Preoperative exercise to prevent lymphedema in breast cancer patients
Official title: Effect of Preoperative Exercise on the Prevention of Secondary Lymphedema in Breast Cancer Patients
Run by Asan Medical Center · NCT06421285 · Data updated 2026-11-12
This study is testing if a special exercise program before surgery can help breast cancer patients avoid lymphedema after chemotherapy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 80 Years |
| Sex | Women only |
| Enrollment | 60 (estimated) |
| Sponsor | Asan Medical Center Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Seoul, Seoul Special City) |
| Status | Recruiting |
| Started | January 10, 2025 |
| Main results expected | October 30, 2025 |
| Study ends | December 31, 2025 |
| Registry record updated | June 29, 2025 |
| Trial ID | NCT06421285 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are breast cancer patients aged 20 to 80 who are starting neoadjuvant chemotherapy before surgery.
✕Probably not a fit
Patients with medical contraindications to exercise or those with pain or musculoskeletal conditions limiting active exercise may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of preoperative exercise in preventing lymphedema in patients diagnosed with breast cancer who are scheduled for neoadjuvant chemotherapy. Participants will be randomly assigned to either an intervention group, which will engage in a tailored exercise program including aerobic, strength, and flexibility exercises, or a control group that will receive minimal flexibility training. The primary outcome will measure the incidence and severity of postoperative lymphedema, while secondary outcomes will assess upper extremity dysfunctions and quality of life. The intervention will last for at least three months during the chemotherapy period before surgery.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence of lymphedema and improve the quality of life for breast cancer patients post-surgery.
How similar studies have gone: Other studies have shown promising results with exercise interventions in similar patient populations, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 20 or older and younger than 80 who were first diagnosed with breast cancer * Patients scheduled for surgery and starting neoadjuvant chemotherapy before surgery Exclusion Criteria: * Patients with medical contraindications to exercise intervention or pain or musculoskeletal conditions that may limit active exercise intervention
Where it's running
-
Seoul Asan Medical Center
Seoul, Seoul Special City, South Korea Recruiting
Study contacts
- Principal investigator: Jaeyong Jeon — Asan Medical Center
- Study coordinator: Jaeyong Jeon
- Email: jyjeon71@gmail.com
- Phone: +82-2-3010-3791
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.