Condition

Health Literacy clinical trials and research

• 22Clinical trials
• 23NIH research projects
• 2New in 30 days
• 8Countries

Newest Health Literacy clinical trials

All recruiting trials (22)

• My Symptoms Young: a web-based program for teens and young adults with persistent physical symptoms

  A web-based self-help program is being tested to see if it helps 15- to 25-year-olds with persistent physical symptoms in primary care, and whether health literacy affects how well they use it.

  Recruiting Aarhus University Hospital · Aarhus · NCT07912515

• AI-simplified discharge summaries to improve patient understanding

  This randomized pilot tests whether ContextCare can help adults understand their discharge information better than standard discharge words and printouts.

  Recruiting Scarborough Health Network · Scarborough Village, Ontario · NCT07890532

• Digital Health Education to Improve Heart Health Across Different Socioeconomic Groups (e-DUCASS Advance)

  This study tests a 24-month digital health education program to see if it can improve cardiovascular health among people in Córdoba, Spain from varied socioeconomic backgrounds, by delivering weekly online content to families.

  Recruiting Maimónides Biomedical Research Institute of Córdoba · Córdoba · NCT07835386

• AI care summaries to help caregivers understand their child’s hospitalization

  This trial tests whether an AI-generated plain-language summary of inpatient notes helps caregivers of hospitalized children understand their child’s care better.

  Recruiting Children's National Research Institute · Washington D.C., District of Columbia · NCT07831018

• Agentic LLM for Shared Decision Making in Health Care

  This project tests an agentic large language model to help patients participate in health decisions, especially for those with lower health literacy.

  Recruiting Harding Center for Risk Literacy · Neuruppin · NCT07827924

• Senior Center Medication Safety and Empowerment Curriculum

  A program for adults 55+ and their care partners to learn how to safely manage medications and talk with doctors about safer options.

  Recruiting State University of New York at Buffalo · Buffalo, New York · NCT07799610

• Online Sleep Education for College Students' Sleep Health and Executive Functioning

  A psychoeducational sleep program delivered online will be tested to see if it helps college students improve their sleep health knowledge, sleep quality, and better thinking skills.

  Recruiting Northern Arizona University · Phoenix, Arizona · NCT07765849

• eCardiacRehab: a home-based, patient-centered cardiac rehab program

  This trial tests a hybrid home-based cardiac rehabilitation program to see if it reduces cardiovascular deaths and ED visits while improving quality of life for adults with CAD after PCI, compared with usual care.

  Recruiting Haukeland University Hospital · Bergen · NCT07590635

• AI-simplified versus original patient education materials for parents of children with osteogenesis imperfecta

  This tests whether AI-simplified educational materials help parents of children with osteogenesis imperfecta understand the condition better than the original materials.

  Recruiting Hospital for Special Surgery, New York · New York, New York · NCT07505719

• Health literacy education for women using teach-back

  This trial tests whether teach-back health literacy education improves how well women ages 18–65 understand health information compared with standard care.

  Recruiting Istanbul University - Cerrahpasa · Istanbul · NCT07320079

• Cocreating local actions to make healthcare more rational

  This project will test whether working with residents in Elche to cocreate community actions can reduce unnecessary use of mental‑health drugs, cardiovascular medications, and antibiotics and ease pressure on primary care.

  Recruiting at 2 sites Universidad Miguel Hernandez de Elche · Elche, Alicante and 1 other locations · NCT07237971

• Health literacy and self-confidence in managing alcohol-related liver cirrhosis

  This project will measure health literacy and self-confidence in adults with alcohol-related liver cirrhosis to see where extra support or education is needed.

  Recruiting Hannover Medical School · Hanover · NCT07169526

• Mindfulness plus digital health learning to support student health decisions

  This project tests whether brief mindfulness exercises combined with digital e-health lessons help university students aged 18–25 make clearer health decisions and improve e-health, food, and media literacy.

  Recruiting at 2 sites University of Macau · Macao and 1 other locations · NCT07157566

• Caregiver health literacy in children's surgical care

  This tests whether caregivers' health literacy and social circumstances are linked to caregiver anxiety before outpatient pediatric surgeries and to children's pain after surgery.

  Recruiting Nationwide Children's Hospital · Columbus, Ohio · NCT07138482

• Evaluating health literacy in older patients

  This study is trying to see how well older patients understand health information compared to what their doctors think, to improve communication and care for those with multiple health issues.

  Recruiting Hamilton Health Sciences Corporation · Hamilton, Ontario · NCT06971393

• Nurse-led telehealth support for people with gout

  This trial will try nurse-led telehealth support to help adults with gout stay on urate-lowering medicine and keep their uric acid at target after leaving a rheumatology clinic.

  Recruiting at 5 sites University of Aarhus · Aarhus and 4 other locations · NCT06971146

• Using short health education videos to improve transition readiness in adolescents

  This study tests if short health education videos can help teenagers with chronic illnesses feel more prepared for managing their health and attending appointments.

  Recruiting Children's Hospital Los Angeles · Los Angeles, California · NCT06842576

• Program to provide plant-based food prescriptions to address food insecurity

  This program is testing whether giving families in need plant-based food and nutrition education can help them eat healthier and reduce food insecurity.

  Recruiting University of Miami · Miami, Florida · NCT06614920

• Examining health literacy and quality of life in COPD patients

  This study looks at how understanding health information affects the quality of life and daily activities of people with COPD compared to healthy individuals over 40.

  Recruiting Hacettepe University · Ankara, Ankara · NCT06497816

• Connecting patients and clinics to improve postpartum care in the Mississippi Delta

  This project will try community health worker home visits plus a communication and health-literacy program to see if they increase trust and postpartum care engagement among high-risk postpartum mothers in five Mississippi Delta counties.

  Recruiting Jackson State University · Jackson, Mississippi · NCT06481631

• Improving physical activity for people with mobility impairments

  This study is testing whether providing exercise videos and health coaching can help people with mobility challenges become more active and stay motivated over 32 weeks.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT06207084

• Intervention to promote active travel among adolescents

  This study is testing a six-week program in schools to encourage teenagers to walk or bike more by teaching them about health and motivating them to be active.

  Recruiting Nordic Institute for Studies of Innovation, Research and Education · Oslo · NCT06156553

NIH-funded research (23)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Health Literacy Core to Help Patients Understand and Use Health Information

  A health literacy program in Louisiana helps clinicians and researchers make information easier to understand so patients can better manage their health and participate in clinical studies.

  NIH research Lsu Pennington Biomedical Research Ctr · Baton Rouge, United States · NIH-11404396

• Bringing clear health information to PACS patients and providers in rural New England

  A project to create easy-to-understand health information about post-acute COVID syndrome for patients and clinicians in rural northern New England.

  NIH research Dartmouth-Hitchcock Clinic · Lebanon, United States · NIH-11378026

• Health literacy and cognitive function in midlife adults

  A study in adults aged 35–64 will look at how health literacy and self-management relate to early changes in thinking and memory to help prevent Alzheimer’s and related dementias.

  NIH research Northwestern University · Chicago, United States · NIH-11361751

• S3E: A kid-friendly game to learn about indoor environmental health

  A mobile game helps middle-schoolers learn about everyday indoor environmental exposures and how to reduce health risks like asthma and lead poisoning.

  NIH research Dfusion, INC. · Scotts Valley, United States · NIH-11333036

• Helping justice-involved adults find and use health care

  This project compares coach-guided health coaching to self-directed learning to help adults with past justice involvement (ages 18–50) get insurance, a regular provider, and use care when they need it.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11314233

• Endocrine disruptors and men's reproductive health: a home-based program to learn about chemicals and reduce exposures for men trying to conceive

  A home-based program for men to learn about everyday chemical exposures and take steps to reduce them to support healthier semen quality.

  NIH research Million Marker Wellness INC. · El Cerrito, United States · NIH-11313694

• Easier recovery after colorectal surgery for patients with limited health literacy

  This project will adapt standard recovery plans with visual aids, provider coaching, and staff training to help adults with limited health literacy have smoother recoveries after colorectal surgery.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11311845

• Improving mental health support for Latinx adolescents in mixed-status families

  This study is working with Latinx teens from families with different immigration statuses to find better ways to help them deal with feelings of sadness and improve their access to mental health support, while also encouraging open conversations about mental health in their families.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11199652

• A mobile game to teach kids about environmental health risks

  This study is testing a fun mobile game designed for middle school kids to help them learn about the dangers of toxic things in their homes and how to stay healthy in their environment.

  NIH research Dfusion, INC. · Scotts Valley, United States · NIH-11182059

• Improving Health Information for Long COVID Patients in Rural Northern New England

  This effort creates easy-to-understand health information for patients and healthcare providers dealing with Long COVID in rural areas of northern New England.

  NIH research Dartmouth-Hitchcock Clinic · Lebanon, United States · NIH-11180083

• Health Literacy and Brain Health in Middle-Aged Adults

  This project looks at how health knowledge and self-care skills in middle-aged adults might affect their brain health later in life.

  NIH research Northwestern University · Chicago, United States · NIH-11105797

• Improving surgical recovery programs for patients with low health literacy

  This study is looking to make recovery after surgery easier for patients who might struggle to understand health information by using helpful visuals and better communication, so everyone can have a smoother healing process.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11066477

• Improving health literacy to help justice-involved adults access healthcare

  This study is looking to help adults involved in the justice system in San Diego better understand and access healthcare by providing them with support or self-study tools, so they can get the medical help they need.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11063972

• Health literacy and thinking skills in older adults and caregivers

  This long-term project follows older adults and their caregivers to track how thinking skills and health literacy change and affect managing health.

  NIH research Northwestern University · Chicago, United States · NIH-10979423

• Improving reproductive health access for Afghan and Syrian newcomers through digital resources

  This study is all about helping Afghan and Syrian refugees in Sacramento understand reproductive health better by providing easy-to-access information in their languages and making sure it fits their cultural needs, so they can get the care they deserve.

  NIH research University of California-Irvine · Irvine, United States · NIH-10891555

• Improving mental health understanding for young Black adults

  This study is all about helping Black and African American young adults, aged 18-35, better understand and access mental health resources, especially after the tough times brought on by COVID-19, by creating a supportive program that fits their community needs.

  NIH research Rutgers, the State Univ of N.j. · Piscataway, United States · NIH-10890863

• A tool to improve health literacy for Native American and Alaska Native students

  This study is creating a helpful app called HealthyU-Native to support Native American and Alaska Native high school students in learning about health, so they can better understand health information and make healthier choices.

  NIH research Oregon Res Behavioral Intervention Strat · Springfield, UNITED STATES · NIH-10821128

• Improving the transition from hospital to home for children with complex medical needs

  This study is all about helping families with children who have complex medical needs by improving communication between doctors and parents, so they can better understand how to care for their child when they leave the hospital and avoid any complications at home.

  NIH research New York University School of Medicine · New York, United States · NIH-10816428

• Improving health information access for rural patients with Long COVID

  This study is working to make health information easier to understand for patients and healthcare providers dealing with long-term COVID symptoms in rural northern New England, so they can get the support they need.

  NIH research Dartmouth-Hitchcock Clinic · Lebanon, United States · NIH-10791541

• Improving colorectal cancer screening decisions for older adults with low health literacy

  This study is all about helping older adults who may find it hard to understand health information make better choices about colorectal cancer screening by creating an easy-to-read pamphlet that addresses their needs and preferences.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-10782505

• Improving understanding of how the environment affects health

  This study is all about helping people understand how the environment affects their health, using fun activities and materials created by local businesses and schools, so everyone can make better choices for their well-being.

  NIH research Nzumbe Epigenetics · Portland, United States · NIH-10757960

• A program to help reduce sugary drink consumption among adults in rural Appalachia

  This study is all about helping adults in rural Appalachian areas drink less sugary beverages by using a friendly online program that offers tips and support for making healthier choices.

  NIH research University of Virginia · Charlottesville, United States · NIH-10756106

• A technology tool to improve health literacy for Latinx students and their families

  This study is creating a fun and interactive online program called HealthyU-Latinx to help Latinx teens and their families learn about health and how to make smart healthcare choices.

  NIH research Oregon Res Behavioral Intervention Strat · Springfield, UNITED STATES · NIH-10699830

Related topics

Quick answers

How many Health Literacy clinical trials are recruiting right now?

22, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in United States (9 trials), Germany (2 trials), Turkey (Türkiye) (2 trials), Norway (2 trials), Canada (2 trials). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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