Permanent birth control using FemBloc
Official title: FINALE: Prospective Multi-Center Trial for FemBloc INtratubal Occlusion for TranscervicAL PErmanent Birth Control
Run by Femasys Inc. · NCT05977751 · Data updated 2026-11-12
This study is testing a new method for permanent birth control called FemBloc to see how well it works and is safe for women.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 21 Years to 50 Years |
| Sex | Women only |
| Enrollment | 573 (estimated) |
| Sponsor | Femasys Inc. Industry-sponsored |
| Locations | 12 sites (Chandler, Arizona and 11 other locations) |
| Status | Recruiting |
| Started | October 31, 2023 |
| Main results expected | December 2029 |
| Study ends | June 2031 |
| Registry record updated | October 23, 2026 |
| Trial ID | NCT05977751 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are women aged 21 to 50 who are sexually active and desire permanent contraception.
✕Probably not a fit
Patients who are uncertain about their desire to end fertility or have a history of gynecologic malignancy may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This trial evaluates the effectiveness of FemBloc, a method for permanent birth control, through a prospective, multi-center approach. Participants will undergo the FemBloc procedure followed by an ultrasound confirmation test to ensure the procedure's success. The study is unblinded and single-arm, meaning all participants will receive the same intervention without a control group. It aims to gather data from various international sites to assess the procedure's safety and efficacy.
Why it matters
Potential benefit: If successful, this could provide a reliable and effective method for women seeking permanent birth control.
How similar studies have gone: Other studies on permanent birth control methods have shown success, indicating that this approach is promising and not entirely novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Female, 21 - 50 years of age desiring permanent birth control. * Sexually active with male partner. * Regular menstrual cycle for last 3 months or on hormonal contraceptives. Exclusion Criteria: * Uncertainty about the desire to end fertility. * Known or suspected pregnancy. * Prior tubal surgery, including sterilization attempt. * Presence, suspicion, or previous history of gynecologic malignancy. * Scheduled to undergo concomitant intrauterine procedures (i.e. endometrial ablation) at the time of either FemBloc Treatment or prior to final confirmation test. * Abnormal uterine bleeding requiring evaluation or treatment.
Where it's running
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New Horizons Clinical Trials
Chandler, Arizona, United States Recruiting -
Stanford University
Palo Alto, California, United States Recruiting -
University of California Davis
Sacramento, California, United States Recruiting -
Midtown OB GYN North
Columbus, Georgia, United States Recruiting -
Atrium Health Navicent
Macon, Georgia, United States Recruiting -
Rosemark WomenCare Specialists
Idaho Falls, Idaho, United States Recruiting
Show 6 more locations
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Maimonides Medical Center
Brooklyn, New York, United States Recruiting -
Columbia University Medical Center/NYPH
New York, New York, United States Recruiting -
Seven Hills Women's Health Centers
Cincinnati, Ohio, United States Recruiting -
Chattanooga Medical Research LLC
Chattanooga, Tennessee, United States Recruiting -
Baylor Scott & White Research Institute
Temple, Texas, United States Recruiting -
University of Utah
Salt Lake City, Utah, United States Recruiting
Study contacts
- Study coordinator: Study Director
- Email: StudySupport@Femasys.com
- Phone: 770-500-3910 Ext. 146
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.