA, PsA, AxSpA, or SLE who are at modest cardiovascular risk, a carotid ultrasound test is used to see if they should start stronger lipid-lowering therapy to prevent heart problems.

  Recruiting at 7 sites Phase 4 Instituto de Investigación Marqués de Valdecilla · Alicante, Alicante and 16 other locations · NCT07611747

• Bimekizumab by IV infusion versus subcutaneous injection for adults with psoriatic arthritis or axial spondyloarthritis

  This trial tests whether bimekizumab given by intravenous (IV) infusion behaves the same in the body as the usual subcutaneous injection in adults with psoriatic arthritis or axial spondyloarthritis.

  Recruiting at 65 sites Phase 1 UCB Pharma · Peoria, Arizona and 64 other locations · NCT07290036

• Butantan live tetravalent dengue vaccine for people with autoimmune rheumatic diseases

  This study will test whether a single dose of the Butantan live tetravalent dengue vaccine is safe and produces immune responses in clinically stable people aged 12–59 with autoimmune rheumatic diseases compared with matched healthy volunteers.

  Recruiting at 2 sites Phase 4 University of Sao Paulo General Hospital · São Paulo, São Paulo and 1 other locations · NCT07087912

• Assessing Bimekizumab Levels in Breast Milk of Nursing Mothers

  This study tests how much of the medication bimekizumab is found in the breast milk of mothers who have been using it for at least 12 weeks after giving birth to see if it's safe for their babies.

  Recruiting at 14 sites Phase 1 UCB Pharma · Santa Monica, California and 13 other locations · NCT06888193

• Observing the progression of axial spondyloarthritis in Chinese patients

  This study looks at how axial spondyloarthritis changes over time in Chinese adults to better understand the disease and its effects.

  Recruiting China-Japan Friendship Hospital · Beijing · NCT06844643

• Evaluating movement recommendations for patients with axial spondyloarthritis using smartwatches

  This study is testing how using smartwatches to track movement can help people with axial spondyloarthritis find better ways to stay active and manage their symptoms.

  Recruiting University of Bonn · Bonn, North Rhine-Westphalia · NCT06807853

• Investigating the causes and progression of axial spondylitis

  This study is trying to understand how axial spondylitis starts and progresses in newly diagnosed patients to help improve treatments and find better ways to prevent the disease.

  Recruiting at 2 sites Karolinska Institutet · Huddinge, Stockholm County and 1 other locations · NCT06594107

• Fecal microbiota transplantation for treating axial spondyloarthritis

  This study is testing if a treatment using gut bacteria from healthy donors can help people with axial spondyloarthritis who aren't feeling better with their current medications.

  Recruiting Phase 2 University Hospital of North Norway · Tromsø · NCT06451588

• Evaluating the effects of 608 in patients with non-radiographic axial spondyloarthritis

  This study is testing a new treatment called 608 to see if it can help adults with non-radiographic axial spondyloarthritis feel better compared to a placebo.

  Recruiting at 5 sites Phase 2 Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. · Beijing, Beijing Municipality and 5 other locations · NCT06222671

• Evaluating tofacitinib for early active axial spondyloarthritis

  This study is testing if a medication called tofacitinib can help people with early active axial spondyloarthritis who haven't found relief from traditional pain relievers.

  Recruiting Phase 4 Charite University, Berlin, Germany · Berlin · NCT06112665

• High-intensity training for patients with spondyloarthritis

  This study tests if high-intensity interval training can help people with spondyloarthritis feel better and stick to their exercise routines compared to regular training.

  Recruiting Halmstad University · Halmstad, Halland County · NCT05781763

• Observational study on newly diagnosed axial spondyloarthritis in the UK

  This study looks at how being diagnosed later with axial spondyloarthritis affects work and daily life for people in the UK who have just been diagnosed and haven’t started biologic treatment yet.

  Recruiting The Leeds Teaching Hospitals NHS Trust · Leeds · NCT05676775

• Fecal microbiota transplantation for patients with axial spondyloarthritis not responding to standard treatments

  This study is testing if a treatment using fecal microbiota transplantation can help people with axial spondyloarthritis who haven't found relief from standard medications.

  Recruiting Phase 2/3 Assistance Publique - Hôpitaux de Paris · Boulogne-Billancourt · NCT05654753

• Investigating the effects of stopping anti-inflammatory drugs in patients with axial spondyloarthritis

  This study is testing whether stopping anti-inflammatory drugs helps people with axial spondyloarthritis who are in remission stay that way without having flare-ups.

  Recruiting The First Affiliated Hospital of Xiamen University · Xiamen, Fujian · NCT03425812

NIH-funded research (4)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Understanding early triggers of axial spondyloarthritis in people at risk

  This grant aims to understand the early immune changes that lead to axial spondyloarthritis in people who carry a genetic risk, with new peptide tools to distinguish harmful from protective T cells.

  NIH research Washington University · Saint Louis, United States · NIH-11448793

• Pathogenic T cells in axial spondyloarthritis and eye inflammation

  Researchers are studying eye-specific and shared immune mechanisms in axial spondyloarthritis to understand how T cells contribute to eye inflammation and related joint disease, with findings that could guide future treatments.

  NIH research Washington University · Saint Louis, United States · NIH-11370581

• Identifying harmful immune cells in axial spondyloarthritis

  This study is looking at how certain immune cells affect eye inflammation in people with axial spondyloarthritis, which could help us understand how this condition impacts both the eyes and joints.

  NIH research Washington University · Saint Louis, United States · NIH-11292090

• Identifying harmful T cells in a type of arthritis that affects the spine and eyes

  This study is looking at how certain immune cells, called CD8 T cells, behave in people with axial spondyloarthritis, especially when it causes eye inflammation, to help us understand the condition better and find new ways to treat it.

  NIH research Washington University · Saint Louis, United States · NIH-10878955

Related topics

Quick answers

How many Axial Spondyloarthritis clinical trials are recruiting right now?

17, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 16 countries. The most sites are in Germany (4 trials), United States (4 trials), China (3 trials), Spain (2 trials), Sweden (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 3, Phase 2: 2, Phase 1: 2, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →