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Anesthesia, Local clinical trials and research

• 11Clinical trials
• 5Countries

Newest Anesthesia, Local clinical trials

All recruiting trials (11)

• Different doses of corticosteroid in local knee injection for total knee replacement

  This will test whether adding different doses of Diprospan to the local pain injection given during primary unilateral total knee replacement reduces postoperative pain and improves early recovery.

  Recruiting First Affiliated Hospital of Fujian Medical University · Fuzhou, Fujian · NCT07337772

• Buffered versus unbuffered lidocaine paracervical block to reduce pain and measure clinician empathy during IUD placement.

  This will see if buffered or unbuffered lidocaine injections, with or without topical numbing gel, reduce pain and change how much empathy patients feel from clinicians during IUD placement for people aged 18–50 getting an IUD.

  Recruiting University of California, San Diego · La Jolla, California · NCT06960317

• Comparing how long local anesthetics last in dermatologic surgery

  This study is testing whether using different amounts of a local anesthetic during skin surgery affects how long the numbness lasts, especially in areas with lots of blood vessels.

  Recruiting Phase 4 Weill Medical College of Cornell University · New York, New York · NCT06694714

• Comparing pain relief methods after lumbar fusion surgery

  This study tests whether a new way of giving local anesthesia during lumbar fusion surgery can help patients feel less pain and use fewer opioids compared to the traditional method.

  Recruiting University of Massachusetts, Worcester · Worcester, Massachusetts · NCT06528288

• Effect of PENG Block on Pain After Hip Surgery

  This study is testing if a new pain relief method called the PENG block can help people feel less pain after hip surgery compared to a placebo.

  Recruiting Phase 4 Copenhagen University Hospital, Rigshospitalet · Copenhagen · NCT06406010

• Using silver diamine fluoride to improve anesthesia in children with hypomineralized molars

  This study is testing if applying silver diamine fluoride before dental work can help make local anesthesia work better and reduce pain for children with sensitive molars.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT05964387

• Identifying risks for cardiovascular and neurocognitive diseases using biomarkers

  This study is trying to see if measuring certain markers in the blood can help identify people over 45 who are at risk for heart and brain diseases before they have surgery.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT05951764

• Impact of eating before WALANT procedures on patient anxiety and outcomes

  This study tests if eating a light meal before certain surgeries can help reduce anxiety and improve satisfaction for patients.

  Recruiting University of California, Irvine · Orange, California · NCT05819801

• ESP nerve block versus wound infiltration for pain after laminectomy

  This trial will try whether an erector spinae plane (ESP) block or wound infiltration gives better pain relief and reduces opioid use for adults having a one- or two-level laminectomy.

  Recruiting University of Padova · Padova, Veneto · NCT05271331

• Using erector spinae plane block catheters with intrathecal morphine for pain relief after liver surgery

  This study is testing if using special catheters for pain relief along with morphine can help people recovering from liver surgery feel less pain and recover faster compared to standard pain management.

  Recruiting Phase 4 University of California, San Diego · San Diego, California · NCT04849455

• Using electrical stimulation to confirm epidural catheter placement in laboring women

  This study tests if using electrical stimulation can help confirm the correct placement of epidural catheters for women in labor who want pain relief.

  Recruiting Stanford University · Palo Alto, California · NCT04109365

Related topics

Quick answers

How many Anesthesia, Local clinical trials are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in United States (7 trials), Italy (1 trial), China (1 trial), France (1 trial), Denmark (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 3. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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