Understanding pain in hidradenitis suppurativa and improving treatment options
Official title: Pain in Hidradenitis Suppurativa: Phenotypes and Stakeholder Perspectives
Funded at Emory University · NIH-10876491 · Data updated 2026-11-12
This study is looking at how pain affects people with hidradenitis suppurativa and aims to find better ways to help manage that pain and improve their daily lives, with input from both patients and doctors.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | July 8, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $218,543 |
| NIH project number | 5K23AR080245-03 |
| Project ID | NIH-10876491 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with hidradenitis suppurativa who experience chronic pain associated with the condition.
✕Less likely to help
Patients without a diagnosis of hidradenitis suppurativa or those who do not experience pain related to the condition may not benefit from this research.
What this research studies
This research focuses on exploring the mechanisms of pain in patients with hidradenitis suppurativa (HS), a chronic skin condition. The project aims to develop targeted interventions that can alleviate pain and enhance the quality of life for those affected by HS. By employing a combination of prospective studies and stakeholder engagement, the research seeks to gather insights from patients and healthcare providers to inform effective treatment strategies. The principal investigator, Dr. Lauren Orenstein, will work with a team of experts to analyze pain trajectories and evaluate the impact of new interventions.
Why it matters
Potential benefit: If successful, this research could lead to improved pain management strategies and enhanced quality of life for patients with hidradenitis suppurativa.
How similar studies have gone: Previous research has shown promise in understanding pain mechanisms in chronic skin conditions, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Orenstein, Lauren Anne Vigil — Emory University
- Study coordinator: Orenstein, Lauren Anne Vigil
Related research
Other NIH-funded projects on the same topics.
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Anti-CD38 immunotherapy for severe hidradenitis suppurativa
A new treatment using anti-CD38 therapy is being tested for people with severe hidradenitis suppurativa who have not responded to prior therapies.
-
Botulinum toxin blocks nerve signals to immune cells to treat hidradenitis suppurativa
This NIH grant tests a new approach to hidradenitis suppurativa by using botulinum toxin to interrupt nerve signals that may drive skin inflammation in patients.
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Precision therapies for hidradenitis suppurativa using AI
A doctor-researcher team at UC San Francisco is using advanced computer methods to find personalized drug options to treat hidradenitis suppurativa.
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Injectable Hydrogel for HS: a localized therapy to ease painful skin disease
A new baricitinib hydrogel is being developed to deliver pain relief and reduce inflammation directly in hidradenitis suppurativa (HS) lesions, potentially lowering systemic side effects.
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Whole-genome sequencing to understand hidradenitis suppurativa in diverse groups
Researchers will study the genetic factors that contribute to hidradenitis suppurativa, especially in African American, Hispanic/Latino, and White patients, to better understand why some people are more affected.
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Understanding the Genes Behind Hidradenitis Suppurativa in teens and young adults
A study to find genetic factors that contribute to hidradenitis suppurativa (HS), a painful skin condition that often starts in adolescence and affects many Black individuals.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.