On-demand non-hormonal vaginal contraception with a fast-dissolving antibody tablet
Official title: Clinical development of MM011, an instantly dissolving vaginal tablet releasing HCMA for on-demand non-hormonal contraception
Funded at Mucommune, LLC · NIH-11464360 · Data updated 2026-11-12
A new on-demand vaginal tablet dissolves quickly to release a monoclonal antibody for non-hormonal contraception.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mucommune, LLC NIH-funded |
| Lab location | 1 site (Morrisville, UNITED STATES) |
| Project start | September 7, 2026 |
| Project end | August 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $1,441,607 |
| NIH project number | 1P50HD123737-01 |
| Project ID | NIH-11464360 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals seeking non-hormonal, on-demand contraception who want a discreet delivery method.
✕Less likely to help
People seeking long-acting or daily contraception, or those with contraindications to vaginal products, may not benefit.
What this research studies
This project aims to create MM011, a fast-dissolving vaginal tablet that instantly releases a monoclonal antibody to provide contraception when needed. The tablet is designed to dissolve in vaginal secretions in under 2 minutes, delivering active HMCA antibodies. If successful, it could offer a discrete, non-hormonal option for people who have infrequent sex or prefer on-demand protection.
Why it matters
Potential benefit: If successful, this could provide a discreet, non-hormonal contraception option that works quickly and avoids daily or hormonal dosing.
How similar studies have gone: Earlier non-hormonal, on-demand options exist but face limitations; this platform aims to improve speed and acceptability.
Where this research is happening
-
Mucommune, LLC
Morrisville, United States Active
Researchers
- Principal investigator: Moench, Thomas Ray — Mucommune, LLC
- Study coordinator: Moench, Thomas Ray
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.