Assessing cardiovascular and brain interactions in healthy adults
Official title: Dynamic Cardio-, Cerebro-vascular and Cortical Interaction in Healthy Adult Subjects
Run by IRCCS Policlinico S. Donato · NCT06785181 · Data updated 2026-11-12
This study tests how the heart and brain work together in healthy adults to see if there’s a link between physical and mental health.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | IRCCS Policlinico S. Donato Academic / other |
| Locations | 1 site (San Donato Milanese, Milano) |
| Status | Recruiting |
| Started | October 3, 2024 |
| Main results expected | October 3, 2027 |
| Study ends | October 3, 2027 |
| Registry record updated | July 6, 2026 |
| Trial ID | NCT06785181 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are healthy adults over the age of 18 who can provide informed consent.
✕Probably not a fit
Patients with definite diseases of the autonomic nervous system or cardiovascular system, central nervous system disorders, or those on certain medications may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the autonomic function, cerebral autoregulation, and cortical activity in healthy adult subjects. It will analyze various physiological parameters, including cardiac and cerebrovascular variability, during both resting and active standing conditions. Additionally, psychometric tests will be conducted to assess any depressive symptoms among participants. The goal is to understand how these physiological functions correlate with psychological dimensions.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of cardiovascular and brain interactions, potentially leading to better management of cardiac diseases.
How similar studies have gone: While this study explores a novel approach, similar studies assessing cardiovascular and brain interactions have shown promising results.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * age older than 18 years * spontaneous sinus rhythm * signed informed consent Exclusion Criteria: * Definite diseases of the Autonomic Nervous System (SNA) or the cardiovascular system * Central nervous system disorders * subjects under drug therapy that may affect the cardiovascular system * pregnancy * previous diagnosis of depression
Where it's running
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IRCCS Policlinico San Donato
San Donato Milanese, Milano, Italy Recruiting
Study contacts
- Study coordinator: Vlasta Bari, PhD
- Email: vlasta.bari@grupposandonato.it
- Phone: +390252774381
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.