Clinical trial Recruiting at 1 site Interventional Ages 60 to 80

Direct lateral vs posterolateral approach for cemented total hip replacement

Official title: Randomized Study of Surgical Approach of THA. CT/RSA, Radiography, HHS and Muscle Strength.

Run by Uppsala University · NCT07851597 · Data updated 2026-11-12

This study tests whether the surgical approach affects muscle healing and early recovery after cemented total hip replacement in people with hip OA.

Quick facts

Study typeInterventional
Ages60 Years to 80 Years
SexAll
Enrollment40 (estimated)
SponsorUppsala University
Academic / other
Locations1 site (Gävle)
StatusRecruiting
StartedMarch 1, 2021
Main results expectedDecember 2028
Study endsDecember 2028
Registry record updatedOctober 1, 2026
Trial IDNCT07851597 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with hip osteoarthritis planned for cemented primary total hip arthroplasty, eligible for randomization to either direct lateral or posterolateral approach.

Probably not a fit

Patients who have contraindications to either surgical approach or who do not experience differences in muscle healing may not see a benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this prospective, randomized trial, 40 patients with hip osteoarthritis undergoing cemented primary total hip arthroplasty are assigned to either a direct lateral or a posterolateral surgical approach. The study uses CT-based micromotion analysis to assess whether muscle reattachment to bone remains stable over post-operative time, along with radiographic imaging and clinical assessments to track pain, strength, limp, and functional scores. Outcomes include correlations between muscle healing and functional recovery after surgery. Patients are followed with imaging, clinical scoring, and questionnaires to capture mobility and pain changes. The trial compares two common approaches to see which yields better muscle stability and recovery after THA.

Why it matters

Potential benefit: If successful, the results could guide surgeons to choose an approach that promotes better muscle healing and faster functional recovery after hip replacement.

How similar studies have gone: Previous work using radiographic and functional assessments in THA has shown approach-related differences in soft-tissue outcomes, but this trial adds CT-based micromotion analysis to directly assess muscle stability.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* hip osteoarthritis as indication for THA surgery
* use of cemented prosthetic Components

Exclusion Criteria:

* symptomatic osteoarthritis on the contralateral hip
* neuromuscular disorder
* dementia
* BMI\>40
* previous surgery on any hip

Where it's running

  • Gävle hospital orthopaedic clinic
    Gävle, Sweden
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.