Understanding the genetic causes of hidradenitis suppurativa in African Americans
Establishing the contributions of monogenic etiologies to hidradenitis suppurativa pathogenesis
This study is looking at the genes that might cause hidradenitis suppurativa, a painful skin condition, especially in African Americans who are affected more than others, to help find better treatments and care for everyone dealing with this issue.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11159205 on NIH RePORTER |
What this research studies
This research investigates the genetic factors contributing to hidradenitis suppurativa (HS), a painful inflammatory skin condition, particularly focusing on the African American population who are disproportionately affected. The study aims to identify specific genetic mutations that may lead to HS, using advanced genetic analysis techniques. By including a larger cohort of African American patients, the research seeks to fill gaps in previous studies that have largely excluded this group. The findings could help in developing targeted treatments and improving management strategies for HS.
Who could benefit from this research
Good fit: Ideal candidates for this research are African American individuals diagnosed with hidradenitis suppurativa.
Not a fit: Patients who do not have hidradenitis suppurativa or those outside the African American demographic may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for hidradenitis suppurativa, particularly for African American patients who currently face significant challenges in managing the condition.
How similar studies have performed: While there have been few genetic studies on hidradenitis suppurativa, the approach of focusing on monogenic causes in underrepresented populations is relatively novel and has shown promise in other inflammatory conditions.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Petukhova, Lynn — New York University School of Medicine
- Study coordinator: Petukhova, Lynn
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.