Understanding the genetic causes of hidradenitis suppurativa
Determining the Genetic Basis of Hidradenitis Suppurativa
This study is looking at how genes might play a role in hidradenitis suppurativa (HS), a skin condition that can really affect young people's lives, and it involves gathering blood samples from around 2,000 patients to find new genetic clues that could lead to better treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-10981410 on NIH RePORTER |
What this research studies
This research investigates the genetic factors contributing to hidradenitis suppurativa (HS), a chronic skin condition that significantly impacts quality of life, particularly in adolescents and young adults. By analyzing genetic data from a diverse group of 2,000 patients, the study aims to identify new genetic variants associated with HS, building on previous findings from smaller studies. The research will also explore how these genetic factors affect skin cells and inflammation, potentially leading to new treatment options. Patients may be asked to provide blood samples and participate in assessments to help uncover these genetic links.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals aged 12-20 who have been diagnosed with hidradenitis suppurativa.
Not a fit: Patients who do not have hidradenitis suppurativa or are outside the age range of 12-20 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for patients suffering from hidradenitis suppurativa.
How similar studies have performed: Previous studies have successfully identified genetic factors in hidradenitis suppurativa, but this research aims to expand on those findings with a larger and more diverse cohort.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Sayed, Christopher J — Univ of North Carolina Chapel Hill
- Study coordinator: Sayed, Christopher J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.