Investigating how female hormones affect brain blood flow
The Effects of the Female Sex Hormones and Hormonal Contraception on Cerebral Perfusion
This study is testing how female hormones and birth control affect blood flow and activity in the brain for women.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 62 (estimated) |
| Ages | 18 Years to 25 Years |
| Sex | Female |
| Sponsor | University Ghent Academic / other |
| Locations | 1 site (Ghent) |
| Trial ID | NCT03299179 on ClinicalTrials.gov |
What this trial studies
This observational study aims to measure variations in cerebral perfusion and other brain parameters influenced by female sex hormones and hormonal contraception. Participants will undergo MRI scans, physiological monitoring, and blood sample collection to assess brain activity, connectivity, and diffusion. The study focuses on understanding how menstrual cycles and contraceptive use impact brain function and blood flow. By analyzing these factors, researchers hope to gain insights into the physiological effects of female hormones on the brain.
Who should consider this trial
Good fit: Ideal candidates are Bachelor or Master students who have not used hormonal contraception for at least three months.
Not a fit: Patients with MRI contraindications, chronic diseases, or those who are pregnant or breastfeeding may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of how hormonal changes affect brain health and function in women.
How similar studies have performed: While studies on hormonal effects on brain function exist, this specific approach focusing on cerebral perfusion variations is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Bachelor or Master student * Minimum of 3 months not using contraception of using Deso20 Exclusion Criteria: * No informed consent * MRI-contraindications * Claustrophobia * Pregnancy or breastfeeding * Chronic diseases and chronic medication use * Smoker * Drug use * Abuse of alcohol and caffeine
Where this trial is running
Ghent
- Ghent University Hospital — Ghent, Belgium (Recruiting)
Study contacts
- Principal investigator: Eric Achten, MD, PhD — University Hospital, Ghent
- Study coordinator: Patricia Clement, Msc
- Email: patricia.clement@ugent.be
- Phone: 9 332 1330
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.