Testing a new gel for male contraception
Official title: COORDINATION, MONITORING, FOLLOW-UP, AND EVALUATION OF A CLINICAL TRIAL OF NESTORONE TESTOSTERONE GEL FOR MALE CONTRACEPTION
Funded at Health Decisions, INC. · NIH-11250937 · Data updated 2026-11-12
This study is looking at a new gel that combines Nestorone and Testosterone to see if it can safely and effectively help men prevent pregnancy when used daily, giving couples more options for contraception.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Health Decisions, INC. NIH-funded |
| Lab location | 1 site (Morrisville, United States) |
| Project start | January 1, 2023 |
| Project end | August 26, 2025 |
| Funding year | 2025 |
| Award (this year) | $701,569 |
| NIH project number | 75N94019D00004-P00007-759402300001-1 |
| Project ID | NIH-11250937 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are healthy men in committed relationships who are seeking reversible contraception.
✕Less likely to help
Patients who are not in a stable relationship or those who are not seeking male contraceptive options may not benefit from this research.
What this research studies
This research investigates the use of a combination gel containing Nestorone and Testosterone for male contraception. The study aims to evaluate the safety and effectiveness of this gel when applied daily by male partners in couples. Participants will be monitored closely to assess sperm production suppression and overall contraceptive efficacy. The research is part of a broader initiative to expand contraceptive options available to men, addressing the current limitations in male contraceptive methods.
Why it matters
Potential benefit: If successful, this research could provide men with a safe and effective hormonal contraceptive option.
How similar studies have gone: Previous studies have shown promise in hormonal male contraceptives, but this specific approach is relatively novel and untested in a large-scale clinical trial.
Where this research is happening
-
Health Decisions, INC.
Morrisville, United States Active
Researchers
- Principal investigator: Dart, Clint — Health Decisions, INC.
- Study coordinator: Dart, Clint
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.