Sponsor or institution
Clinical trials and research at IRCCS Policlinico S. Donato
As of November 12, 2026, Find a Trial lists 35 clinical trials run by IRCCS Policlinico S. Donato that are recruiting, in Italy. By phase: Phase 4 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 35Clinical trials
- 1Country
Newest trials
All recruiting trials (35)
-
Claudin-2 Immunostaining to Detect Active or Inactive Inflammation in IBD Biopsies
This study tests whether staining for Claudin-2 in intestinal biopsy samples can help identify active vs. inactive inflammation in people with ulcerative colitis or Crohn's disease.
-
Using 4D Flow MRI to characterize left ventricular failure
This project will test whether automated 4D Flow MRI analysis can measure left ventricular dysfunction in adults with severe aortic stenosis who are scheduled for TAVR.
-
Measuring aortic wall strength and thickness in ascending aortic aneurysms
This project tests whether measuring the strength and thickness of removed ascending aortic tissue can help predict rupture risk for patients having surgery for aortic root or ascending aortic aneurysms.
-
Finding signs of Alzheimer's in people with subjective memory complaints
The study will test whether inexpensive, easy-to-get measures—like blood markers, EEG and automated speech analysis—can help identify early Alzheimer's in people who notice memory or thinking changes but have normal standard tests.
-
Risk factors and health impact in people with genetic thoracic aortic disease
See how lifestyle, stress, reproductive history, and other health issues relate to risk and quality of life in people with genetic thoracic aortic aneurysms.
-
AI and 3D ultrasound mapping of mitral valve prolapse shape and function.
This project tests an automated AI system that uses intraoperative 3D transesophageal ultrasound to map mitral valve anatomy and create patient-specific biomechanical models for adults having surgery for degenerative mitral valve prolapse.
-
International multicenter use of the Navitor/Navitor Vision transcatheter aortic valve
This project will test how the Navitor/Navitor Vision transcatheter aortic valve performs in people with symptomatic severe native aortic stenosis treated at experienced centers across Europe and the UK.
-
Intensive GDMT optimization for women after heart failure hospitalization
This study tests whether rapidly increasing and closely monitoring heart failure meds in women after hospitalization can reduce death or readmission within a year.
-
Fibroblast study of COL5A mutations and aortic aneurysms
Researchers will test skin-derived fibroblasts from adults with COL5A mutations to see if cellular differences help explain why some people develop aortic aneurysms while others don’t.
-
Prontosan Wound Gel X in heart surgery shows whether it lowers surgical site infections
This study tests if applying Prontosan Wound Gel X during elective heart surgery can lower superficial surgical site infections in adults.
-
Cardiovascular risk in people with Crohn's disease and ulcerative colitis
This study tests whether people with inflammatory bowel disease have different heart-attack or stroke risk over two years compared with matched controls.
-
ARTEMIS: JenaValve Trilogy data collection for severe aortic regurgitation
This project will try the JenaValve Trilogy transcatheter heart valve in adults with severe native aortic regurgitation who are high or prohibitive risk for open-heart surgery.
-
Observing exercise and heart function in patients with Anderson-Fabry Disease
This study looks at how exercise affects heart function in people with Anderson-Fabry Disease to better understand their health and quality of life.
-
Comparing heart valve prostheses for treating aortic stenosis
This study is testing how well different types of heart valve replacements work for people with severe aortic stenosis, especially those with smaller heart openings.
-
Evaluating new methods for predicting cardiovascular disease risk in Italy
This study is testing whether using genetic and imaging information can help people in Italy understand their risk of heart disease better and improve their health through tailored advice and treatment.
-
Monitoring system to predict kidney injury after heart surgery
This study is testing a new monitoring system to see if it can help predict and prevent kidney injury in adults and infants undergoing heart surgery.
-
Assessing cardiovascular and brain interactions in healthy adults
This study tests how the heart and brain work together in healthy adults to see if there’s a link between physical and mental health.
-
Creating a network of biobanks for rare diseases in Italy
This study is trying to set up a network of biobanks in Italy to collect samples from patients with rare cardiovascular and neurological diseases to improve research and treatment options.
-
Improving diagnosis of anomalous coronary arteries
This study is testing a new online tool that uses advanced technology to help doctors better diagnose and understand the risks for patients with unusual heart artery conditions.
-
Identifying genetic markers for Brugada Syndrome diagnosis
This study is testing if new genetic tools can help doctors better diagnose Brugada Syndrome and create more personalized treatment plans for patients.
-
Measuring how the brain, autonomic system, and blood vessels interact
This project tests new mathematical and monitoring methods to measure how brain activity, autonomic function, and blood flow interact in adults scheduled for major heart surgery, with the goal of linking these patterns to depression and cardiac outcomes.
-
Improving pain control after abdominal aortic aneurysm surgery
This study tests which pain relief method works better for adults after surgery for abdominal aortic aneurysms: an epidural or a series of injections in the abdominal muscles.
-
Examining the TMEM230 gene's role in atherosclerosis
This study is trying to see how the TMEM230 gene affects atherosclerosis in patients by looking at tissue and blood samples to better understand the condition.
-
Assessing white matter changes in mild cognitive impairment and Alzheimer's disease
This study is testing how changes in brain white matter can help us understand and diagnose mild cognitive impairment and Alzheimer's disease better.
-
Examining microRNAs in patients with Critical Limb Ischemia
This study is trying to see if certain tiny molecules in muscle tissue can help us understand critical limb ischemia better by comparing patients with this condition to those who have a different blood vessel issue.
-
Identifying RNA biomarkers in patients with acute coronary syndrome
This study is trying to find specific RNA markers in the blood of people with acute coronary syndrome to see if they can predict heart problems after treatment.
-
Predicting brain complications after heart surgery
This study is testing two ways to measure how well the brain controls blood flow during heart surgery to see if it can help predict the risk of complications like strokes afterward.
-
Evaluating treatments for severe aortic valve stenosis in elderly patients in Italy
This study is trying to see which treatments work best for elderly patients with severe aortic valve stenosis who need valve replacement, to improve their quality of life.
-
Evaluating aortic stiffness in patients with genetic aortopathies
This study is testing how stiff the arteries are in people with aortic aneurysms caused by genetic conditions to see if it helps understand their risk better.
-
Psychological support for adults with Marfan syndrome
This study looks at why adults with Marfan syndrome seek psychological support and how their condition affects their mental health and coping skills.
-
Evaluating cardiovascular and cerebrovascular control in healthy individuals
This study tests how well the heart and brain work together in healthy people by looking at their responses to changes in position.
-
Assessing facial features in Marfan syndrome
This study is trying to identify and track the facial features of people with Marfan syndrome to help with earlier diagnosis and understanding of the condition.
-
Understanding Anomalous Aortic Origin of Coronary Artery
This study looks at patients with Anomalous Aortic Origin of Coronary Artery to see what factors might lead to heart problems and to track any rare issues over time after treatment.
-
Evaluating Clopidogrel Resistance in Patients Undergoing Carotid Stenting
This study is testing whether switching to a different medication called Ticagrelor can help patients who don't respond well to Clopidogrel during carotid stenting procedures.
-
Investigating RNA profiles in heart failure and aortic stenosis
This study is trying to see how certain RNA molecules in the blood and heart tissue of people with heart failure and aortic stenosis might help us understand their heart problems better and identify new ways to diagnose them.
Quick answers
How many clinical trials run by IRCCS Policlinico S. Donato are recruiting right now?
35, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in Italy. Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.