Effects of bariatric surgery on Drospirenone pill absorption

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates how bariatric surgery impacts the absorption of Drospirenone-only pills in obese women. Participants will take the pills daily, and their pharmacokinetics will be measured before and after the surgery. The goal is to understand any changes in how the body processes the medication due to surgical weight loss. This could provide important insights into contraceptive effectiveness in this population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Thai women aged 18-45 years who are obese and had an appointment for Bariatric surgery at Chulalongkorn Hospital
* Need contraception
* Able to use non-hormonal contraception during the study
* Giving consent

Exclusion Criteria:

* Pregnancy or history of giving birth within 3 months
* Breastfeeding within the 6 months
* History of using DMPA within 12 months
* History of using other types of hormonal birth control pills within 4 weeks
* History of bilateral oophorectomy or hysterectomy
* Suspected ovarian tumor or pathological ovarian cyst
* Regular cigarette smoking
* Contraindications to Drospirenone

Where it's running

• Chulalongkorn University
  Bangkok, Thailand Recruiting

Study contacts

• Principal investigator: Punyawee Utaipatanacheep — Chulalongkorn University
• Study coordinator: Punyawee Utaipatanacheep
• Email: punyawee@docchula.com
• Phone: +668-7515-4003

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.