Detecting circulating tumor cells in patients with luminal A breast cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients with luminal A breast cancer, a common type among early-stage and postmenopausal women. It aims to evaluate the effectiveness of detecting circulating tumor cells (CTCs) as a cost-effective method for monitoring prognosis and treatment efficacy, compared to traditional imaging techniques. The study will involve PET-CT examinations and peripheral blood detection to assess the number and protein expression of CTCs. By following patients post-surgery, the study seeks to provide insights into the potential of CTCs as molecular markers for breast cancer management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* estrogen receptor (≥ 10%), progesterone receptor (≥ 10%) and epidermal growth factor receptor 2 negative;
* proliferation index Ki-67 \< 20%;
* no lymph node metastasis;
* systemic therapy (chemotherapy, radiotherapy and endocrine therapy) in accordance with the National Comprehensive Cancer Network guidelines;
* provision of informed consent of patients and their families.

Exclusion Criteria:

* Bilateral breast cancer;
* inflammatory breast cancer;
* pregnancy or lactation;
* history of other cancers or chest radiotherapy.

Where it's running

• Shengjing Hospital of China Medical University
  Shenyang, Liaoning, China Recruiting
• Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute
  Shenyang, Liaoning, China Recruiting

Study contacts

• Principal investigator: Jianyi Li, MD — Shengjing Hospital
• Study coordinator: Jianyi Li
• Email: sjbreast@yeah.net
• Phone: +8618940257177

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.