Using cryotherapy to prevent eyebrow and eyelash loss in breast cancer patients undergoing chemotherapy
Official title: Effect of Cryotherapy in the Prevention of Alopecia in Eyebrows and Eyelashes in Breast Cancer Patients Treated With Anthracyclines and Taxanes
Run by University of Salamanca · NCT06955702 · Data updated 2026-11-12
This study is testing whether cryotherapy can help breast cancer patients keep their eyebrows and eyelashes while they undergo chemotherapy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 120 (estimated) |
| Sponsor | University of Salamanca Academic / other |
| Drugs / interventions | chemotherapy, immunotherapy |
| Locations | 2 sites (Santander, Cantabria and 1 other locations) |
| Status | Recruiting |
| Started | November 15, 2023 |
| Main results expected | July 31, 2025 |
| Study ends | August 31, 2026 |
| Registry record updated | May 22, 2025 |
| Trial ID | NCT06955702 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are women over 18 years old, newly diagnosed with breast cancer, and scheduled to receive specific chemotherapy treatments.
✕Probably not a fit
Patients with recurrent breast cancer or those who have previously undergone chemotherapy or hormone therapy may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of targeted cryotherapy in preventing madarosis, or loss of eyebrows and eyelashes, in breast cancer patients receiving anthracycline- and taxane-based chemotherapy. Patients will undergo cryotherapy sessions before and after chemotherapy infusions, with hair retention measured at multiple timepoints using photogrammetric analysis. Additionally, the study aims to assess the impact of this intervention on patients' quality of life through validated questionnaires. The research will be conducted at two hospitals in Spain, with a total of 120 participants expected to enroll.
Why it matters
Potential benefit: If successful, this approach could significantly improve the quality of life for breast cancer patients by preserving their eyebrows and eyelashes during chemotherapy.
How similar studies have gone: While scalp cryotherapy has shown success in preventing hair loss, the specific application of cryotherapy for preventing madarosis is less established and represents a novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Female participants aged ≥18 years * Newly diagnosed breast cancer (any stage) * Scheduled to receive anthracycline- and/or taxane-based chemotherapy as first-line systemic treatment * No prior history of antineoplastic treatment * Willing and able to provide written informed consent Exclusion Criteria: * Patients with recurrent disease who have received prior hormone therapy, chemotherapy, and/or immunotherapy * Presence of alopecia prior to the initiation of cancer treatment * History of cerebral radiotherapy
Where it's running
-
Hospital Marqués de Valdecilla
Santander, Cantabria, Spain Recruiting -
Hospital Universitario de Salamanca
Salamanca, Salamanca, Spain Recruiting
Study contacts
- Principal investigator: Marta González Fernández-Conde — Universidad Salamanca
- Study coordinator: Marta González Fernández-Conde, PhD Nursing
- Email: martagfc@usal.es
- Phone: 661544179
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.