Evaluating night splinting after needle fasciotomy for Dupuytren's contracture

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of night splinting following percutaneous needle fasciotomy (PNF) in patients with Dupuytren's contracture. Patients will be randomized into two groups: one receiving standard physical therapy and night splinting, and the other receiving physical therapy without splinting. The primary goal is to determine if night splinting reduces the recurrence rate of Dupuytren's contracture after PNF. This approach aims to provide insights into optimizing post-treatment care for this condition.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18 years of age and older,
* Palpable Dupuytren strand with passive extension deficit according to stadium 1 and 2 of the classification of Tubiana in one or two fingers excluding the thumb, defined as at least 30 degrees in the MCP joint and/or at least 20 degrees in the PIP joint and a maximum of 75 degrees in the MCP or PIP joint

Exclusion Criteria:

* Multiple, invasive or wide strands in the palm,
* Skin irritation,
* Strand localization in the digit only,
* Digital nerve injury,
* Any former treatment for Dupuytren's contracture in the same digit,
* Thumb contracture,
* Stadium 3 and 4 according to the classification of Tubiana

Where it's running

• Falu Lasarett
  Falun, Dalarna County, Sweden Recruiting
• Akademiska Sjukhuset
  Uppsala, Uppsala County, Sweden Recruiting
• Universitetssjukhuset Örebro
  Örebro, Örebro County, Sweden Recruiting

Study contacts

• Principal investigator: Stephan Wilbrand, MD, PhD — Uppsala University
• Study coordinator: Daniel Muder, MD
• Email: daniel.muder@surgsci.uu.se
• Phone: 0046-23-490000

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Treatment options for Dupuytren's contracture

  This study is testing whether adding a corticosteroid injection to a needle treatment helps people with Dupuytren's contracture move their fingers better.

  Recruiting Phase 4 Regionshospitalet Silkeborg · Silkeborg · NCT05440240

• Evaluating post-surgery radiation treatment for Dupuytren's disease

  This study is testing whether adding radiation treatment after surgery for Dupuytren's disease can help improve hand function and reduce symptoms for patients.

  Recruiting University of Minnesota · Minneapolis, Minnesota · NCT04122313

• CNT201 collagenase injection for Dupuytren’s: safety and signals of efficacy in adults

  A randomized, placebo-controlled study will test CNT201 injections to see if they are safe and help improve finger contractures in adults with Dupuytren’s disease.

  Recruiting Phase 1/2 Connext · Kippa-Ring, Queensland · NCT07640425

• Evaluating a new ultrasound-guided technique for Dupuytren's contracture

  This study is testing a new ultrasound-guided procedure to see if it can safely improve hand function for people with Dupuytren's contracture while causing fewer problems than traditional surgery.

  Recruiting Mansoura University Hospital · Al Mansurah, Dakahlia Governorate · NCT06788847

• Using radiation therapy to prevent Dupuytren's contracture recurrence after treatment

  This study is testing if targeted radiation therapy can help prevent Dupuytren's contracture from coming back after treatment in people aged 45 and older.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06330545

• Treatment for early Dupuytren's disease using vitamin E cream

  This study is testing if using vitamin E cream can help people with early Dupuytren's disease stop their fingers from getting worse.

  Recruiting Phase 2 Universitaire Ziekenhuizen KU Leuven · Leuven, Vlaams-Brabant · NCT06321991

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.