Tracking body composition changes after breast cancer treatment
Official title: Long-term Evaluation of the Body Composition and the Impact of Resistance and Relaxation Exercise on Muscle Mass and Quality of Life in Patients With Breast Cancer
Run by Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation · NCT07472803 · Data updated 2026-11-12
This project will see how muscle mass and fat distribution change over two years in adults treated for stage I–III breast cancer.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 100 (estimated) |
| Sponsor | Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (New Taipei City, Xindian Dist) |
| Status | Recruiting |
| Started | May 19, 2025 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | March 16, 2026 |
| Trial ID | NCT07472803 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults older than 18 with newly diagnosed stage I–III non‑metastatic breast cancer within 12 months who are scheduled for surgery and adjuvant therapy, who will remain locally available for follow‑up and are not planning pregnancy, are ideal candidates.
✕Probably not a fit
Patients with metastatic (stage IV) disease, those with incompatible implantable devices or joint replacements that prevent accurate body composition measurement, or those planning to relocate or become pregnant during the study are unlikely to benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a longitudinal observational cohort that will follow patients from shortly after diagnosis through two years of post-treatment recovery, with serial measurements of skeletal muscle mass index (SMI), fat distribution, and metabolic markers. Participants are adults with stage I–III non‑metastatic breast cancer scheduled for surgery and adjuvant therapy. No experimental treatments are given; the study collects imaging and body composition data at multiple time points to map trends in muscle loss, fat redistribution, and related metabolic changes. The design aims to characterize natural recovery patterns to inform survivorship care.
Why it matters
Potential benefit: If successful, the data could help identify patients at risk for sarcopenia or adverse fat redistribution and guide personalized rehabilitation and follow‑up care.
How similar studies have gone: Previous observational cohorts have documented post‑treatment muscle loss and changes in fat distribution in cancer survivors, so the general approach is established though local longitudinal data remain valuable.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * \>18 years of age * Diagnosed with stage I-III non-metastatic breast cancer within 12 months of diagnosis * Scheduled for surgery, chemotherapy, with or without radiotherapy or targeted therapy. Exclusion Criteria: * Women diagnosed with metastatic (stage IV) breast cancer * Women planning to move away from the area or be away for more than 6 months during the study period * Women planning to become pregnant during the study period * Implantable devices (e.g., pacemaker, nerve stimulator) or surgical implants (e.g., total hip or knee replacements)
Where it's running
-
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
New Taipei City, Xindian Dist, Taiwan Recruiting
Study contacts
- Study coordinator: Valeria Chiu, Attending Physician
- Email: haydenbell28@gmail.com
- Phone: +886266289779
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.