Assessing cardiovascular and brain interactions in healthy adults
Dynamic Cardio-, Cerebro-vascular and Cortical Interaction in Healthy Adult Subjects
This study tests how the heart and brain work together in healthy adults to see if there’s a link between physical and mental health.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | IRCCS Policlinico S. Donato Academic / other |
| Locations | 1 site (San Donato Milanese, Milano) |
| Trial ID | NCT06785181 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the autonomic function, cerebral autoregulation, and cortical activity in healthy adult subjects. It will analyze various physiological parameters, including cardiac and cerebrovascular variability, during both resting and active standing conditions. Additionally, psychometric tests will be conducted to assess any depressive symptoms among participants. The goal is to understand how these physiological functions correlate with psychological dimensions.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy adults over the age of 18 who can provide informed consent.
Not a fit: Patients with definite diseases of the autonomic nervous system or cardiovascular system, central nervous system disorders, or those on certain medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of cardiovascular and brain interactions, potentially leading to better management of cardiac diseases.
How similar studies have performed: While this study explores a novel approach, similar studies assessing cardiovascular and brain interactions have shown promising results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * age older than 18 years * spontaneous sinus rhythm * signed informed consent Exclusion Criteria: * Definite diseases of the Autonomic Nervous System (SNA) or the cardiovascular system * Central nervous system disorders * subjects under drug therapy that may affect the cardiovascular system * pregnancy * previous diagnosis of depression
Where this trial is running
San Donato Milanese, Milano
- IRCCS Policlinico San Donato — San Donato Milanese, Milano, Italy (Recruiting)
Study contacts
- Study coordinator: Vlasta Bari, PhD
- Email: vlasta.bari@grupposandonato.it
- Phone: +390252774381
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.