Direct lateral vs posterolateral approach for cemented total hip replacement
Official title: Randomized Study of Surgical Approach of THA. CT/RSA, Radiography, HHS and Muscle Strength.
Run by Uppsala University · NCT07851597 · Data updated 2026-11-12
This study tests whether the surgical approach affects muscle healing and early recovery after cemented total hip replacement in people with hip OA.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 60 Years to 80 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Uppsala University Academic / other |
| Locations | 1 site (Gävle) |
| Status | Recruiting |
| Started | March 1, 2021 |
| Main results expected | December 2028 |
| Study ends | December 2028 |
| Registry record updated | October 1, 2026 |
| Trial ID | NCT07851597 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with hip osteoarthritis planned for cemented primary total hip arthroplasty, eligible for randomization to either direct lateral or posterolateral approach.
✕Probably not a fit
Patients who have contraindications to either surgical approach or who do not experience differences in muscle healing may not see a benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In this prospective, randomized trial, 40 patients with hip osteoarthritis undergoing cemented primary total hip arthroplasty are assigned to either a direct lateral or a posterolateral surgical approach. The study uses CT-based micromotion analysis to assess whether muscle reattachment to bone remains stable over post-operative time, along with radiographic imaging and clinical assessments to track pain, strength, limp, and functional scores. Outcomes include correlations between muscle healing and functional recovery after surgery. Patients are followed with imaging, clinical scoring, and questionnaires to capture mobility and pain changes. The trial compares two common approaches to see which yields better muscle stability and recovery after THA.
Why it matters
Potential benefit: If successful, the results could guide surgeons to choose an approach that promotes better muscle healing and faster functional recovery after hip replacement.
How similar studies have gone: Previous work using radiographic and functional assessments in THA has shown approach-related differences in soft-tissue outcomes, but this trial adds CT-based micromotion analysis to directly assess muscle stability.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * hip osteoarthritis as indication for THA surgery * use of cemented prosthetic Components Exclusion Criteria: * symptomatic osteoarthritis on the contralateral hip * neuromuscular disorder * dementia * BMI\>40 * previous surgery on any hip
Where it's running
-
Gävle hospital orthopaedic clinic
Gävle, Sweden Recruiting
Study contacts
- Study coordinator: Dimitrios Sotiriou, Medical doctor
- Email: dimitrios.sotiriou@regiongavleborg.se
- Phone: +46762810301
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.