Translating and validating a questionnaire for opioid misuse in Swedish pain patients
Translation and Validation of the COMM and ASI-SR - Instruments for Assessing Substance Use Disorder Development in a Swedish Population of Patients With Long-term Pain Treated With Opioids
This study is testing a new Swedish questionnaire to see if it can help identify opioid misuse among pain patients who are using opioids for treatment.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 400 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Uppsala University Academic / other |
| Locations | 1 site (Uppsala, Uppland) |
| Trial ID | NCT06084520 on ClinicalTrials.gov |
What this trial studies
This observational study aims to translate the Current Opinion Misuse Measure (COMM) into Swedish and validate it using the Addiction Severity Index-Self Report (ASI-SR) among pain patients treated with opioids. The study will assess the reliability and validity of the COMM instrument in detecting substance use disorders in this population. Additionally, it will investigate the prevalence of alcohol and illicit substance use among patients receiving long-term opioid treatment compared to those who are not. Blood samples will also be collected for future neurobiological analysis related to pain treatment.
Who should consider this trial
Good fit: Ideal candidates include Swedish-speaking adults aged 18-75 with long-term, non-cancer-related pain who have been on opioid treatment for at least one month.
Not a fit: Patients with serious cognitive disorders or ongoing diseases that prevent them from completing the study may not benefit from this research.
Why it matters
Potential benefit: If successful, this study could provide a validated tool for early detection of substance use disorders in Swedish patients undergoing opioid treatment.
How similar studies have performed: While the approach of translating and validating assessment tools is common, this specific study addresses a novel gap in the Swedish population regarding opioid misuse assessment.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Intervention group: * Patients with long-term, non-cancer-related pain (\>3 months) at least 3 days a week * opioid treatment for at least 1 month during last 6 months * age 18-75 years * fluent in spoken and written Swedish. Control group: * Patients with long-term, non-cancer-related pain (\>3 months) at least 3 days a week * no opioid treatment at inclusion and during last 3 months * age 18-75 years * fluent in spoken and written Swedish Exclusion Criteria: * ongoing diseases or conditions that prevents the patient from completing to the study according to the doctor's assessment * serious cognitive disorder that makes answering the questions impossible. - - ongoing or treated cancer in the last 10 years * Insufficient knowledge of Swedish
Where this trial is running
Uppsala, Uppland
- Multidisciplinary Pain Center — Uppsala, Uppland, Sweden (Recruiting)
Study contacts
- Principal investigator: Rolf Karlsten, PhD — Uppsala University
- Study coordinator: Lenka Katila, MD
- Email: lenka.katila@uu.se
- Phone: +46186113739
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.