Evaluating a new injectable contraceptive for women

CCTN-PHARMACOKINETIC / PHARMACODYNAMIC EVALUATION OF LEVONORGESTREL BUTANOATE FOR FEMALE CONTRACEPTION - UTAH

NIH-funded research University of Utah · NIH-11337219

This study is testing a new long-lasting birth control shot called levonorgestrel butanoate, especially for women who are overweight and at risk for blood clots, to see if it works well and is safe without the added hormones found in other methods.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Utah NIH-funded
Lab location1 site (Salt Lake City, United States)
Project IDNIH-11337219 on NIH RePORTER

What this research studies

This research investigates a new long-acting injectable contraceptive called levonorgestrel butanoate, designed specifically for women, particularly those who are obese and at risk for venous thromboembolism (VTE). The study aims to provide an estrogen-free alternative to traditional contraceptive methods, which often require strict adherence and may pose additional health risks. By focusing on a population that has limited options, the research seeks to assess the efficacy and safety of this new formulation in a clinical trial setting. Participants will be monitored for adherence and contraceptive effectiveness over the course of the study.

Who could benefit from this research

Good fit: Ideal candidates for this research are women of childbearing age who are obese and seeking effective contraception without the risks associated with estrogen.

Not a fit: Patients who are not obese or those who do not require contraception may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a safer and more convenient contraceptive option for women, especially those who are obese.

How similar studies have performed: Previous research has shown success with other long-acting contraceptive methods, but this specific formulation is novel and aims to address a unique patient population.

Where this research is happening

Salt Lake City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.