Internet therapy for prolonged grief disorder
Efficacy and Mechanisms of Change of Online Cognitive Behavioural Therapy for Prolonged Grief Disorder After Loss: a Three-armed Randomised Control Trial
This study is testing if online therapy can help adults with prolonged grief feel better after losing a loved one.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 270 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Uppsala University Academic / other |
| Locations | 2 sites (Uppsala and 1 other locations) |
| Trial ID | NCT06667674 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the effectiveness of internet-delivered Cognitive Behavioral Therapy (iCBT) in reducing symptoms of prolonged grief disorder in adults who have lost a loved one. Participants will be randomly assigned to either the iCBT group, an active control group, or a waitlist control group. The study aims to assess the short and long-term effects of iCBT on symptoms of prolonged grief, posttraumatic stress, and depression, while also exploring the mechanisms that contribute to its effectiveness. Follow-up assessments will be conducted at 6 and 12 months post-treatment to gauge the lasting impact of the intervention.
Who should consider this trial
Good fit: Ideal candidates are adults residing in Sweden who have experienced the death of a loved one at least six months prior and are suffering from prolonged grief disorder.
Not a fit: Patients with ongoing severe psychiatric issues or those requiring more urgent care may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly alleviate prolonged grief symptoms and improve mental health outcomes for affected individuals.
How similar studies have performed: Previous studies have indicated that Cognitive Behavioral Therapy can be effective for prolonged grief, but this trial aims to expand on that with a larger sample size and comprehensive follow-up assessments.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Currently residing in Sweden * Lost a relative or close friend to any cause of death at least six months ago * Suffers from prolonged grief disorder Exclusion Criteria: * Ongoing severe psychiatric problems that may prevent treatment implementation or require more urgent care (e.g., participants with untreated psychotic disorder, untreated bipolar disorder, ongoing substance abuse, elevated suicide risk) * Change in dosage of any medication for mental health issues (e.g., antidepressant medication) in the past four weeks or in the next two months
Where this trial is running
Uppsala and 1 other locations
- Region Uppsala, KBT via nätet, Nära vård digitalt — Uppsala, Sweden (Recruiting)
- Uppsala university, Dep of Womens and Childrens Health — Uppsala, Sweden (Recruiting)
Study contacts
- Study coordinator: Josefin Sveen, Professor
- Email: josefin.sveen@uu.se
- Phone: +46 738 66 70 87
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.