Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Assessing cardiovascular and brain interactions in healthy adults

Official title: Dynamic Cardio-, Cerebro-vascular and Cortical Interaction in Healthy Adult Subjects

Run by IRCCS Policlinico S. Donato · NCT06785181 · Data updated 2026-11-12

This study tests how the heart and brain work together in healthy adults to see if there’s a link between physical and mental health.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment50 (estimated)
SponsorIRCCS Policlinico S. Donato
Academic / other
Locations1 site (San Donato Milanese, Milano)
StatusRecruiting
StartedOctober 3, 2024
Main results expectedOctober 3, 2027
Study endsOctober 3, 2027
Registry record updatedJuly 6, 2026
Trial IDNCT06785181 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are healthy adults over the age of 18 who can provide informed consent.

Probably not a fit

Patients with definite diseases of the autonomic nervous system or cardiovascular system, central nervous system disorders, or those on certain medications may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the autonomic function, cerebral autoregulation, and cortical activity in healthy adult subjects. It will analyze various physiological parameters, including cardiac and cerebrovascular variability, during both resting and active standing conditions. Additionally, psychometric tests will be conducted to assess any depressive symptoms among participants. The goal is to understand how these physiological functions correlate with psychological dimensions.

Why it matters

Potential benefit: If successful, this study could enhance our understanding of cardiovascular and brain interactions, potentially leading to better management of cardiac diseases.

How similar studies have gone: While this study explores a novel approach, similar studies assessing cardiovascular and brain interactions have shown promising results.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* age older than 18 years
* spontaneous sinus rhythm
* signed informed consent

Exclusion Criteria:

* Definite diseases of the Autonomic Nervous System (SNA) or the cardiovascular system
* Central nervous system disorders
* subjects under drug therapy that may affect the cardiovascular system
* pregnancy
* previous diagnosis of depression

Where it's running

  • IRCCS Policlinico San Donato
    San Donato Milanese, Milano, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.