Testing a new gel for male contraception

COORDINATION, MONITORING, FOLLOW-UP, EVALUATION, AND COMPLETION OF A CLINICAL TRIAL OF NESTORONE TESTOSTERONE GEL FOR MALE CONTRACEPTION

NIH-funded research Health Decisions, INC. · NIH-11344754

This study is looking at a new gel that combines Nestorone and Testosterone to see if it can safely help men prevent pregnancy by reducing sperm production, giving them another option for contraception besides condoms and vasectomy.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionHealth Decisions, INC. NIH-funded
Lab location1 site (Morrisville, United States)
Project IDNIH-11344754 on NIH RePORTER

What this research studies

This research investigates the safety and effectiveness of a combination gel containing Nestorone and Testosterone for male contraception. Participants will apply the gel daily to assess its ability to suppress sperm production and provide a reversible contraceptive option. The study is part of a larger effort to expand contraceptive choices for men beyond current methods like condoms and vasectomy. The trial will involve multiple sites to ensure comprehensive data collection and evaluation.

Who could benefit from this research

Good fit: Ideal candidates for participation are healthy men who are seeking reversible contraception and are willing to engage in a clinical trial.

Not a fit: Patients who are not interested in male contraception or those with contraindications to hormonal treatments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide men with a new, effective, and reversible contraceptive option.

How similar studies have performed: Previous research has shown promise in developing hormonal contraceptives for men, indicating potential for success with this novel approach.

Where this research is happening

Morrisville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.