Testing a new gel for male contraception

COORDINATION, MONITORING, FOLLOW-UP, AND EVALUATION OF A CLINICAL TRIAL OF NESTORONE TESTOSTERONE GEL FOR MALE CONTRACEPTION

NIH-funded research Health Decisions, INC. · NIH-11250937

This study is looking at a new gel that combines Nestorone and Testosterone to see if it can safely and effectively help men prevent pregnancy when used daily, giving couples more options for contraception.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionHealth Decisions, INC. NIH-funded
Lab location1 site (Morrisville, United States)
Project IDNIH-11250937 on NIH RePORTER

What this research studies

This research investigates the use of a combination gel containing Nestorone and Testosterone for male contraception. The study aims to evaluate the safety and effectiveness of this gel when applied daily by male partners in couples. Participants will be monitored closely to assess sperm production suppression and overall contraceptive efficacy. The research is part of a broader initiative to expand contraceptive options available to men, addressing the current limitations in male contraceptive methods.

Who could benefit from this research

Good fit: Ideal candidates for this research are healthy men in committed relationships who are seeking reversible contraception.

Not a fit: Patients who are not in a stable relationship or those who are not seeking male contraceptive options may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide men with a safe and effective hormonal contraceptive option.

How similar studies have performed: Previous studies have shown promise in hormonal male contraceptives, but this specific approach is relatively novel and untested in a large-scale clinical trial.

Where this research is happening

Morrisville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.