Effects of Drospirenone on Cervical Mucus in Women Undergoing Bariatric Surgery
Drospirenone Only Pills and Cervical Mucus Changes in Obese Thai Women: A Pre- and Post-Bariatric Surgery Study
This study is testing how a daily pill called Drospirenone affects cervical mucus in Thai women aged 18-45 who are obese and preparing for weight loss surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 16 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | Female |
| Sponsor | Chulalongkorn University Academic / other |
| Locations | 1 site (Bangkok) |
| Trial ID | NCT06345586 on ClinicalTrials.gov |
What this trial studies
This study investigates how Drospirenone-only pills affect cervical mucus changes in Thai women aged 18-45 who are obese and scheduled for bariatric surgery. Participants will take 4 mg of Drospirenone daily, and their cervical mucus will be evaluated using a modified Insler score on days 4-7 of the treatment. The study aims to compare the cervical mucus changes before and after the bariatric surgery to understand the impact of the medication in this specific population.
Who should consider this trial
Good fit: Ideal candidates are Thai women aged 18-45 who are obese, scheduled for bariatric surgery, and require contraception.
Not a fit: Patients who are pregnant, breastfeeding, or have contraindications to Drospirenone will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into effective contraceptive options for obese women undergoing bariatric surgery.
How similar studies have performed: While there may be studies on hormonal contraceptives, this specific focus on Drospirenone and cervical mucus changes in the context of bariatric surgery is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Thai women aged 18-45 years who are obese and had an appointment for Bariatric surgery at Chulalongkorn Hospital * Need contraception * Able to use non-hormonal contraception during the study * Giving consent Exclusion Criteria: * Pregnancy or history of giving birth within 3 months * Breastfeeding within the 6 months * History of using DMPA within 12 months * History of using other types of hormonal birth control pills within 4 weeks * History of bilateral oophorectomy or hysterectomy * Suspected ovarian tumor or pathological ovarian cyst * Regular cigarette smoking * Contraindications to Drospirenone
Where this trial is running
Bangkok
- Chulalongkorn University — Bangkok, Thailand (Recruiting)
Study contacts
- Principal investigator: Punyawee Utaipatanacheep — Chulalongkorn University
- Study coordinator: Punyawee Utaipatanacheep
- Email: punyawee@docchula.com
- Phone: +668-7515-4003
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.