Clinical trial Recruiting at 1 site Interventional Ages 18 to 35 Women only

Investigating how night shift work affects women's health during their menstrual cycle

Official title: The Effects of Night Shift Work on Health Across the Menstrual Cycle: a Pilot Study

Run by Uppsala University · NCT06683248 · Data updated 2026-11-12

This study tests how working night shifts and lack of sleep affects the health of young women during different stages of their menstrual cycle.

Quick facts

Study typeInterventional
Ages18 Years to 35 Years
SexWomen only
Enrollment60 (estimated)
SponsorUppsala University
Academic / other
Locations1 site (Uppsala, Uppsala County)
StatusRecruiting
StartedApril 25, 2022
Main results expectedDecember 31, 2024
Study endsDecember 31, 2025
Registry record updatedNovember 14, 2024
Trial IDNCT06683248 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are healthy young women with regular menstrual cycles who do not use hormonal contraceptives.

Probably not a fit

Patients with chronic diseases, those who use hormonal contraceptives, or individuals with regular nicotine or excessive alcohol consumption may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study examines the impact of sleep deprivation on the health of women across different phases of their menstrual cycle. It focuses on healthy young women who do not use hormonal contraceptives, aiming to fill the knowledge gap regarding how hormonal fluctuations influence responses to sleep deprivation. Participants will experience both sleep and wake conditions to assess the effects on brain health and metabolism. The study is particularly interested in the role of estrogen, a hormone that may protect against neurodegenerative conditions.

Why it matters

Potential benefit: If successful, this study could lead to improved health strategies for women working night shifts, potentially reducing risks associated with sleep deprivation.

How similar studies have gone: While studies have explored sleep deprivation and its effects on health, this specific focus on women’s hormonal cycles is relatively novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

\- Healthy

Exclusion Criteria:

* Use of hormonal contraceptives
* Chronic disease
* Regular use of nicotine
* Use of medication
* Consumes excessive amounts of alcohol or coffee

Where it's running

  • Uppsala University
    Uppsala, Uppsala County, Sweden
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.