Evaluating heart health risks after breast cancer radiotherapy
Acute and Long-term Cardiovascular Toxicity After Modern Radiotherapy for Breast Cancer - a Prospective Longitudinal Study
This study is trying to see if newer radiotherapy techniques for breast cancer can lower the risk of heart problems compared to traditional methods in patients over 15 years.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1600 (estimated) |
| Ages | 30 Years to 70 Years |
| Sex | Female |
| Sponsor | St. Olavs Hospital Academic / other |
| Drugs / interventions | trastuzumab, radiation |
| Locations | 2 sites (Ålesund and 1 other locations) |
| Trial ID | NCT02541435 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the incidence and prevalence of cardiovascular diseases in breast cancer patients who have undergone different radiotherapy techniques. It will compare outcomes between patients treated with conventional radiotherapy and those treated with newer laser-assisted breath-controlled radiotherapy. The study will follow these two cohorts over a period of 15 years to determine if advancements in radiotherapy reduce the risk of cardiovascular complications. The research will utilize various imaging techniques to monitor heart health over time.
Who should consider this trial
Good fit: Ideal candidates for this study are women diagnosed with breast cancer who have an expected life expectancy of over 10 years.
Not a fit: Patients who are unwilling to participate in the study will not benefit from its findings.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment protocols that minimize cardiovascular risks for breast cancer survivors.
How similar studies have performed: While there have been studies on cardiovascular risks associated with breast cancer treatments, this specific comparison of newer radiotherapy techniques is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * diagnosis of breast cancer * expected life-expectancy above 10 years Exclusion Criteria: * Not willing to participate
Where this trial is running
Ålesund and 1 other locations
- Ålesund Hospital — Ålesund, Norway (Recruiting)
- St Olavs University Hospital — Trondheim, Norway (Recruiting)
Study contacts
- Study coordinator: torgeir wethal, md phd
- Email: torgeir.wethal@stolav.no
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.