Testing a new gel for male contraception
Official title: COORDINATION, MONITORING, FOLLOW-UP, EVALUATION, AND COMPLETION OF A CLINICAL TRIAL OF NESTORONE TESTOSTERONE GEL FOR MALE CONTRACEPTION
Funded at Health Decisions, INC. · NIH-11344754 · Data updated 2026-11-12
This study is looking at a new gel that combines Nestorone and Testosterone to see if it can safely help men prevent pregnancy by reducing sperm production, giving them another option for contraception besides condoms and vasectomy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Health Decisions, INC. NIH-funded |
| Lab location | 1 site (Morrisville, United States) |
| Project start | May 1, 2025 |
| Project end | October 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $700,175 |
| NIH project number | 75N94019D00004-0-759402500001-1 |
| Project ID | NIH-11344754 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation are healthy men who are seeking reversible contraception and are willing to engage in a clinical trial.
✕Less likely to help
Patients who are not interested in male contraception or those with contraindications to hormonal treatments may not benefit from this research.
What this research studies
This research investigates the safety and effectiveness of a combination gel containing Nestorone and Testosterone for male contraception. Participants will apply the gel daily to assess its ability to suppress sperm production and provide a reversible contraceptive option. The study is part of a larger effort to expand contraceptive choices for men beyond current methods like condoms and vasectomy. The trial will involve multiple sites to ensure comprehensive data collection and evaluation.
Why it matters
Potential benefit: If successful, this research could provide men with a new, effective, and reversible contraceptive option.
How similar studies have gone: Previous research has shown promise in developing hormonal contraceptives for men, indicating potential for success with this novel approach.
Where this research is happening
-
Health Decisions, INC.
Morrisville, United States Active
Researchers
- Principal investigator: Dart, Clint — Health Decisions, INC.
- Study coordinator: Dart, Clint
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.