Effects of Drospirenone on Cervical Mucus in Women Undergoing Bariatric Surgery
Official title: Drospirenone Only Pills and Cervical Mucus Changes in Obese Thai Women: A Pre- and Post-Bariatric Surgery Study
Run by Chulalongkorn University · NCT06345586 · Data updated 2026-11-12
This study is testing how a daily pill called Drospirenone affects cervical mucus in Thai women aged 18-45 who are obese and preparing for weight loss surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 45 Years |
| Sex | Women only |
| Enrollment | 16 (estimated) |
| Sponsor | Chulalongkorn University Academic / other |
| Locations | 1 site (Bangkok) |
| Status | Recruiting |
| Started | April 18, 2024 |
| Main results expected | July 2026 |
| Study ends | July 2026 |
| Registry record updated | March 18, 2026 |
| Trial ID | NCT06345586 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are Thai women aged 18-45 who are obese, scheduled for bariatric surgery, and require contraception.
✕Probably not a fit
Patients who are pregnant, breastfeeding, or have contraindications to Drospirenone will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates how Drospirenone-only pills affect cervical mucus changes in Thai women aged 18-45 who are obese and scheduled for bariatric surgery. Participants will take 4 mg of Drospirenone daily, and their cervical mucus will be evaluated using a modified Insler score on days 4-7 of the treatment. The study aims to compare the cervical mucus changes before and after the bariatric surgery to understand the impact of the medication in this specific population.
Why it matters
Potential benefit: If successful, this study could provide insights into effective contraceptive options for obese women undergoing bariatric surgery.
How similar studies have gone: While there may be studies on hormonal contraceptives, this specific focus on Drospirenone and cervical mucus changes in the context of bariatric surgery is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Thai women aged 18-45 years who are obese and had an appointment for Bariatric surgery at Chulalongkorn Hospital * Need contraception * Able to use non-hormonal contraception during the study * Giving consent Exclusion Criteria: * Pregnancy or history of giving birth within 3 months * Breastfeeding within the 6 months * History of using DMPA within 12 months * History of using other types of hormonal birth control pills within 4 weeks * History of bilateral oophorectomy or hysterectomy * Suspected ovarian tumor or pathological ovarian cyst * Regular cigarette smoking * Contraindications to Drospirenone
Where it's running
-
Chulalongkorn University
Bangkok, Thailand Recruiting
Study contacts
- Principal investigator: Punyawee Utaipatanacheep — Chulalongkorn University
- Study coordinator: Punyawee Utaipatanacheep
- Email: punyawee@docchula.com
- Phone: +668-7515-4003
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Effectiveness of the Natural Cycles birth control app
This study will test how well the Natural Cycles app prevents pregnancy over one year in sexually active women aged 18 to 35 with no known infertility.
-
Female Reproductive Health in the Canadian Armed Forces: Understanding Issues from Contraception to Pelvic Floor Dysfunction
This observational study looks at reproductive health among women in the Canadian Armed Forces to see how contraception, pregnancy outcomes, infertility, pelvic floor issues, and related factors affect service members and veterans.
-
Long-acting HIV PrEP and contraception PK study in AGYW
This study tests how long-acting cabotegravir for PrEP interacts with hormonal contraception in young women.
-
Vasectomy: Right for Me? — a web-based decision aid
A web-based decision aid helps men think clearly about vasectomy and other birth control options to see if it fits their goals.
-
Contraceptive patch designed to stop ovulation
This trial tests whether a norelgestromin transdermal patch can keep ovulation suppressed for 84 days even when users make intentional application mistakes, in healthy women aged 18–35.
-
Helping teens and young adults choose menstrual care and birth control
This project will try an Encounter Decision Aid to help adolescents and young adults (ages 12–25) make decisions about menstrual management and contraception during outpatient visits.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.