Evaluating a new injectable contraceptive for women

CCTN-PHARMACOKINETIC / PHARMACODYNAMIC EVALUATION OF LEVONORGESTREL BUTANOATE FOR FEMALE CONTRACEPTION - OREGON

NIH-funded research Oregon Health & Science University · NIH-11310101

This study is testing a new long-lasting birth control shot called levonorgestrel butanoate, especially for women who are obese and may be at risk for blood clots, to see if it can be a safer and easier option without the hormones found in many other contraceptives.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionOregon Health & Science University NIH-funded
Lab location1 site (Portland, United States)
Project IDNIH-11310101 on NIH RePORTER

What this research studies

This research investigates a new long-acting injectable contraceptive called levonorgestrel butanoate, designed specifically for women, particularly those who are obese and at risk for venous thromboembolism (VTE). The study aims to provide an estrogen-free alternative to traditional contraceptive methods, which often require strict adherence and may pose additional health risks. By conducting a clinical trial, the researchers will assess the efficacy and safety of this new formulation, making it easier for women to manage their contraceptive needs without the associated risks of estrogen. The trial will gather data on how well this new contraceptive works and its potential benefits for women in the target demographic.

Who could benefit from this research

Good fit: Ideal candidates for this research are women of childbearing age, especially those who are obese and seeking estrogen-free contraceptive options.

Not a fit: Patients who are not seeking contraception or who do not fall within the childbearing age range may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a safer and more convenient contraceptive option for women, particularly those who are obese.

How similar studies have performed: Previous research has shown success with other long-acting contraceptive methods, suggesting potential for this novel approach.

Where this research is happening

Portland, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.