Home-based cardiovascular health screening for people turning 50, 55, 60, 65, 70 or 75 in Uppsala

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

U-SCREEN is a pragmatic randomized trial in Region Uppsala that assigns residents aged 50, 55, 60, 65, 70 or 75 to either a home-based, multimodal screening package or to usual care. The screening arm includes a home blood pressure monitor, a dried blood spot kit for ApoB, HbA1c and creatinine, and a digital questionnaire to assess risk. Primary goals are to see if this approach identifies more actionable risk factors, influences preventive treatment, and impacts cardiovascular events, healthcare use, costs, and patient-reported outcomes. The study uses register-based follow-up with a 1:1 randomization and targets up to 10,000 participants recruited between 2024 and 2027. It is led by Johan Sundström with Region Uppsala Public Health and Care and Uppsala University Hospital involved in the conduct.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Resident in Region Uppsala, Sweden
* Turning 50, 55, 60, 65, 70 or 75 years during recruitment period
* Able to provide informed consent

Exclusion Criteria:

* Inability to provide informed consent
* Protected identity

Where it's running

• Uppsala University Hospital
  Uppsala, Sweden Recruiting

Study contacts

• Principal investigator: Johan Sundström, MD, PhD — Uppsala University
• Study coordinator: Johan Sundström, MD, PhD
• Email: johan.sundstrom@uu.se
• Phone: +46 70 422 52 20

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.