Condition

Contraception clinical trials and research

• 32Clinical trials
• 75NIH research projects
• 13Countries

Newest Contraception clinical trials

All recruiting trials (32)

• Effectiveness of the Natural Cycles birth control app

  This study will test how well the Natural Cycles app prevents pregnancy over one year in sexually active women aged 18 to 35 with no known infertility.

  Recruiting Natural Cycles · New York, New York · NCT07566793

• Female Reproductive Health in the Canadian Armed Forces: Understanding Issues from Contraception to Pelvic Floor Dysfunction

  This observational study looks at reproductive health among women in the Canadian Armed Forces to see how contraception, pregnancy outcomes, infertility, pelvic floor issues, and related factors affect service members and veterans.

  Recruiting Université de Sherbrooke · Sherbrooke, Quebec · NCT07524764

• Long-acting HIV PrEP and contraception PK study in AGYW

  This study tests how long-acting cabotegravir for PrEP interacts with hormonal contraception in young women.

  Recruiting University of Alabama at Birmingham · Bontleng, Gaborone · NCT07516548

• Vasectomy: Right for Me? — a web-based decision aid

  A web-based decision aid helps men think clearly about vasectomy and other birth control options to see if it fits their goals.

  Recruiting at 2 sites University of Pittsburgh · San Francisco, California and 1 other locations · NCT07451067

• Contraceptive patch designed to stop ovulation

  This trial tests whether a norelgestromin transdermal patch can keep ovulation suppressed for 84 days even when users make intentional application mistakes, in healthy women aged 18–35.

  Recruiting Phase 2 Viatris Inc. · Berlin · NCT07365904

• Helping teens and young adults choose menstrual care and birth control

  This project will try an Encounter Decision Aid to help adolescents and young adults (ages 12–25) make decisions about menstrual management and contraception during outpatient visits.

  Recruiting University Hospital, Geneva · Geneva, Canton of Geneva · NCT07320651

• Mittin intervention to improve contraceptive side effect counseling and follow-up in Addis Ababa

  Aims to see if the Mittin program helps women who use hormonal methods or copper IUDs in Addis Ababa better manage their contraception according to their preferences.

  Recruiting University of California, San Francisco · Addis Ababa · NCT07301281

• Preserving long-acting contraception through counseling

  This trial will test whether structured, culturally sensitive counseling helps women in Islamabad who come for early removal of an IUD or Jadelle implant continue using their long-acting contraception.

  Recruiting at 3 sites Pakistan Institute of Medical Sciences · Islamabad, Islamabad and 2 other locations · NCT07271836

• Long-term testing of an etonogestrel implant placed over the shoulder blade

  This project will test whether placing the etonogestrel contraceptive implant over the shoulder blade gives steady drug levels and acceptable side effects for people assigned female at birth aged 18 to 45.

  Recruiting at 2 sites Phase 2 Yale University · Aurora, Colorado and 1 other locations · NCT07201402

• Family planning messages on sanitary pad packaging

  This project will test whether written and picture messages printed on sanitary pad packaging help postpartum women with babies 9–18 months old learn more about and change their attitudes toward family planning.

  Recruiting Ondokuz Mayıs University · Samsun · NCT07012369

• Buffered versus unbuffered lidocaine paracervical block to reduce pain and measure clinician empathy during IUD placement.

  This will see if buffered or unbuffered lidocaine injections, with or without topical numbing gel, reduce pain and change how much empathy patients feel from clinicians during IUD placement for people aged 18–50 getting an IUD.

  Recruiting University of California, San Diego · La Jolla, California · NCT06960317

• Effects of long-acting contraceptives on women's iron levels and responses to extreme environments

  This study is testing whether long-acting birth control methods can help military women keep their iron levels stable and perform better in extreme environments like heat and cold.

  Recruiting United States Army Research Institute of Environmental Medicine · Natick, Massachusetts · NCT06909695

• Pharmacists using HAPPI software to make birth control easier to get

  This project will test whether the HAPPI software helps pharmacists provide birth control more easily and helps patients access birth control at participating pharmacies.

  Recruiting Empowerx INC · Del Mar, California · NCT06823037

• Levonorgestrel–piroxicam plus placebo vs ulipristal acetate plus placebo for emergency contraception

  This study tests whether a levonorgestrel plus piroxicam combo works better than ulipristal acetate as emergency contraception in women aged 18-45 seeking EC within 120 hours of unprotected sex.

  Recruiting Phase 3 The University of Hong Kong · Hong Kong · NCT06727734

• Connecting patients and clinics to improve postpartum care in the Mississippi Delta

  This project will try community health worker home visits plus a communication and health-literacy program to see if they increase trust and postpartum care engagement among high-risk postpartum mothers in five Mississippi Delta counties.

  Recruiting Jackson State University · Jackson, Mississippi · NCT06481631

• Effects of Drospirenone on Cervical Mucus in Women Undergoing Bariatric Surgery

  This study is testing how a daily pill called Drospirenone affects cervical mucus in Thai women aged 18-45 who are obese and preparing for weight loss surgery.

  Recruiting Chulalongkorn University · Bangkok · NCT06345586

• Effects of bariatric surgery on Drospirenone pill absorption

  This study is testing how bariatric surgery affects how well Drospirenone birth control pills work in obese women.

  Recruiting Phase 1/2 Chulalongkorn University · Bangkok · NCT06345560

• Evaluating how genetics affect the effectiveness of oral contraceptive pills

  This study is testing if a specific genetic variation affects how well oral contraceptive pills work for women aged 18-45.

  Recruiting at 2 sites Phase 4 Yale University · Aurora, Colorado and 1 other locations · NCT06334315

• Information on permanent contraception options for women

  This study is testing if giving women better information about permanent birth control options can help them feel more confident in their choices for avoiding future pregnancies.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06296797

• Safety of estetrol (E4) combined with drospirenone (DRSP) birth control

  This study will test whether a birth control pill combining estetrol (E4) and drospirenone (DRSP) has similar risks of blood clots compared with other commonly used combined oral contraceptives in women of reproductive age.

  Recruiting Center for Epidemiology and Health Research, Germany · Berlin, State of Berlin · NCT06186271

• Evaluating the contraceptive effectiveness of Ovaprene

  This study is testing how well the Ovaprene, a new non-hormonal vaginal ring, works as a birth control option for people assigned female at birth who are looking for contraception.

  Recruiting at 4 sites Daré Bioscience, Inc. · Phoenix, Arizona and 26 other locations · NCT06127199

• Safety study comparing two types of hormonal contraceptives

  This study is testing whether a new hormonal birth control pill is safer than traditional options for women starting these contraceptives.

  Recruiting Center for Epidemiology and Health Research, Germany · Berlin, State of Berlin · NCT06028555

• Permanent birth control using FemBloc

  This study is testing a new method for permanent birth control called FemBloc to see how well it works and is safe for women.

  Recruiting at 12 sites Femasys Inc. · Chandler, Arizona and 11 other locations · NCT05977751

• Improving alcohol and substance use care during the reproductive years

  This project will test whether offering SBIRT (screening, brief intervention, and referral to treatment) in sexual and reproductive health clinics helps adults who screen positive for risky alcohol or drug use reduce substance use and improve mental, reproductive, and overall health.

  Recruiting at 4 sites Emory University · Boston, Massachusetts and 3 other locations · NCT05910580

• Evaluating a new method for inserting a copper intrauterine contraceptive device

  This study is testing a new tool for safely and effectively placing a copper IUD in healthy women aged 18 to 48 to see if it works better than current methods.

  Recruiting University Hospital, Ghent · Ghent · NCT05702281

• Structured contraceptive counseling for pregnant women

  This study tests if providing organized birth control counseling to pregnant women helps them use long-lasting contraception after having their babies.

  Recruiting at 4 sites Dalarna University · Falun and 3 other locations · NCT05550064

• Using Levonorgestrel IUD for Emergency Contraception and Same-Day Start

  This study is testing if the Levonorgestrel IUD can be an effective option for emergency contraception when people start using it on the same day.

  Recruiting at 7 sites Phase 4 University of Utah · San Jose, California and 7 other locations · NCT05444582

• Using etonogestrel implant for emergency contraception

  This study is testing if an etonogestrel implant can work as emergency contraception by preventing ovulation when it's inserted before a certain hormone surge in women with regular menstrual cycles.

  Recruiting Phase 4 University of Colorado, Denver · Aurora, Colorado · NCT05237141

• Investigating the microbiome's effect on pregnancy outcomes in women planning to conceive

  This study is trying to see how the bacteria in the body affect pregnancy outcomes for women who have given birth before and are planning to get pregnant again.

  Recruiting Karolinska Institutet · Stockholm, Huddinge and 1 other locations · NCT05127252

• Long-acting injectable treatment for HIV in young women

  This study is testing a long-acting injectable treatment for HIV in young women to see if it works better than standard pills and helps improve their health and prevent unintended pregnancies.

  Recruiting University of Alabama at Birmingham · Eldoret, Kenya · NCT05044962

• A tool to help women with substance use disorders make reproductive decisions after childbirth

  This study is testing a new tool called MyPath to help women with substance use disorders make better choices about birth control after having a baby.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT04939012

• Investigating how female hormones affect brain blood flow

  This study is testing how female hormones and birth control affect blood flow and activity in the brain for women.

  Recruiting University Ghent · Ghent · NCT03299179

NIH-funded research (newest 40 of 75)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Mobile health support to boost PrEP and contraception use among young women in Zambia

  A mobile health program helps female university students in Zambia learn about and access HIV prevention and contraception.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11570031

• Blocking CFTR in the cervix to prevent conception without hormones

  A non-hormonal approach aims to stop sperm from entering the uterus by making cervical mucus too thick for sperm, potentially offering a new contraception option.

  NIH research Oregon Health & Science University · Portland, United States · NIH-11565149

• Long‑lasting antibody vaginal ring for non‑hormonal birth control

  Testing a vaginal ring that slowly releases an antibody to trap sperm and prevent pregnancy for people seeking non‑hormonal contraception.

  NIH research Mucommune, LLC · Morrisville, UNITED STATES · NIH-11478956

• A woman-controlled, nonhormonal on-demand contraceptive device

  This project is creating a woman-controlled vaginal device that releases a fabric-like polymer which thickens on contact with semen to help prevent pregnancy.

  NIH research St. Louis College of Pharmacy · St. Louis, UNITED STATES · NIH-11478955

• Vaginal ring releasing non-hormonal antibody contraception for month-long use

  A monthly vaginal ring delivers a non-hormonal antibody-based contraceptive, offering a convenient, user-controlled option for women who want to avoid daily dosing or invasive procedures.

  NIH research Mucommune, LLC · Morrisville, UNITED STATES · NIH-11464361

• On-demand non-hormonal vaginal contraception with a fast-dissolving antibody tablet

  A new on-demand vaginal tablet dissolves quickly to release a monoclonal antibody for non-hormonal contraception.

  NIH research Mucommune, LLC · Morrisville, UNITED STATES · NIH-11464360

• Targeted HIPK4 degradation for non-hormonal male contraception

  A study to test a new non-hormonal approach that could safely and reversibly reduce male fertility by targeting a testis-specific protein in developing sperm.

  NIH research Stanford University · Stanford, United States · NIH-11462477

• Reversible male contraception by blocking ALDH1A in men

  A new, non-hormonal pill called KyA84 would temporarily reduce sperm production in men and then allow fertility to return after stopping the pill.

  NIH research University of Washington · Seattle, United States · NIH-11451185

• Precision contraception: how genetics influence hormonal birth control side effects

  Genetic differences may explain why people have different side effects from hormonal birth control, and researchers will use a large national dataset to explore these links.

  NIH research University of Rochester · Rochester, United States · NIH-11441233

• Pregnancy planning and contraception support for people with chronic kidney disease

  A new plan tests a tailored decision-support tool to help people with CKD make informed choices about pregnancy and contraception.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11427362

• Fast-dissolving non-hormonal contraception tablet for on-demand use

  A non-hormonal, fast-acting tablet is being developed to provide discreet, on-demand contraception for women who prefer not to use hormones.

  NIH research Mucommune, LLC · Morrisville, UNITED STATES · NIH-11415806

• Mobile health tool to boost PrEP and contraception use among female university students in Zambia

  A mobile, peer-supported program helps young women in Zambia start and stick with PrEP and modern contraception to prevent HIV and unintended pregnancy.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11385413

• Levonorgestrel IUD for Emergency Contraception and Same-Day Start

  A study is testing whether the LNG 52 mg IUD can be used effectively for emergency contraception and started the same day in eligible people.

  NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11380012

• Life course effects of less access to contraception

  This study looks at how reducing access to contraception affects women's social and economic outcomes over time.

  NIH research University of Colorado · Boulder, UNITED STATES · NIH-11370013

• Testing a new gel for male contraception

  This study is looking at a new gel that combines Nestorone and Testosterone to see if it can safely help men prevent pregnancy by reducing sperm production, giving them another option for contraception besides condoms and vasectomy.

  NIH research Health Decisions, INC. · Morrisville, United States · NIH-11344754

• Evaluating a new injectable contraceptive for women

  This study is testing a new long-lasting birth control shot called levonorgestrel butanoate, especially for women who are overweight and at risk for blood clots, to see if it works well and is safe without the added hormones found in other methods.

  NIH research University of Utah · Salt Lake City, United States · NIH-11337219

• Same-day etonogestrel implant for emergency contraception

  A study to understand how well the etonogestrel implant works as emergency contraception, with and without a little oral LNG, especially for people with higher BMI.

  NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11330400

• Reversible non-hormonal male contraceptive that targets the STK33 protein

  Developing a non-hormonal medicine that temporarily blocks a sperm-related protein (STK33) to provide reversible contraception for adult men.

  NIH research Baylor College of Medicine · Houston, United States · NIH-11321660

• Evaluating a new injectable contraceptive for women

  This study is testing a new long-lasting birth control shot called levonorgestrel butanoate, especially for women who are obese and may be at risk for blood clots, to see if it can be a safer and easier option without the hormones found in many other contraceptives.

  NIH research Oregon Health & Science University · Portland, United States · NIH-11310101

• Two-year implant for birth control and HIV prevention

  This project is developing a small under-the-skin implant to provide two years of contraception and HIV prevention for sexually active women.

  NIH research Methodist Hospital Research Institute · Houston, United States · NIH-11309692

• How patients, partners, and providers shape postpartum contraception and timing of the next pregnancy

  This project explores what influences postpartum contraceptive choices and how long people wait to get pregnant again after giving birth.

  NIH research Northwestern University · Chicago, United States · NIH-11294201

• How family life, pregnancy choices, and parenting shape children's futures

  Researchers are collecting long-term survey information from U.S. families and their children to learn how family relationships, pregnancy decisions, and parenting affect children's lives over generations.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11262293

• Evaluating a new injectable contraceptive for women

  This study is testing a new long-lasting birth control shot called levonorgestrel butanoate, which is made for women, especially those who are overweight and may have a higher risk of blood clots, to see how well it works and how it moves through the body, while offering a safer and easier option than taking a pill eve

  NIH research Health Decisions, INC. · Morrisville, United States · NIH-11251139

• Testing a new gel for male contraception

  This study is looking at a new gel that combines Nestorone and Testosterone to see if it can safely and effectively help men prevent pregnancy when used daily, giving couples more options for contraception.

  NIH research Health Decisions, INC. · Morrisville, United States · NIH-11250937

• Creating a database for sexually transmitted infection preventives

  This study is creating a helpful database to share information about new ways to prevent sexually transmitted infections (STIs) and improve contraceptive methods, so patients can have better options for staying safe and healthy.

  NIH research Public Health Institute · Oakland, United States · NIH-11201811

• Improving postpartum contraception access through pediatric clinics

  This study is looking to make it easier for new moms to get birth control by offering it during their baby's check-ups, so they can take care of their own health while taking care of their little ones.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11193453

• Understanding how reduced access to birth control affects women's lives

  This project looks at how changes in access to birth control can shape women's social and economic well-being over their lifetime.

  NIH research University of Colorado · Boulder, UNITED STATES · NIH-11193279

• Pharmacy delivery of HIV prevention and birth control for young women in Kenya

  This project offers HIV prevention pills (PrEP) and birth control at pharmacies to help adolescent girls and young women in Kenya get and use both services more easily.

  NIH research University of Washington · Seattle, United States · NIH-11191588

• Developing contraceptives that also prevent sexually transmitted infections

  This study is working on new products that combine birth control and protection against sexually transmitted infections, like HIV, to make it easier and more effective for people to stay healthy and safe during sex.

  NIH research · Frederick, United States · NIH-11181779

• Consulting services for improving contraception methods

  This study is all about improving birth control methods by working with experts to make sure new contraceptive drugs are safe and effective, helping to prevent unplanned pregnancies for everyone who needs reliable options.

  NIH research Gardner Pharmacology LLC · Vienna, United States · NIH-11180598

• Consulting on reproductive toxicology for contraceptive development

  This study is all about helping create safer and more effective birth control options for everyone by looking closely at how these methods affect reproductive health.

  NIH research Leading Edge Pharmtox, LLC · Durham, United States · NIH-11180591

• Consulting services for improving contraceptive research

  This study is all about helping to create better birth control methods to prevent unplanned pregnancies, and it's designed for researchers and organizations working on new contraceptive solutions.

  NIH research · Phoenix, United States · NIH-11180587

• Developing a long-lasting injectable system for HIV prevention and contraception

  This study is working on a new gel that can be injected to provide two important medications—one to help prevent HIV and another for birth control—over a long time, and they want to make sure it’s safe and effective while also listening to what potential users think about it.

  NIH research Old Dominion University · Norfolk, United States · NIH-11178981

• Tablet-based peer support to help female university students in Zambia use PrEP and contraception

  A tablet-led peer navigator program to help female university students in Zambia learn about and start using PrEP and modern contraception.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11178682

• Developing safe and effective contraceptives for men and women

  This study is working on new birth control options for both men and women to make sure they are safe and effective, so people can have more choices when it comes to contraception.

  NIH research Sri International · Menlo Park, United States · NIH-11178289

• Evaluating a new injectable contraceptive for women

  This study is testing a new long-lasting birth control shot called levonorgestrel butanoate, especially for women who are overweight and at risk for blood clots, to see if it can be a safer and easier option than traditional methods.

  NIH research Oregon Health & Science University · Portland, United States · NIH-11177579

• Monthly non-hormonal vaginal ring that prevents pregnancy and STIs

  This project is developing a 30-day, non-hormonal intravaginal ring designed to help prevent pregnancy and several sexually transmitted infections, including HIV, for women.

  NIH research Population Council · New York, United States · NIH-11167697

• Developing a new non-hormonal contraceptive for men

  This study is working on a new kind of birth control for men that safely stops sperm production without using hormones, and it's looking for the best compounds to make this possible.

  NIH research Baylor College of Medicine · Houston, United States · NIH-11146641

• Levonorgestrel IUD for Emergency Contraception and Immediate Placement

  This project looks at whether a specific type of IUD can be used for emergency contraception and placed right away, even if you've recently had unprotected sex.

  NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11138701

• Investigating safe contraception options for people with sickle cell disease

  This study is looking at how safe different hormonal birth control methods are for women with sickle cell disease, so they can make informed choices about their options and get better support from their healthcare providers.

  NIH research Emory University · Atlanta, United States · NIH-11126106

Related topics

Quick answers

How many Contraception clinical trials are recruiting right now?

32, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 13 countries. The most sites are in United States (15 trials), Germany (3 trials), Sweden (2 trials), Thailand (2 trials), Belgium (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 3, Phase 2: 2, Phase 3: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →