Translating and validating a questionnaire for opioid misuse in Swedish pain patients
Official title: Translation and Validation of the COMM and ASI-SR - Instruments for Assessing Substance Use Disorder Development in a Swedish Population of Patients With Long-term Pain Treated With Opioids
Run by Uppsala University · NCT06084520 · Data updated 2026-11-12
This study is testing a new Swedish questionnaire to see if it can help identify opioid misuse among pain patients who are using opioids for treatment.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 400 (estimated) |
| Sponsor | Uppsala University Academic / other |
| Locations | 1 site (Uppsala, Uppland) |
| Status | Recruiting |
| Started | December 1, 2023 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2026 |
| Registry record updated | May 10, 2024 |
| Trial ID | NCT06084520 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include Swedish-speaking adults aged 18-75 with long-term, non-cancer-related pain who have been on opioid treatment for at least one month.
✕Probably not a fit
Patients with serious cognitive disorders or ongoing diseases that prevent them from completing the study may not benefit from this research.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to translate the Current Opinion Misuse Measure (COMM) into Swedish and validate it using the Addiction Severity Index-Self Report (ASI-SR) among pain patients treated with opioids. The study will assess the reliability and validity of the COMM instrument in detecting substance use disorders in this population. Additionally, it will investigate the prevalence of alcohol and illicit substance use among patients receiving long-term opioid treatment compared to those who are not. Blood samples will also be collected for future neurobiological analysis related to pain treatment.
Why it matters
Potential benefit: If successful, this study could provide a validated tool for early detection of substance use disorders in Swedish patients undergoing opioid treatment.
How similar studies have gone: While the approach of translating and validating assessment tools is common, this specific study addresses a novel gap in the Swedish population regarding opioid misuse assessment.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Intervention group: * Patients with long-term, non-cancer-related pain (\>3 months) at least 3 days a week * opioid treatment for at least 1 month during last 6 months * age 18-75 years * fluent in spoken and written Swedish. Control group: * Patients with long-term, non-cancer-related pain (\>3 months) at least 3 days a week * no opioid treatment at inclusion and during last 3 months * age 18-75 years * fluent in spoken and written Swedish Exclusion Criteria: * ongoing diseases or conditions that prevents the patient from completing to the study according to the doctor's assessment * serious cognitive disorder that makes answering the questions impossible. - - ongoing or treated cancer in the last 10 years * Insufficient knowledge of Swedish
Where it's running
-
Multidisciplinary Pain Center
Uppsala, Uppland, Sweden Recruiting
Study contacts
- Principal investigator: Rolf Karlsten, PhD — Uppsala University
- Study coordinator: Lenka Katila, MD
- Email: lenka.katila@uu.se
- Phone: +46186113739
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.