Clinical trial Recruiting at 1 site Interventional Ages 18 to 45 Women only

Effects of Drospirenone on Cervical Mucus in Women Undergoing Bariatric Surgery

Official title: Drospirenone Only Pills and Cervical Mucus Changes in Obese Thai Women: A Pre- and Post-Bariatric Surgery Study

Run by Chulalongkorn University · NCT06345586 · Data updated 2026-11-12

This study is testing how a daily pill called Drospirenone affects cervical mucus in Thai women aged 18-45 who are obese and preparing for weight loss surgery.

More Contraception trials

Quick facts

Study typeInterventional
Ages18 Years to 45 Years
SexWomen only
Enrollment16 (estimated)
SponsorChulalongkorn University
Academic / other
Locations1 site (Bangkok)
StatusRecruiting
StartedApril 18, 2024
Main results expectedJuly 2026
Study endsJuly 2026
Registry record updatedMarch 18, 2026
Trial IDNCT06345586 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are Thai women aged 18-45 who are obese, scheduled for bariatric surgery, and require contraception.

Probably not a fit

Patients who are pregnant, breastfeeding, or have contraindications to Drospirenone will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates how Drospirenone-only pills affect cervical mucus changes in Thai women aged 18-45 who are obese and scheduled for bariatric surgery. Participants will take 4 mg of Drospirenone daily, and their cervical mucus will be evaluated using a modified Insler score on days 4-7 of the treatment. The study aims to compare the cervical mucus changes before and after the bariatric surgery to understand the impact of the medication in this specific population.

Why it matters

Potential benefit: If successful, this study could provide insights into effective contraceptive options for obese women undergoing bariatric surgery.

How similar studies have gone: While there may be studies on hormonal contraceptives, this specific focus on Drospirenone and cervical mucus changes in the context of bariatric surgery is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Thai women aged 18-45 years who are obese and had an appointment for Bariatric surgery at Chulalongkorn Hospital
* Need contraception
* Able to use non-hormonal contraception during the study
* Giving consent

Exclusion Criteria:

* Pregnancy or history of giving birth within 3 months
* Breastfeeding within the 6 months
* History of using DMPA within 12 months
* History of using other types of hormonal birth control pills within 4 weeks
* History of bilateral oophorectomy or hysterectomy
* Suspected ovarian tumor or pathological ovarian cyst
* Regular cigarette smoking
* Contraindications to Drospirenone

Where it's running

  • Chulalongkorn University
    Bangkok, Thailand
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.