Clinical trial Recruiting at 2 sites Observational Ages 30 to 70 Women only

Evaluating heart health risks after breast cancer radiotherapy

Official title: Acute and Long-term Cardiovascular Toxicity After Modern Radiotherapy for Breast Cancer - a Prospective Longitudinal Study

Run by St. Olavs Hospital · NCT02541435 · Data updated 2026-11-12

This study is trying to see if newer radiotherapy techniques for breast cancer can lower the risk of heart problems compared to traditional methods in patients over 15 years.

More Cardiovascular Diseases trials

Quick facts

Study typeObservational
Ages30 Years to 70 Years
SexWomen only
Enrollment1600 (estimated)
SponsorSt. Olavs Hospital
Academic / other
Drugs / interventionstrastuzumab, radiation
Locations2 sites (Ålesund and 1 other locations)
StatusRecruiting
StartedNovember 2016
Main results expectedDecember 2029
Study endsDecember 2036
Registry record updatedJune 4, 2026
Trial IDNCT02541435 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are women diagnosed with breast cancer who have an expected life expectancy of over 10 years.

Probably not a fit

Patients who are unwilling to participate in the study will not benefit from its findings.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the incidence and prevalence of cardiovascular diseases in breast cancer patients who have undergone different radiotherapy techniques. It will compare outcomes between patients treated with conventional radiotherapy and those treated with newer laser-assisted breath-controlled radiotherapy. The study will follow these two cohorts over a period of 15 years to determine if advancements in radiotherapy reduce the risk of cardiovascular complications. The research will utilize various imaging techniques to monitor heart health over time.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment protocols that minimize cardiovascular risks for breast cancer survivors.

How similar studies have gone: While there have been studies on cardiovascular risks associated with breast cancer treatments, this specific comparison of newer radiotherapy techniques is novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* diagnosis of breast cancer
* expected life-expectancy above 10 years

Exclusion Criteria:

* Not willing to participate

Where it's running

  • Ålesund Hospital
    Ålesund, Norway
    Recruiting
  • St Olavs University Hospital
    Trondheim, Norway
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.