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Clinical trials and research at Uppsala University

• 56Clinical trials
• 17Countries

Newest trials

All recruiting trials (56)

• Early wear of a Vitamin E-infused liner in a dual-mobility hip replacement

  This study tests whether a Vitamin E-infused liner in a dual-mobility hip implant wears as little as a conventional liner over two years in adults needing hip replacement.

  Recruiting Phase 4 Uppsala University · Uppsala, Uppsala County · NCT07863557

• Group-based Emotional Awareness and Expression Therapy to Support Recovery After Acquired Brain Injury

  A group therapy program based on EAET is tested to see if it helps adults 18-65 with acquired brain injury improve emotional well-being and daily functioning.

  Recruiting Uppsala University · Uppsala · NCT07852936

• Direct lateral vs posterolateral approach for cemented total hip replacement

  This study tests whether the surgical approach affects muscle healing and early recovery after cemented total hip replacement in people with hip OA.

  Recruiting Uppsala University · Gävle · NCT07851597

• Remote Balance in Everyday Life for young MI patients with distress

  This study tests a remote 6-session program (rBEL) to help adults under 55 who had a heart attack and feel distressed see if the program and study procedures are feasible.

  Recruiting Uppsala University · Uppsala · NCT07706816

• Home-based cardiovascular health screening for people turning 50, 55, 60, 65, 70 or 75 in Uppsala

  This trial tests whether giving people a home blood pressure monitor, a dried blood spot kit, and a questionnaire can find more cardiovascular risk factors than usual care.

  Recruiting Uppsala University · Uppsala · NCT07614659

• Thumb base arthritis: joint replacement vs trapeziectomy

  This trial tests whether a total thumb joint replacement (TOUCH prosthesis) works as well as trapeziectomy for people with basal thumb arthritis.

  Recruiting Uppsala University · Uppsala · NCT07569549

• HiHat: Rituximab Followed by Cladribine in Relapsing-Remitting MS

  This trial tests whether giving rituximab and then cladribine in sequence is safe and doable for people with relapsing-remitting MS.

  Recruiting at 3 sites Phase 2 Uppsala University · Falun and 3 other locations · NCT07517185

• Robotic-assisted pedicle screw placement for spine surgery

  This project will test whether using robotic systems to place pedicle screws in spine surgery improves screw accuracy, lowers reoperation rates, and changes the learning curve for patients of all ages who need pedicle-screw fixation.

  Recruiting at 9 sites Uppsala University · Gothenburg and 8 other locations · NCT07461636

• Blood biomarkers for treatment-related brain injury in children with brain tumors

  This project will test whether blood plasma biomarkers can show treatment-related brain injury in children with primary brain tumors by comparing those who receive radiotherapy, those who do not, and healthy children of the same age and sex.

  Recruiting Uppsala University · Uppsala · NCT07381959

• Open TAP block versus wound catheter for children having abdominal surgery

  This will test whether an open TAP block or a continuous wound catheter gives better postoperative pain relief for children aged 1–15 undergoing open abdominal surgery.

  Recruiting Uppsala University · Uppsala · NCT07352683

• Postoperative acute kidney injury in children after major non-cardiac surgery

  This international observational study will test whether urinary biomarkers can help predict postoperative acute kidney injury in hospitalized children (0–16 years) undergoing major non-cardiac surgery.

  Recruiting at 6 sites Uppsala University · Perth, Western Australia and 15 other locations · NCT07351149

• Near‑total debulking surgery versus non‑surgical management for metastatic pancreatic neuroendocrine tumours

  This study will test whether removing most of the tumour (near‑total debulking surgery) helps adults with stage 4 non‑functional pancreatic neuroendocrine tumours live longer or feel better compared with not doing debulking.

  Recruiting at 3 sites Uppsala University · Gothenburg and 3 other locations · NCT07273409

• Online ACT vs Recuperation and Vocational Support for Clinical Burnout

  Three online treatments are tested to see which helps adults with clinical burnout return to work and feel better compared with each other.

  Recruiting Uppsala University · Uppsala, Uppsala County · NCT07272421

• Oral pivmecillinam versus usual antibiotic step-down for E. coli febrile urinary tract infection

  This trial will try oral pivmecillinam as follow-up treatment for adults with E. coli febrile urinary tract infection who have improved after 2–4 days of IV antibiotics.

  Recruiting at 3 sites Phase 4 Uppsala University · Haukeland and 12 other locations · NCT07236944

• How women experience a resilience-based program after partner violence

  See how a resilience-based program fits and helps women who have experienced intimate partner violence.

  Recruiting Uppsala University · Uppsala, Uppsala County · NCT07235722

• Swedish version of a short shame questionnaire (External and Internal Shame Scale)

  This project will test a Swedish translation of an 8-item shame questionnaire in adults who can read Swedish.

  Recruiting Uppsala University · Uppsala · NCT07206966

• Improved Oral Health for Head and Neck Cancer Survivors

  Aiming to see if a structured oral care program helps head and neck cancer survivors keep their mouths healthier and feel better after treatment.

  Recruiting Uppsala University · Uppsala · NCT07173270

• How a Western versus a fiber-rich diet affects sleep and daily body rhythms

  It will test whether eating a Western-style unhealthy diet versus a healthier, fiber-rich diet changes sleep quality and daily heart, glucose, and hormone rhythms in healthy young adults.

  Recruiting Uppsala University · Uppsala · NCT07138313

• How endocrine tumors develop resistance to alkylating chemotherapy

  This study will test whether patients with endocrine tumors who receive alkylating chemotherapy develop high tumor mutation rates and whether blood tests and imaging can detect those changes.

  Recruiting Uppsala University · Uppsala · NCT07121998

• Negative pressure dressings after emergency midline laparotomy

  This trial will test whether using negative pressure wound therapy on adults having emergency midline laparotomy lowers wound complications compared with standard dressings.

  Recruiting at 5 sites Uppsala University · Eskilstuna and 5 other locations · NCT07003906

• Non-surgical versus surgical care for displaced lateral clavicle fractures

  This trial will test whether non-surgical care (sling and physiotherapy) works as well as surgery for adults aged 18–65 with displaced lateral clavicle fractures.

  Recruiting at 8 sites Uppsala University · Odense and 10 other locations · NCT06981065

• PDGFRβ PET imaging to detect cardiac fibrosis after heart attack or in HFpEF

  This project will test whether a PET tracer that binds PDGFRβ can spot fibrogenic cells in the hearts of people after a STEMI, in patients with HFpEF, and in healthy volunteers.

  Recruiting Uppsala University · Uppsala · NCT06956560

• Home-based screening for undiagnosed heart failure

  This study tests a new home screening method to see if it can help find undiagnosed heart failure in high-risk patients better than regular care.

  Recruiting Uppsala University · Uppsala · NCT06940544

• Improving metabolic health in sleep apnea patients using CPAP treatment

  This study is testing how using CPAP treatment for sleep apnea can help improve blood sugar control in people with diabetes or prediabetes.

  Recruiting Uppsala University · Uppsala, Uppsala County · NCT06848647

• Baby swimming to help new mothers with depression and attachment issues

  This study tests whether baby swimming can help new moms with depression feel better and build a stronger bond with their babies.

  Recruiting Uppsala University · Uppsala · NCT06807801

• Comparing fusion surgery and non-surgical treatment for low back pain

  This study tests whether fusion surgery or a structured non-surgical treatment works better for people with chronic low back pain from degenerative disc disease.

  Recruiting at 4 sites Uppsala University · Gothenburg and 3 other locations · NCT06709391

• Healthy Nordic diet's effects on heart disease

  This study is testing if following a Healthy Nordic diet can help people with coronary heart disease improve their heart health over 18 months.

  Recruiting Uppsala University · Uppsala · NCT06701968

• Investigating how night shift work affects women's health during their menstrual cycle

  This study tests how working night shifts and lack of sleep affects the health of young women during different stages of their menstrual cycle.

  Recruiting Uppsala University · Uppsala, Uppsala County · NCT06683248

• Internet therapy for prolonged grief disorder

  This study is testing if online therapy can help adults with prolonged grief feel better after losing a loved one.

  Recruiting at 2 sites Uppsala University · Uppsala and 1 other locations · NCT06667674

• Understanding nutrition care in cancer treatment

  This study looks at how dietitians can help cancer patients improve their nutrition and overall well-being during treatment by using personalized plans and tracking their food intake and muscle health.

  Recruiting Uppsala University · Uppsala · NCT06531174

• Measuring extracellular water to define volume status in sepsis

  This project will test whether measuring extracellular water helps describe volume status in adults with sepsis and unstable blood pressure.

  Recruiting Uppsala University · Uppsala, Uppsa · NCT06512129

• Online emotion-regulation cognitive behavioral therapy for premenstrual dysphoric disorder

  This test tries an 8-week therapist-guided online cognitive behavioral program focused on emotion regulation to reduce symptoms in women aged 18–45 with PMDD.

  Recruiting Uppsala University · Uppsala, Uppsala County · NCT06496139

• Short versus long immunotherapy after radical surgery for high-risk malignant melanoma

  This will test whether six months of immunotherapy works as well as the standard 12 months for adults who have had surgery for high-risk melanoma.

  Recruiting at 26 sites Phase 3 Uppsala University · Helsinki and 25 other locations · NCT06488482

• Comparing triple therapy to double therapy for high volume metastatic prostate cancer

  This study is testing whether a combination of three treatments is better than two for men with advanced prostate cancer to see which option helps them live longer and feel better.

  Recruiting Uppsala University · Uppsala, Region Uppsala and 1 other locations · NCT06446401

• Metacognitive group therapy for autistic teens with anxiety and depression

  This project will try group metacognitive therapy to see if it helps 15–18-year-olds with autism who have anxiety and/or depression.

  Recruiting Uppsala University · Haninge, Stockholm County · NCT06441786

• Evaluating outcomes of breast-conserving surgery for cancer patients

  This study is testing how well a specific type of breast surgery works for cancer patients and how it affects their quality of life and recovery, while also considering their personal choices in treatment.

  Recruiting at 3 sites Uppsala University · Sydney and 2 other locations · NCT06401304

• Validation of a sleep questionnaire for children in Sweden

  This study is testing a sleep questionnaire to see if it can accurately identify sleep problems in children aged 18 months to 15 years who have breathing issues while sleeping.

  Recruiting Uppsala University · Uppsala · NCT06367400

• Exercise intervention for lung regeneration in COPD patients

  This study is testing if a special exercise program can help improve lung function and overall health in people with COPD by promoting lung healing.

  Recruiting at 2 sites Uppsala University · Lund and 1 other locations · NCT06335992

• Behavioral Activation for Depression in Older Adults in Primary Care

  A telephone-based behavioral activation program is being tested to see if it can reduce depressive symptoms in people 65 and older who live in Sweden and visit primary care.

  Recruiting Uppsala University · Uppsala, Uppland and 1 other locations · NCT06284889

• Comparing bortezomib-bendamustine-melphalan to melphalan for treating multiple myeloma

  This study is testing if a new treatment combining bortezomib, bendamustine, and melphalan can help people with relapsed multiple myeloma do better than the standard high-dose melphalan treatment.

  Recruiting Uppsala University · Uppsala · NCT06245629

• Comparing internal fixation and hip arthroplasty for hip fractures in elderly patients

  This study is testing whether surgery to fix a hip fracture or replacing the hip altogether helps older patients feel less pain and move better after their injury.

  Recruiting Uppsala University · Uppsala · NCT06152198

• Improving sleep to reduce pain after joint surgery

  This study is testing if helping people with insomnia sleep better before knee or hip surgery can reduce their pain after the operation.

  Recruiting Uppsala University · Uppsala, Uppland · NCT06145516

• Translating and validating a questionnaire for opioid misuse in Swedish pain patients

  This study is testing a new Swedish questionnaire to see if it can help identify opioid misuse among pain patients who are using opioids for treatment.

  Recruiting Uppsala University · Uppsala, Uppland · NCT06084520

• CAR20(NAP)-T therapy for B-cell lymphoma

  This study is testing a new treatment that uses modified immune cells to help people with B-cell lymphoma fight their cancer better, especially for those who haven't had success with other treatments.

  Recruiting at 2 sites Phase 1/2 Uppsala University · Stockholm and 1 other locations · NCT06002659

• Observational study on early stage psychosis and its mechanisms

  This study looks at people with early stage psychosis and those at risk for it, using brain scans and tests over five years to see how their brains work and what might cause their symptoms.

  Recruiting Uppsala University · Uppsala · NCT05763966

• Predicting long-term outcomes for patients with aortic stenosis after valve intervention

  This study is trying to see how well patients with severe aortic stenosis do after they have heart valve surgery or a procedure, by following their health over a few years.

  Recruiting Uppsala University · Uppsala · NCT05629104

• Comparing two treatments for benign prostatic hyperplasia

  This study is testing whether a new procedure called Prostate Artery Embolization works better than the traditional surgery for treating enlarged prostate symptoms in men.

  Recruiting Uppsala University · Helsingborg, Region Skånes and 3 other locations · NCT05531240

• Evaluating night splinting after needle fasciotomy for Dupuytren's contracture

  This study is testing if wearing a night splint after a needle procedure for Dupuytren's contracture can help prevent the condition from coming back compared to just physical therapy alone.

  Recruiting at 3 sites Uppsala University · Falun, Dalarna County and 2 other locations · NCT05300893

• Treatment for colorectal cancer with hyperthermic chemotherapy

  This study is testing if a new combination of chemotherapy drugs given after surgery can help people with colorectal cancer that has spread to the lining of the abdomen feel better and live longer compared to standard treatment.

  Recruiting at 5 sites Phase 3 Uppsala University · Ahmedabad and 4 other locations · NCT04861558

• Using nanoparticles for delayed lymph node biopsy in breast cancer patients

  This study is testing if using special nanoparticles can help breast cancer patients avoid unnecessary surgery by identifying important lymph nodes only when needed.

  Recruiting at 9 sites Phase 3 Uppsala University · Houston, Texas and 8 other locations · NCT04722692

• Understanding how beta-lactam antibiotics work in patients with infective endocarditis

  This study is trying to see how beta-lactam antibiotics work in patients with infective endocarditis and how different factors like age and weight might affect their effectiveness.

  Recruiting at 2 sites Uppsala University · Gothenburg and 3 other locations · NCT04647331

• Comparing hip screws and hip replacement for elderly patients with certain hip fractures

  This study tests if hip replacement surgery can help older patients with certain hip fractures avoid needing more surgeries compared to traditional hip screws.

  Recruiting at 23 sites Uppsala University · Uppsala, Uppsala County and 24 other locations · NCT03966716

• Investigating inflammatory factors in acute kidney injury among ICU patients

  This study is trying to see if certain inflammation markers can help us understand why some ICU patients develop acute kidney injury, especially those with sepsis or who have had major surgery.

  Recruiting Uppsala University · Uppsala, Uppsala County · NCT03720860

• Assessing the role of imaging in follow-up after surgery for high-risk melanoma

  This study is testing if adding imaging tests like CT or PET scans during follow-up after surgery can help people with high-risk melanoma live longer compared to just regular doctor visits.

  Recruiting at 15 sites Uppsala University · Borås and 19 other locations · NCT03116412

• Testing spironolactone for heart failure with preserved ejection fraction

  This study is testing if adding spironolactone to standard care can help people with heart failure and preserved ejection fraction live longer and avoid hospital visits.

  Recruiting at 29 sites Phase 3 Uppsala University · Alexander City, Alabama and 77 other locations · NCT02901184

• Proton radiotherapy for adult brain tumors

  This study is testing whether proton beam therapy is a safe and effective treatment for adults with brain tumors to see how it affects their survival and quality of life.

  Recruiting at 6 sites Phase 2 Uppsala University · Gothenburg and 5 other locations · NCT02797366

Quick answers

How many clinical trials run by Uppsala University are recruiting right now?

56, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 17 countries. The most sites are in Sweden (56 trials), Norway (3 trials), United States (2 trials), Finland (2 trials), Australia (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 4, Phase 4: 2, Phase 2: 2, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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