Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Online ACT vs Recuperation and Vocational Support for Clinical Burnout

Official title: A Three-Arm Randomized Controlled Trial Comparing Online ACT, Recuperation, and ACT Plus Vocational Support for Clinical Burnout

Run by Uppsala University · NCT07272421 · Data updated 2026-11-12

Three online treatments are tested to see which helps adults with clinical burnout return to work and feel better compared with each other.

More Burnout trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment400 (estimated)
SponsorUppsala University
Academic / other
Locations1 site (Uppsala, Uppsala County)
StatusRecruiting
StartedDecember 1, 2025
Main results expectedMay 31, 2028
Study endsMay 31, 2028
Registry record updatedNovember 10, 2026
Trial IDNCT07272421 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18+ with clinical burnout, currently on 25% or more sick leave, able to read Swedish, and with daily internet access.

Probably not a fit

Individuals with severe psychiatric conditions, substance abuse, or active suicidal ideation may not benefit and are excluded.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized trial in Sweden compares three 10-week online programs for adults with clinical burnout who are on sick leave or having work difficulties. The arms are online Acceptance and Commitment Therapy (ACT), a recuperation-focused online treatment, and a program with vocational support aimed at returning to work. Participants are adults 18 or older, with internet access, and on at least 25% sick leave. The study is led by Uppsala University and is delivered via an online platform from the Institute of Psychology in Uppsala.

Why it matters

Potential benefit: If successful, the program could offer scalable online options that help people with burnout return to work and improve daily functioning.

How similar studies have gone: Similar online psychological approaches for burnout are being explored, with evidence varying by program type; this trial tests three distinct online formats.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18 years or older
* Self-reported or clinically verified symptoms consistent with clinical burnout (e.g., pronounced fatigue, cognitive difficulties, and reduced stress tolerance following prolonged psychosocial stress)
* Currently on ≥25% sick leave and experiencing significant functional impairment in work or daily life due to these symptoms
* Stable occupation or engagement (employment or studies)
* Ability to read and write Swedish
* Daily access to the internet

Exclusion Criteria:

* Sick leave \> 2 years for the current episode
* Severe acute psychiatric conditions, including: severe depression, bipolar disorder, untreated PTSD, schizophrenia, or other psychotic disorders
* Current substance abuse
* Active suicidal ideation (as assessed during clinical evaluation)

Where it's running

  • Instution of Psychology (online)
    Uppsala, Uppsala County, Sweden
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.